This randomized trial reports high rates of sustained virologic response in the first part of a open-label study of ombitasvir, paritaprevir (co-dosed with ritonavir), and dasabuvir with ribavirin for 63 patients with hepatitis C virus genotype 1 and human immunodeficiency virus 1 co-infection.
This pilot study reports high rates of posttreatment sustained virologic response after use of combined ledipasvir and sofosbuvir among patients co-infected with hepatitis C virus genotype 1 and human immunodeficiency virus.
This randomized controlled trial compares use of a balloon-expandable stent vs medical therapy in patients with symptomatic intracranial arterial stenosis.
This report summarizes the experience of 1 patient with needlestick exposure to the Ebola virus and postexposure vaccination with VSVΔG-ZEBOV.
This Viewpoint discusses the role of RNA interference in therapy.
This Viewpoint discusses the evolving frequency of hospital-based active shooter incidents, the relevant legal framework, and the role of hospitals and physicians in countering this threat.
This Viewpoint describes the coordination of health-related activities at the regional level through such initiatives as accountable health communities and hospital community benefit programs.
This Viewpoint discusses the potential use of combined naltrexone extended-release plus bupropion extended-release for adjunctive treatment of obesity.
This Editorial discusses the need for more randomized clinical trials to evaluate therapeutic approaches for stroke prevention in patients with intracranial arterial stenosis.
This Clinical Evidence Synopsis discusses whether oral or parenteral corticosteroids are associated with improved clinical outcomes in patients with acute sinusitis compared to placebo or standard clinical care.