Wright and coauthors examined the use of robotically assisted hysterectomy, its complication profile, and its costs compared with other routes of hysterectomy by performing a cohort study of women who underwent hysterectomy for benign gynecologic disorders from 2007 to 2010. In an Editorial, Weissman and Zinner discuss comparative effectiveness research and robotic surgery.
To determine whether shorter telomeres in leukocytes are associated with decreased resistance to upper respiratory infection and clinical illness, Cohen and coauthors assessed telomere length in peripheral blood mononuclear cells and T-cell subsets among 152 healthy participants subsequently administered rhinovirus 39 and monitored for 5 days.
Using the case of a 51-year-old woman with insomnia that began at age 35 years, Buysse reviews the assessment, diagnosis, and treatment of insomnia in adults.
Tobin and colleagues report the effectiveness of weaning patients from prolonged mechanical ventilation in a study of 312 patients at a single, long-term, acute care hospital by comparing 152 patients using pressure support vs160 with unassisted breathing through a tracheostomy. See the related Editorial by Kahn and Carson.
Zarychanski and coauthors reviewed 38 randomized controlled trials to evaluate the association of hydroxyethyl starch with mortality and renal injury in critically ill patients requiring acute volume resuscitation. In an Editorial, Antonelli and Sandroni discuss the significance of the findings in the context of conflicting studies.