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April 21, 2015, Vol 313, No. 15, Pages 1491-1584 | Child Health

In This Issue of JAMA


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JAMA. 2015;313(15):1491-1493. doi:10.1001/jama.2014.11693
Original Investigation

Effect of Parent Training vs Parent Education on Behavioral Problems in Children With Autism Spectrum Disorder: A Randomized Clinical Trial

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JAMA. 2015;313(15):1524-1533. doi:10.1001/jama.2015.3150

This randomized trial reports that a 24-week parent training program was superior to parent education for reducing disruptive behavior among children with autism spectrum disorder.

Autism Occurrence by MMR Vaccine Status Among US Children With Older Siblings With and Without Autism

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JAMA. 2015;313(15):1534-1540. doi:10.1001/jama.2015.3077

This observational cohort study reports no association between the MMR vaccine and autism spectrum disorder among US children with older siblings with autism.

Preliminary Communication

Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes: The Pre-POINT Randomized Clinical Trial

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JAMA. 2015;313(15):1541-1549. doi:10.1001/jama.2015.2928

This trial reports immune responses to insulin among children at risk for type 1 diabetes randomized to oral insulin vs placebo in an attempt to increase immune tolerance.

Outcomes Following Gene Therapy in Patients With Severe Wiskott-Aldrich Syndrome

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JAMA. 2015;313(15):1550-1563. doi:10.1001/jama.2015.3253

This case series describes the clinical outcomes of 7 patients with severe Wiskott-Aldrich syndrome who were treated with gene-corrected autologous hematopoietic stem cell transplantation.

Research Letter

Incidence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Colorado Youth, 1998-2012

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JAMA. 2015;313(15):1570-1572. doi:10.1001/jama.2015.1414

Improving Lifetime Health by Promoting Behavioral Health in Children

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JAMA. 2015;313(15):1509-1510. doi:10.1001/jama.2015.2977

This Viewpoint discusses the way that integration of behavioral health and care into early childhood primary care might improve general health outcomes for children.

Newborn Screening: Evolving Challenges in an Era of Rapid Discovery

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JAMA. 2015;313(15):1511-1512. doi:10.1001/jama.2014.17488

This Viewpoint describes the current process by which illnesses are considered for newborn screening, and the technological and other processes that may force changes to the process.

Infant HIV-1 Vaccines: Supplementing Strategies to Reduce Maternal-Child Transmission

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JAMA. 2015;313(15):1513-1514. doi:10.1001/jama.2015.1382

This Viewpoint proposes that development of an infant human immunodeficiency virus (HIV) type 1 vaccine is equally important as adult HIV-1 vaccine development to reduce maternal-child HIV transmission.

Neurotoxicity of Generic Anesthesia Agents in Infants and Children: An Orphan Research Question in Search of a Sponsor

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JAMA. 2015;313(15):1515-1516. doi:10.1001/jama.2015.1149

This Viewpoint argues that more studies and trials are needed to address questions about the optimal dose, duration, and frequency of use of anesthetic agents and vulnerable periods of exposure in young children.

A Piece of My Mind

Addie’s Hope

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JAMA. 2015;313(15):1517. doi:10.1001/jama.2014.7871

Promising Forecast for Autism Spectrum Disorders

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JAMA. 2015;313(15):1518-1519. doi:10.1001/jama.2015.2628

This Editorial discusses recent studies of factors that contribute to autism risk and of information provided to families affected by autism.

Toward Primary Prevention of Type 1 Diabetes

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JAMA. 2015;313(15):1520-1521. doi:10.1001/jama.2015.2054

This Editorial discusses the need for interventions for primary prevention of type 1 diabetes in children at genetically high risk.

An Emerging Era of Clinical Benefit From Gene Therapy

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JAMA. 2015;313(15):1522-1523. doi:10.1001/jama.2015.2055
From the JAMA Network

Fostering Early Brain Development

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JAMA. 2015;313(15):1564-1565. doi:10.1001/jama.2015.34
JAMA Clinical Challenge

An Adolescent With Right Shin Pain

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JAMA. 2015;313(15):1566-1567. doi:10.1001/jama.2014.17016
From The Medical Letter on Drugs and Therapeutics

MiniMed 530G: An Insulin Pump With Low-Glucose Suspend Automation

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JAMA. 2015;313(15):1568. doi:10.1001/jama.2015.2917

This Medical Letter review summarizes a sensor-augmented insulin pump that automatically stops delivery of insulin based on interstitial glucose levels in patients with type 1 diabetes.

Medical News & Perspectives

Why the “No-Brainer” HPV Vaccine Is Being Ignored

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JAMA. 2015;313(15):1502-1504. doi:10.1001/jama.2015.2090
News From the Food and Drug Administration

Device Approved for Some Patients With Atrial Fibrillation

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JAMA. 2015;313(15):1507. doi:10.1001/jama.2015.3001

New Chantix Warnings

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JAMA. 2015;313(15):1507. doi:10.1001/jama.2015.3305

“ResQCPR” Could Help Prevent Cardiac Arrest Deaths

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JAMA. 2015;313(15):1507. doi:10.1001/jama.2015.3307

First Biosimilar Product Approved

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JAMA. 2015;313(15):1507. doi:10.1001/jama.2015.3309
The JAMA Forum

Of Mouse and Measles

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JAMA. 2015;313(15):1504-1505. doi:10.1001/jama.2015.1135
Global Health

Diet Quality Declines Despite Increase in Healthy Food Consumption

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JAMA. 2015;313(15):1506. doi:10.1001/jama.2015.2924

Gut Bacteria Combined With Poor Diet May Promote Childhood Malnutrition

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JAMA. 2015;313(15):1506. doi:10.1001/jama.2015.3336

Report Outlines Investment Strategies for Targeting NTDs

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JAMA. 2015;313(15):1506. doi:10.1001/jama.2015.3338

Fifty Breakthroughs for Sustainable Global Development

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JAMA. 2015;313(15):1506. doi:10.1001/jama.2015.3340
The Art of JAMA

Children’s Story (Water Dreaming for Two Children): Johnny Warangkula Tjupurrula

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JAMA. 2015;313(15):1498-1499. doi:10.1001/jama.2014.11709
Poetry and Medicine


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JAMA. 2015;313(15):1576. doi:10.1001/jama.2015.439
JAMA Revisited

Immunity Against Contagious Diseases: Inadequacies

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JAMA. 2015;313(15):1577. doi:10.1001/jama.2014.11702
JAMA Patient Page

Recognizing Measles

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JAMA. 2015;313(15):1584. doi:10.1001/jama.2015.1889
Comment & Response

Surgical Treatment for Drug-Resistant Epilepsy

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JAMA. 2015;313(15):1572. doi:10.1001/jama.2015.2883

Surgical Treatment for Drug-Resistant Epilepsy—Reply

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JAMA. 2015;313(15):1572-1573. doi:10.1001/jama.2015.2886

Ethical Standards for Research Biobank Donation

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JAMA. 2015;313(15):1573-1574. doi:10.1001/jama.2015.2748

Ethical Standards for Research Biobank Donation—Reply

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JAMA. 2015;313(15):1574. doi:10.1001/jama.2015.2751

Antibiotics for Children With Acute Otitis Media

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JAMA. 2015;313(15):1574-1575. doi:10.1001/jama.2015.3080

Antibiotics for Children With Acute Otitis Media—Reply

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JAMA. 2015;313(15):1575. doi:10.1001/jama.2015.3083
JAMA Masthead


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JAMA. 2015;313(15):1495-1496. doi:10.1001/jama.2014.11694