Räber and coauthors assessed the efficacy and safety of drug-eluting stents vs bare-metal stents in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. In the related Editorial, Cassese and Kastrati discuss new-generation drug-eluting stents.
Using probability-weighted Cox proportional hazard models, Yeboah and colleagues compare the improvement of 6 risk markers for prediction of coronary heart disease on the Framingham Risk Score in 1330 intermediate-risk participants from the Multi-Ethnic Study of Atherosclerosis. In an accompanying Editorial, Gaziano and Wilson discuss cardiovascular risk assessment in the 21st century.
In an analysis of 14 cohorts, Den Ruijter and coauthors evaluated whether measuring carotid intima-media thickness improves the ability to predict the risk of cardiovascular events. In a related Editorial, Gaziano and Wilson discuss implications of these findings for patient care.
To investigate associations between statin or fibrate therapy and incident pancreatitis in large (>1000 participants) randomized trials, Preiss and coauthors conducted a meta-analysis of 21 statin trials and 7 fibrate trials.
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