Saitz and coauthors tested the efficacy of 2 brief interventions among 528 adults with unhealthy drug use identified by screening in primary care. They compared a brief negotiated interview and an intervention based on motivational interviewing with no brief intervention. In an Editorial, Hingson and Compton discuss the importance of exploring drug use with patients in primary care.
van Zanten and coauthors found that critically ill patients breathing with the aid of ventilation in intensive care units did not experience improvement in infectious complications when receiving immune-modulating nutrients compared with standard high-protein enteral nutrition.
Chung and coauthors conducted a case-control study in populations from Taiwan, Japan, and Malaysia and a genome-wide association study to investigate the genetic factors associated with phenytoin-related severe cutaneous adverse reactions.
D’Silva and coauthors assess the diagnostic accuracy of symptoms, questionnaires, and studies in the diagnosis of bladder outlet obstruction.
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