Acute respiratory distress syndrome was defined in 1994, despite issues regarding the reliability and validity of the definition. Using a consensus process involving a panel of experts, Ranieri and colleagues developed the Berlin Definition that focused on feasibility, reliability, validity, and objective evaluation of its performance.
To determine whether adding lipid markers to the panel of current cardiovascular disease (CVD) risk markers would enhance CVD risk assessment, the Emerging Risk Factors Collaboration reviewed available records from 165544 participants in 37 prospective cohort trials, in which 15126 had incident fatal or nonfatal CVD outcomes.
Among a population-based cohort of 1816824 adults in Alberta, Canada, Hemmelgarn and coauthors evaluate the extent to which age is associated with the likelihood of treatment of kidney failure.
King and coauthors conducted a prospective cohort study of adults who underwent bariatric surgery at 10 US hospitals to assess the prevalence of alcohol use disorders before and after surgery.
O'Grady and colleagues discuss ventilator-associated pneumonia (VAP), one of the most common infections in patients requiring endotracheal tubes with
mechanical ventilation; the current recommendations for interventions designed to reduce rates of VAP; and what is known about whether these interventions
improve patient outcomes.
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