Manson and coauthors provide an update and overview of health outcomes during the intervention and poststopping phases of the Women’s Health Initiative (WHI) hormone therapy trials. In an accompanying Editorial, Nabel discusses how the WHI is a victory for women and their health.
Raebel and colleagues compare use of opioid medications for chronic pain 1 year before bariatric surgery vs 1 year after in a retrospective cohort study of 11 719 US patients from 2005 through 2009. In an Editorial, Alford discusses risks associated with opioid use and decreasing the need for chronic opioid therapy.
To examine temporal changes in bystander resuscitation attempts and survival during a 10-year period in which several national initiatives were taken to increase rates of bystander resuscitation and improve advanced care, Wissenberg and coauthors assessed Danish Cardiac Arrest Registry records from 19 468 patients with out-of-hospital cardiac arrest.
Rao and coauthors conducted a review of the literature to summarize evidence regarding the role of axillary interventions (surgical and nonsurgical) in breast cancer treatment and to review the association of these axillary interventions with recurrence of axillary node metastases, mortality, and morbidity outcomes in patients with breast cancer.