In an unblinded randomized controlled trial involving 106 patients with malignant pleural effusion, Davies and colleagues sought to determine whether indwelling pleural catheters were superior to chest tube and talc slurry pleurodesis in relieving dyspnea. Patients measured their dyspnea daily using a 100-mm visual analog scale with 0 mm representing none and 100 representing maximum dyspnea.
Dr Brunkhorst and coauthors for the German Study Group Competence Network Sepsis report on the effect of empirical treatment with moxifloxacin and meropenem vs meropenem on sepsis-related organ dysfunction in patients with severe sepsis.
Smith-Bindman and colleagues conducted a population-based study of diagnostic imaging among integrated health care systems between 1996 and 2010. They investigated rates of the use of advanced diagnostic imaging and cumulative annual radiation exposure.
Jagsi and coauthors analyze 800 responses to a survey of 1729 physician researchers to determine salary differences by gender and other characteristics.
Bach and coauthors conducted a systematic review of the evidence regarding the benefits and harms of lung cancer screening using low-dose computed tomography. They examined lung cancer mortality and all-cause mortality in 8 randomized controlled trials and 13 cohort studies identified from 591 citations.