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January 2019 - July 1883




November 12, 2014, Vol 312, No. 18, Pages 1831-1942

In This Issue of JAMA


Abstract Full Text
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JAMA. 2014;312(18):1831-1833. doi:10.1001/jama.2013.279823

Should Life Insurers Have Access to Genetic Test Results?

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JAMA. 2014;312(18):1855-1856. doi:10.1001/jama.2014.13301

This Viewpoint discusses the issues involved in granting insurance companies access to consumers’ genetic information.

Overcoming the Reimbursement Barriers for Clinical Sequencing

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JAMA. 2014;312(18):1857-1858. doi:10.1001/jama.2014.14915

This Viewpoint discusses an approach to reimbursement and coding challenges posed by next-generation genomic sequencing techniques.

The Ebola Outbreak, Fragile Health Systems, and Quality as a Cure

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JAMA. 2014;312(18):1859-1860. doi:10.1001/jama.2014.14387

This Viewpoint examines the infrastructure and quality of health systems in West Africa against the backdrop of the Ebola outbreak.

Selecting a Specialist: Adding Evidence to the Clinical Practice of Making Referrals

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JAMA. 2014;312(18):1861-1862. doi:10.1001/jama.2014.12963

This Viewpoint discusses data about consultants becoming available to referring physicians and patients in an effort to improve the selection of specialists.

A Piece of My Mind

The Quality of Mercy: Will You Be My Doctor?

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JAMA. 2014;312(18):1863-1864. doi:10.1001/jama.2014.12933

Genome-Scale Sequencing in Clinical Care: Establishing Molecular Diagnoses and Measuring Value

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JAMA. 2014;312(18):1865-1867. doi:10.1001/jama.2014.14665

This Editorial discusses possible contributions of genomic sequencing to progress in clinical care, from molecular diagnosis to improved outcomes.

Quality and Costs of End-of-Life Care: The Need for Transparency and Accountability

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JAMA. 2014;312(18):1868-1869. doi:10.1001/jama.2014.14949
Original Investigation

Molecular Findings Among Patients Referred for Clinical Whole-Exome Sequencing

Abstract Full Text
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JAMA. 2014;312(18):1870-1879. doi:10.1001/jama.2014.14601

This observation trial reports that whole-exome sequencing provides a potential molecular diagnosis for patients referred for evaluation of suspected genetic conditions, including detection of rare genetic events and new mutations, contributing to disease.

Clinical Exome Sequencing for Genetic Identification of Rare Mendelian Disorders

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JAMA. 2014;312(18):1880-1887. doi:10.1001/jama.2014.14604

Lee and coauthors report on initial clinical indications for clinical exome sequencing referrals and molecular diagnostic rates for different indications and for different test types.

Association Between the Medicare Hospice Benefit and Health Care Utilization and Costs for Patients With Poor-Prognosis Cancer

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JAMA. 2014;312(18):1888-1896. doi:10.1001/jama.2014.14950

This cohort study of patients with poor prognosis cancer receiving hospice care vs those who do not reports lower rates of hospitalization, intensive care unit admission, and invasive procedures at the end of life, along with significantly lower total costs during the last year of life.

Evaluation of the Association of Maternal Pertussis Vaccination With Obstetric Events and Birth Outcomes

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JAMA. 2014;312(18):1897-1904. doi:10.1001/jama.2014.14825

This retrospective study found that Tdap vaccination during pregnancy was not associated with increased risk of hypertensive disorders preterm or small-for-gestational age births.


Treatment of Syphilis: A Systematic Review

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JAMA. 2014;312(18):1905-1917. doi:10.1001/jama.2014.13259

This Review article concludes that the mainstay of syphilis treatment is parenteral penicillin G despite the relatively modest clinical trial data that support its use.

From the JAMA Network

Food Marketing to Youth: Serious Business

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JAMA. 2014;312(18):1918-1919. doi:10.1001/jama.2014.8951
JAMA Clinical Guidelines Synopsis

Use of HPV Vaccine in Males and Females

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JAMA. 2014;312(18):1920-1921. doi:10.1001/jama.2014.12274
JAMA Diagnostic Test Interpretation

RPR and the Serologic Diagnosis of Syphilis

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JAMA. 2014;312(18):1922-1923. doi:10.1001/jama.2014.2087
Research Letter

Life Expectancy in Patients With Chronic HCV Infection and Cirrhosis Compared With a General Population

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JAMA. 2014;312(18):1927-1928. doi:10.1001/jama.2014.12627
Medical News & Perspectives

IOM Report Calls for Transformation of End-of-Life Care

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JAMA. 2014;312(18):1845-1847. doi:10.1001/jama.2014.13254
The JAMA Forum

A To-Do List for the New CEO of the Federal Health Insurance Marketplace

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JAMA. 2014;312(18):1847-1848. doi:10.1001/jama.2014.14527
Visualizing Health Policy

Recent Trends in Employer-Sponsored Insurance

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JAMA. 2014;312(18):1849. doi:10.1001/jama.2014.13248
News From the Centers for Disease Control and Prevention

Mass Exposure to Bats at Air Force Base Leads to Group Screening

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JAMA. 2014;312(18):1851. doi:10.1001/jama.2014.14224

Vaccination Rates Among Children Remained Stable in 2013

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JAMA. 2014;312(18):1851. doi:10.1001/jama.2014.14234
Capitol Health Call

Republicans Report Disputes Between and Within Agencies Over HealthCare.gov

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JAMA. 2014;312(18):1850. doi:10.1001/jama.2014.14524

Integrating Care for Younger Disabled Does Not Improve Spending

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JAMA. 2014;312(18):1850. doi:10.1001/jama.2014.15167

Obama Signs Law to Improve Postacute Care for Medicare Patients

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JAMA. 2014;312(18):1850. doi:10.1001/jama.2014.15168

GAO: Demand for Caregiver Support Far Greater Than VA Expected

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JAMA. 2014;312(18):1850. doi:10.1001/jama.2014.15169
Comment & Response

Erythropoietin for Traumatic Brain Injury

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JAMA. 2014;312(18):1928-1929. doi:10.1001/jama.2014.12738

Erythropoietin for Traumatic Brain Injury—Reply

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JAMA. 2014;312(18):1929. doi:10.1001/jama.2014.12744

Time Since Stroke and Risk of Adverse Outcomes After Surgery

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JAMA. 2014;312(18):1930. doi:10.1001/jama.2014.13422

Time Since Stroke and Risk of Adverse Outcomes After Surgery—Reply

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JAMA. 2014;312(18):1930-1931. doi:10.1001/jama.2014.13428

Medicalization of Marijuana

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JAMA. 2014;312(18):1931. doi:10.1001/jama.2014.12563

Medicalization of Marijuana—Reply

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JAMA. 2014;312(18):1931-1932. doi:10.1001/jama.2014.12569

Incorrect Complication Description in Table

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JAMA. 2014;312(18):1932. doi:10.1001/jama.2014.14402

Typographical Errors

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JAMA. 2014;312(18):1932. doi:10.1001/jama.2014.14740

Author Missing From Byline and Additional Information

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JAMA. 2014;312(18):1932. doi:10.1001/jama.2014.8030

Incorrect Degree and Data

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JAMA. 2014;312(18):1932. doi:10.1001/jama.2014.9918
The Art of JAMA

Liberty Loan Parade: Arthur Clifton Goodwin

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JAMA. 2014;312(18):1840-1841. doi:10.1001/jama.2013.279825
Poetry and Medicine


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JAMA. 2014;312(18):1933. doi:10.1001/jama.2014.8866
JAMA Revisited

The Etiology of Syphilis

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JAMA. 2014;312(18):1935. doi:10.1001/jama.2013.279832
JAMA Patient Page

Ebola Virus Disease

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JAMA. 2014;312(18):1942. doi:10.1001/jama.2014.13759
JAMA Masthead


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JAMA. 2014;312(18):1835-1836. doi:10.1001/jama.2013.279824