To determine the relationship of regional myocardial thinning to myocardial scarring and functional improvement, Shah and coauthors assessed myocardial thinning and scarring and changes in myocardial morphology and function in patients with known coronary artery disease. Gupta and coauthors provide comment in the related Editorial.
In a large cohort study involving 59 066 participants, Winthrop and coauthors ascertained whether initiation of anti-TNF therapy compared with nonbiologic comparators was associated with increased herpes zoster risk.
Gulati and coauthors report on the association of myocardial fibrosis with mortality and sudden cardiac death in patients with nonischemic dilated cardiomyopathy. Gupta and coauthors discuss the use of cardiac magnetic resonance imaging in clinical practice.
Alford discusses the effectiveness and safety of long-term opioid therapy for chronic pain, patient assessment and education at treatment onset, and medication monitoring to ensure benefit and minimize harm.