Castro and coauthors report the effect of vitamin D3 supplementation on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels.
Neuman and coauthors investigated variations in the durability of class I guideline recommendations by the American College of Cardiology/American Heart Association by performing a textual analysis of 11 guidelines published between 1998 and 2007 and revised between 2006 and 2013. In an Editorial, Shekelle discusses the increasing importance of regularly updates to clinical practice guidelines.
In a clinical trial involving 214 patients who had disabling pain after cholecystectomy, Cotton an coauthors found that endoscopic sphincterotomy did not reduce pain any more than did a sham procedure.
Because of postsurgical risks of death, complication, and functional decline in older patients, Finlayson and colleagues conduct a review of treatment goals and evidence relating risk factors to adverse outcomes in 54 studies (encompassing 13 years) of 1 558 516 patients (aged >60 years).
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