This randomized trial determines the effect of a buffered crystalloid compared with saline on renal complications among patients in the intensive care unit.
This randomized trial compares the effects of noninvasive ventilation vs oxygen alone on 28-day mortality among immunocompromised patients with acute hypoxemic respiratory failure.
This randomized trial compares the effectiveness and safety of tiotropium vs long-acting β-agonists among black adults with asthma using inhaled corticosteroids, and determines whether polymorphisms at a locus of the β2-adrenergic receptor gene affect treatment response.
This population epidemiology study uses US National Vital Statistics System data to characterize trends in all-cause and cause-specific mortality between 1969-2013.
This study examines access to specialists in US physician networks participating in the Affordable Care Act’s insurance marketplaces in 2015.
This Viewpoint assesses the US Food and Drug Administration’s priority review voucher program to encourage development of drugs to treat neglected tropical diseases or rare pediatric disease and recommends improvements to the program.
This Viewpoint argues for regionalization of care and accompanying payment reform to improve quality and reduce the costs of caring for children with complex health care needs.
This Viewpoint proposes implementation of strategic coordinated registries networks as the foundation for a national surveillance system that inform decisions about medical device safety, effectiveness, and quality.
A 73-year-old woman presented with a widespread scaly pruritic rash lasting 2 months. She had an antinuclear antibody titer of 1:80, elevated SS-A antibodies, a creatinine level of 1.8 mg/dL, and an inflammatory pattern on skin biopsy. What would you do next?
A 47-year-old man presents with bitemporal visual field defects, low libido, and an elevated prolactin level. How do you interpret the test results?
This Medical Letter review summarizes several opioid formulations that claim to deter abuse.
This Medical News & Perspectives article describes the stroke risk associated with working too many hours and efforts to protect workers’ health as well as promote wellness.