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October 2017 - July 1883

Decade

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Issue

September 15, 2015, Vol 314, No. 11, Pages 1093-1192 | Lasker Awards at 70

In This Issue of JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2015;314(11):1093-1095. doi:10.1001/jama.2014.11977
Viewpoint

The DNA Damage Response—Self-awareness for DNAThe 2015 Albert Lasker Basic Medical Research Award

Abstract Full Text
free access
JAMA. 2015;314(11):1111-1112. doi:10.1001/jama.2015.10387

This Viewpoint discusses the the role of the DNA damage response pathway in disease syndromes and its importance to human health.

Immune Checkpoint Blockade in Cancer TherapyThe 2015 Lasker-DeBakey Clinical Medical Research Award

Abstract Full Text
JAMA. 2015;314(11):1113-1114. doi:10.1001/jama.2015.11929

In this Viewpoint, Allison discusses discoveries involving regulation of the T-cell response, development of immune checkpoint blockade in cancer therapy, and implications of engaging the immune response as a new modality for cancer treatment.

The Response to Ebola—Looking Back and Looking AheadThe 2015 Lasker-Bloomberg Public Service Award

Abstract Full Text
JAMA. 2015;314(11):1115-1116. doi:10.1001/jama.2015.11645

This Viewpoint discusses the global response to Ebola and the contributions of Médecins Sans Frontières/Doctors Without Borders to this response.

The Lasker Awards at 70

Abstract Full Text
JAMA. 2015;314(11):1117-1118. doi:10.1001/jama.2015.10116

In this Viewpoint, Pomeroy discusses the history of the Lasker Awards and their importance in highlighting the contributions of hundreds of scientists involved in research and public service.

Vaccination and the Lasker AwardsEnduring Legacies

Abstract Full Text
JAMA. 2015;314(11):1119-1120. doi:10.1001/jama.2015.9807

Dr Fauci and coauthors discuss the Lasker Awards that have been granted to scientists for discoveries underlying vaccine development.

The Lasker Awards—Recognizing and Valuing Investments in Cardiovascular Research

Abstract Full Text
JAMA. 2015;314(11):1121-1122. doi:10.1001/jama.2015.10486

This Viewpoint discusses the history of the Lasker Awards.

The Lasker Awards—Recognizing and Highlighting Oncology Research

Abstract Full Text
JAMA. 2015;314(11):1123-1124. doi:10.1001/jama.2015.10964

This commentary by JAMA Oncology Editor Mary L. Disis, MD, outlines advances in oncology through the laboratory discoveries and clinical research by Lasker Award recipients over the last 65 years.

On the Recognition of Global Excellence in Medical Research

Abstract Full Text
JAMA. 2015;314(11):1125-1126. doi:10.1001/jama.2015.10696

This commentary outlines the history and context of global prizes for health research in the years since the Albert and Mary Lasker Foundation began recognizing biomedical science and clinical research.

Scientific Discovery and the Future of Medicine

The Human Microbiome and the Future Practice of Medicine

Abstract Full Text
JAMA. 2015;314(11):1127-1128. doi:10.1001/jama.2015.10700

This Viewpoint describes early observations about the human microbiota and what research might tell us about the benefits and vulnerabilities of an individual’s microbial ecosystem.

Scientific Discovery and the Future of Medicine

Epigenetics at the Crossroads of Genes and the Environment

Abstract Full Text
JAMA. 2015;314(11):1129-1130. doi:10.1001/jama.2015.10414

This Viewpoint summarizes new trends in the field of epigenetics and epigenetic epidemiology.

A Piece of My Mind

The Joy of Discovery

Abstract Full Text
JAMA. 2015;314(11):1131-1132. doi:10.1001/jama.2015.3388
Editorial

Modern Biological Research, Medical Practice, and Human Knowledge

Abstract Full Text
JAMA. 2015;314(11):1133-1135. doi:10.1001/jama.2015.10893

Is It Possible to Recognize a Major Scientific Discovery?

Abstract Full Text
JAMA. 2015;314(11):1135-1137. doi:10.1001/jama.2015.9629

What makes a good clinical study may not be the source of a discovery that propells a medical breakthrough, but getting to to innovation may require other ways of collaboration and investigation melding ideas from many disciplines as has been highlighted in this Future of Medicine series of Viewpoints.

Prevention of Myopia in Children

Abstract Full Text
JAMA. 2015;314(11):1137-1139. doi:10.1001/jama.2015.10723

Addressing Disparities in Academic MedicineMoving Forward

Abstract Full Text
JAMA. 2015;314(11):1139-1141. doi:10.1001/jama.2015.10664
Original Investigation

Effect of Time Spent Outdoors at School on the Development of Myopia Among Children in ChinaA Randomized Clinical Trial

Abstract Full Text
free access has active quiz
JAMA. 2015;314(11):1142-1148. doi:10.1001/jama.2015.10803

This cluster randomized trial uses data collected between October 2010 and October 2013 at elementary schools in China to assess the efficacy of increasing time spent outdoors for the prevention of incident myopia in children.

Sex Differences in Academic Rank in US Medical Schools in 2014

Abstract Full Text
free access has audio
JAMA. 2015;314(11):1149-1158. doi:10.1001/jama.2015.10680

This cross-sectional comparison of databases analyzes academic faculty rank by sex in US medical schools. The analysis also looks at physician age, years since residency, specialty, authored publications, funding, and clinical trial investigation.

Outcomes After Hip Fracture Surgery Compared With Elective Total Hip Replacement

Abstract Full Text
free access has active quiz
JAMA. 2015;314(11):1159-1166. doi:10.1001/jama.2015.10842

This study determines if there was a difference in hospital mortality among patients who underwent hip fracture surgery relative to an elective total hip replacement.

From the JAMA Network

Negotiating the Tensions in Patient-Centered Care

Abstract Full Text
JAMA. 2015;314(11):1167-1168. doi:10.1001/jama.2015.10112

This commentary discusses patient-physician interactions and care quality measures in relation to a study recently published in JAMA Oncology of patients’ perception of physician compassion.

JAMA Clinical Challenge

A Growing Scar on the Abdomen of a Middle-aged Woman

Abstract Full Text
JAMA. 2015;314(11):1169-1170. doi:10.1001/jama.2015.4082

A woman in her 50s presents for evaluation of a growing, painful scar, with a bruise-like appearance at the periphery, on the right side of her abdomen; she also reports recent fevers, night sweats, nausea, and fatigue. What would you do next?

JAMA Diagnostic Test Interpretation

Thrombocytosis

Abstract Full Text
JAMA. 2015;314(11):1171-1172. doi:10.1001/jama.2015.8515

A 32-year-old woman with severe headaches had normal laboratory and neurologic results except for an elevated platelet count. What is the most likely cause for the elevated platelet count?

Research Letter

Sex Differences in Institutional Support for Junior Biomedical Researchers

Abstract Full Text
free access
JAMA. 2015;314(11):1175-1177. doi:10.1001/jama.2015.8517

This study uses application data from 2 US biomedical research programs to analyze institutional funding support for men and women overall, and by scientific focus, terminal degree, and years since receiving terminal degree.

Comment & Response

Amyloid Pathology, Cognitive Impairment, and Alzheimer Disease Risk

Abstract Full Text
JAMA. 2015;314(11):1177. doi:10.1001/jama.2015.9716

Amyloid Pathology, Cognitive Impairment, and Alzheimer Disease Risk—Reply

Abstract Full Text
JAMA. 2015;314(11):1177-1178. doi:10.1001/jama.2015.9719

Inclusion of Physicians in Bundled Hospital Payments

Abstract Full Text
JAMA. 2015;314(11):1178. doi:10.1001/jama.2015.9713

Inclusion of Physicians in Bundled Hospital Payments—Reply

Abstract Full Text
JAMA. 2015;314(11):1178-1179. doi:10.1001/jama.2015.9722
Correction

Misspelled Name

Abstract Full Text
free access
JAMA. 2015;314(11):1179. doi:10.1001/jama.2015.10276

Incorrect Spending Figure in an Editorial

Abstract Full Text
free access
JAMA. 2015;314(11):1179. doi:10.1001/jama.2015.10310

Author’s Middle Initials Missing in Byline

Abstract Full Text
free access
JAMA. 2015;314(11):1179. doi:10.1001/jama.2015.10410

Authors’ Names Reversed

Abstract Full Text
free access
JAMA. 2015;314(11):1179. doi:10.1001/jama.2015.10419
Medical News & Perspectives

Adi Nadimpalli, MD, on Doing Field Work With Doctors Without Borders

Abstract Full Text
has audio
JAMA. 2015;314(11):1103-1105. doi:10.1001/jama.2015.10442

In this Medical News & Perspectives interview, Adi Nadimpalli, MD, Doctors Without Borders/Médecins Sans Frontières (MSF) Head of Mission in Nepal, talks about the logistics and priorities of working in the field to meet the medical needs of populations in crisis.

The JAMA Forum

Finding What Works to Reduce Violence Against Women

Abstract Full Text
free access
JAMA. 2015;314(11):1105-1106. doi:10.1001/jama.2015.11233
Global Health

Outcomes of HIV Vaccine Related to Genetic Variation

Abstract Full Text
JAMA. 2015;314(11):1107. doi:10.1001/jama.2015.10553

Global Help for Post-Ebola Recovery in West Africa

Abstract Full Text
JAMA. 2015;314(11):1107. doi:10.1001/jama.2015.11110

Poor Sanitation Practices Associated With Adverse Pregnancy Outcomes

Abstract Full Text
JAMA. 2015;314(11):1107. doi:10.1001/jama.2015.11112
News From the Food and Drug Administration

The Printed Pill

Abstract Full Text
JAMA. 2015;314(11):1108. doi:10.1001/jama.2015.10976

Brain Disease Linked With MS Drug

Abstract Full Text
JAMA. 2015;314(11):1108. doi:10.1001/jama.2015.11140

Adverse Events Linked With LVADs

Abstract Full Text
JAMA. 2015;314(11):1108. doi:10.1001/jama.2015.11142

Pediatric Oxycodone

Abstract Full Text
JAMA. 2015;314(11):1108. doi:10.1001/jama.2015.11145
The Art of JAMA

Falling Stars as Seen From the BalloonAlbert Tissandier

Abstract Full Text
JAMA. 2015;314(11):1100-1101. doi:10.1001/jama.2014.11979
Poetry and Medicine

Acinar/Lepidic

Abstract Full Text
JAMA. 2015;314(11):1181. doi:10.1001/jama.2015.4351
JAMA Revisited

Lasker AwardsStatement by the Albert and Mary Lasker Foundation

Abstract Full Text
JAMA. 2015;314(11):1182. doi:10.1001/jama.2014.11986
JAMA Patient Page

Teens and Sexual Abuse

Abstract Full Text
free access
JAMA. 2015;314(11):1192. doi:10.1001/jama.2015.9938
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2015;314(11):1097-1098. doi:10.1001/jama.2014.11978
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