December 12, 2012, Vol 308, No. 22, Pages 2307-2418

Preliminary Communication

ONLINE FIRST

Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction: The TIME Randomized Trial

Jay H. Traverse, MD; Timothy D. Henry, MD; Carl J. Pepine, MD; et al.

Abstract Full Text

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JAMA. 2012;308(22):2380-2389. doi:10.1001/jama.2012.28726

Traverse and coauthors for the Cardiovascular Cell Therapy Research Network report on the effect on left ventricular function of the use and timing of bone marrow mononuclear cell delivery after acute myocardial infarction. In an accompanying Editorial, Marbán and Malliaras discuss the mixed results for bone marrow–derived cell therapy for ischemic heart disease.

Editorial
Mixed Results for Bone Marrow–Derived Cell Therapy for Ischemic Heart Disease
Eduardo Marbán, MD, PhD; Konstantinos Malliaras, MD

ONLINE FIRST

Comparison of Allogeneic vs Autologous Bone Marrow–Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy: The POSEIDON Randomized Trial

Joshua M. Hare, MD; Joel E. Fishman, MD, PhD; Gary Gerstenblith, MD; et al.

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JAMA. 2012;308(22):2369-2379. doi:10.1001/jama.2012.25321

To test whether allogeneic mesenchymal stem cells (MSCs) are as safe and effective as autologous MSCs, Hare and coauthors injected 30 patients who had left ventricular dysfunction due to ischemic cardiomyopathy with stem cells by transendocardial stem cell injection. See the related Editorial by Marbán and Malliaras.

Editorial
Mixed Results for Bone Marrow–Derived Cell Therapy for Ischemic Heart Disease
Eduardo Marbán, MD, PhD; Konstantinos Malliaras, MD

Effect of Acetazolamide and AutoCPAP Therapy on Breathing Disturbances Among Patients With Obstructive Sleep Apnea Syndrome Who Travel to Altitude: A Randomized Controlled Trial

Tsogyal D. Latshang, MD; Yvonne Nussbaumer-Ochsner, MD; Rahel M. Henn, BMS; et al.

Abstract Full Text

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JAMA. 2012;308(22):2390-2398. doi:10.1001/jama.2012.94847

Latshang and coauthors evaluated whether acetazolamide combined with autoadjusted continuous positive airway pressure (autoCPAP) provides better oxygenation and control of sleep-related breathing disturbances than autoCPAP alone in 51 patients with obstructive sleep apnea syndrome spending a few days at moderate altitude.

Research Letter

Pancreas Organ Weight in Individuals With Disease-Associated Autoantibodies at Risk for Type 1 Diabetes

Martha Campbell-Thompson, DVM, PhD; Clive Wasserfall, MS; Emily L. Montgomery, BS; et al.

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JAMA. 2012;308(22):2337-2339. doi:10.1001/jama.2012.15008

This Week in JAMA

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JAMA. 2012;308(22):2307. doi:10.1001/jama.2012.3378

Audio Editors' Summary: JAMA: 2012-12-11, Vol. 308, No. 22, Editor's Audio Summary

Viewpoint

ONLINE FIRST

Biomedical Research in an Age of Austerity

Hamilton Moses III, MD; E. Ray Dorsey, MD, MBA

Abstract Full Text

JAMA. 2012;308(22):2341-2342. doi:10.1001/jama.2012.14846

ONLINE FIRST

Facing the NIH Funding Crisis: How Professional Societies Can Help

Robert Hromas, MD; Janis L. Abkowitz, MD; Armand Keating, MD

Abstract Full Text

JAMA. 2012;308(22):2343-2344. doi:10.1001/jama.2012.45067

Lixivaptan for Hyponatremia—The Numbers Game

Ryan T. Borne, MD; Mori J. Krantz, MD

Abstract Full Text

JAMA. 2012;308(22):2345-2346. doi:10.1001/jama.2012.54515

A Piece of My Mind

Enough, Already

Michael D. Stillman, MD

Abstract Full Text

JAMA. 2012;308(22):2347-2348. doi:10.1001/jama.2012.14475

Original Contribution

ONLINE FIRST

Age and Association of Kidney Measures With Mortality and End-stage Renal Disease

Stein I. Hallan, MD, PhD; Kunihiro Matsushita, MD, PhD; Yingying Sang, MS; et al.

Abstract Full Text

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JAMA. 2012;308(22):2349-2360. doi:10.1001/jama.2012.16817

Hallan and coauthors conducted an individual-level meta-analysis of 2 051 244 participants from 46 worldwide cohorts to evaluate effect modification by age of the association of eGFR and albuminuria with clinical risk of all-cause mortality and end-stage renal disease. In an editorial, de Boer discusses chronic kidney disease in older adults.

Editorial
Chronic Kidney Disease—A Challenge for All Ages
Ian H. de Boer, MD, MS

Prevalence of Nonrefractive Visual Impairment in US Adults and Associated Risk Factors, 1999-2002 and 2005-2008

Fang Ko, MD; Susan Vitale, PhD, MHS; Chiu-Fang Chou, DrPH; et al.

Abstract Full Text

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JAMA. 2012;308(22):2361-2368. doi:10.1001/jama.2012.85685

Friedman and coauthors estimate prevalence of nonrefractive visual impairment and describe its relationship with diabetes and other risk factors in 10 480 participants aged 20 years or older from NHANES 1999-2002 and 2005-2008. In an accompanying Editorial, Musch and Gardner discuss diabetes and nonrefractive visual impairment.

Audio Author Interview: Prevalence of Nonrefractive Visual Impairment in US Adults and Associated Risk Factors, 1999-2002 and 2005-2008

Editorial
Diabetes and Nonrefractive Visual Impairment: The Young Have It
David C. Musch, PhD, MPH; Thomas W. Gardner, MD, MS

Editorial

ONLINE FIRST

Chronic Kidney Disease—A Challenge for All Ages

Ian H. de Boer, MD, MS

Abstract Full Text

JAMA. 2012;308(22):2401-2402. doi:10.1001/jama.2012.30761

Diabetes and Nonrefractive Visual Impairment: The Young Have It

David C. Musch, PhD, MPH; Thomas W. Gardner, MD, MS

Abstract Full Text

JAMA. 2012;308(22):2403-2404. doi:10.1001/jama.2012.114286

ONLINE FIRST

Mixed Results for Bone Marrow–Derived Cell Therapy for Ischemic Heart Disease

Eduardo Marbán, MD, PhD; Konstantinos Malliaras, MD

Abstract Full Text

JAMA. 2012;308(22):2405-2406. doi:10.1001/jama.2012.64751

JAMA Clinical Challenge

Clinician's Corner

Antibiotic-Refractory Sinusitis

Javier Munoz, MD; Philip Kuriakose, MD

Abstract Full Text

JAMA. 2012;308(22):2399-2400. doi:10.1001/jama.2012.91077

Medical News & Perspectives

Studies Continue to Show No Benefit From Annual Physicals in Healthy Adults

Mike Mitka, MSJ

Abstract Full Text

JAMA. 2012;308(22):2321-2322. doi:10.1001/jama.2012.36756

1000 Genomes Project Finds Substantial Genetic Variation Among Populations

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2012;308(22):2322-2325. doi:10.1001/jama.2012.88674

Injections May Take the Bite Out of Malaria Studies

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2012;308(22):2325. doi:10.1001/jama.2012.105690

News From the Centers for Disease Control and Prevention

Multistate Outbreak of Fungal Infection Associated with Injection of Methylprednisolone Acetate Solution from a Single Compounding Pharmacy—United States, 2012

Abstract Full Text

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JAMA. 2012;308(22):2328-2331. doi:10.1001/jama.2012.64944

Influenza A (H3N2) Variant Virus-Related Hospitalizations—Ohio, 2012

Abstract Full Text

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JAMA. 2012;308(22):2331-2333. doi:10.1001/jama.2012.14341

Capitol Health Call

Sports-Related Concussions

Mike Mitka, MSJ

Abstract Full Text

JAMA. 2012;308(22):2327-2327. doi:10.1001/jama.2012.97077

Lab Reports

Lupus Antibodies Fight Cancer

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2012;308(22):2326. doi:10.1001/jama.2012.111747

Eradicating C difficile

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2012;308(22):2326. doi:10.1001/jama.2012.111751

Help for Ex-Smokers?

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2012;308(22):2326. doi:10.1001/jama.2012.111754

Anesthesia and Sleep Circuits

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2012;308(22):2326. doi:10.1001/jama.2012.77558

Physician Self-Referrals

Mike Mitka, MSJ

Abstract Full Text

JAMA. 2012;308(22):2327. doi:10.1001/jama.2012.111282

Physicians in Congress

Mike Mitka, MSJ

Abstract Full Text

JAMA. 2012;308(22):2327. doi:10.1001/jama.2012.111327

Improving Military Review

Mike Mitka, MSJ

Abstract Full Text

JAMA. 2012;308(22):2327. doi:10.1001/jama.2012.111345

Letters

Partner Violence Screening and Women’s Quality of Life

Janet Fanslow, PhD

Abstract Full Text

JAMA. 2012;308(22):2334. doi:10.1001/jama.2012.14870

Partner Violence Screening and Women’s Quality of Life

Jeremy Lazarus, MD; Jacquelyn Campbell, PhD, RN; F. David Schneider, MD, MSPH

Abstract Full Text

JAMA. 2012;308(22):2334-2336. doi:10.1001/jama.2012.14873

Partner Violence Screening and Women’s Quality of Life—Reply

Joanne Klevens, MD, PhD; Romina Kee, MD, MPH

Abstract Full Text

JAMA. 2012;308(22):2334-2336. doi:10.1001/jama.2012.14876

Partner Violence Screening and Women’s Quality of Life—Reply

Nadine Wathen, PhD; Harriet MacMillan, MD, MSc, FRCPC

Abstract Full Text

JAMA. 2012;308(22):2334-2336. doi:10.1001/jama.2012.14879

Electronic Medical Records and Hospital Progress Notes

Eugenia L. Siegler, MD

Abstract Full Text

JAMA. 2012;308(22):2336-2337. doi:10.1001/jama.2012.14495

Electronic Medical Records and Hospital Progress Notes—Reply

Robert E. Hirschtick, MD

Abstract Full Text

JAMA. 2012;308(22):2336-2337. doi:10.1001/jama.2012.14498

The Cover

Tyrol

Janet M. Torpy, MD

Abstract Full Text

JAMA. 2012;308(22):2314. doi:10.1001/jama.2012.3374

Poetry and Medicine

The Second Act

Jack Coulehan, MD

Abstract Full Text

JAMA. 2012;308(22):2316. doi:10.1001/jama.2012.13273

JAMA Patient Page

Traveling to High Altitude When You Have Sleep Apnea

Tsogyal D. Latshang, MD; Konrad E. Bloch, MD; Cassio Lynm, MA; et al.

Abstract Full Text

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JAMA. 2012;308(22):2418. doi:10.1001/jama.2012.4097

JAMA 100 Years Ago

SUGGESTION IN HYPERTHYROIDISM

Abstract Full Text

JAMA. 2012;308(22):2318. doi:10.1001/jama.2012.3375

Book and Media Reviews

Oxford Handbook of Emergency Medicine

Suzanne Dooley-Hash, MD

Abstract Full Text

JAMA. 2012;308(22):2407. doi:10.1001/jama.308.22.2407-a

Current Surgical Therapy

Daniel J. Kacey, MD

Abstract Full Text

JAMA. 2012;308(22):2407-2408. doi:10.1001/jama.308.22.2407-b

The International Traveler’s Guide to Avoiding Infections

Howard D. Backer, MD, MPH

Abstract Full Text

JAMA. 2012;308(22):2408-2409. doi:10.1001/jama.308.22.2408

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