This Viewpoint discusses the the role of the DNA damage response pathway in disease syndromes and its importance to human health.
In this Viewpoint, Allison discusses discoveries involving regulation of the T-cell response, development of immune checkpoint blockade in cancer therapy, and implications of engaging the immune response as a new modality for cancer treatment.
This Viewpoint discusses the global response to Ebola and the contributions of Médecins Sans Frontières/Doctors Without Borders to this response.
In this Viewpoint, Pomeroy discusses the history of the Lasker Awards and their importance in highlighting the contributions of hundreds of scientists involved in research and public service.
Dr Fauci and coauthors discuss the Lasker Awards that have been granted to scientists for discoveries underlying vaccine development.
This Viewpoint discusses the history of the Lasker Awards.
This commentary by JAMA Oncology Editor Mary L. Disis, MD, outlines advances in oncology through the laboratory discoveries and clinical research by Lasker Award recipients over the last 65 years.
This commentary outlines the history and context of global prizes for health research in the years since the Albert and Mary Lasker Foundation began recognizing biomedical science and clinical research.
This Viewpoint describes early observations about the human microbiota and what research might tell us about the benefits and vulnerabilities of an individual’s microbial ecosystem.
This Viewpoint summarizes new trends in the field of epigenetics and epigenetic epidemiology.
What makes a good clinical study may not be the source of a discovery that propells a medical breakthrough, but getting to to innovation may require other ways of collaboration and investigation melding ideas from many disciplines as has been highlighted in this Future of Medicine series of Viewpoints.
This cluster randomized trial uses data collected between October 2010 and October 2013 at elementary schools in China to assess the efficacy of increasing time spent outdoors for the prevention of incident myopia in children.
This cross-sectional comparison of databases analyzes academic faculty rank by sex in US medical schools. The analysis also looks at physician age, years since residency, specialty, authored publications, funding, and clinical trial investigation.
This study determines if there was a difference in hospital mortality among patients who underwent hip fracture surgery relative to an elective total hip replacement.
This commentary discusses patient-physician interactions and care quality measures in relation to a study recently published in JAMA Oncology of patients’ perception of physician compassion.
A woman in her 50s presents for evaluation of a growing, painful scar, with a bruise-like appearance at the periphery, on the right side of her abdomen; she also reports recent fevers, night sweats, nausea, and fatigue. What would you do next?
A 32-year-old woman with severe headaches had normal laboratory and neurologic results except for an elevated platelet count. What is the most likely cause for the elevated platelet count?
This study uses application data from 2 US biomedical research programs to analyze institutional funding support for men and women overall, and by scientific focus, terminal degree, and years since receiving terminal degree.
In this Medical News & Perspectives interview, Adi Nadimpalli, MD, Doctors Without Borders/Médecins Sans Frontières (MSF) Head of Mission in Nepal, talks about the logistics and priorities of working in the field to meet the medical needs of populations in crisis.