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September 2022 - July 1883




November 3, 2015, Vol 314, No. 17, Pages 1771-1886

In This Issue of JAMA


Abstract Full Text
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JAMA. 2015;314(17):1771-1773. doi:10.1001/jama.2014.12061
Original Investigation

Efavirenz-Based Antiretroviral Therapy Among Nevirapine-Exposed HIV-Infected Children in South Africa: A Randomized Clinical Trial

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JAMA. 2015;314(17):1808-1817. doi:10.1001/jama.2015.13631

This randomized trial compares risks of viral rebound and viral failure with continuation of ritonavir-boosted lopinavir vs switching to efavirenz among children with human immunodeficiency virus (HIV) infection exposed to nevirapine for prevention of mother-to-child transmission who had initial viral suppression with ritonavir-boosted lopinavir–based therapy.

Trends in Prescription Drug Use Among Adults in the United States From 1999-2012

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JAMA. 2015;314(17):1818-1830. doi:10.1001/jama.2015.13766

This pharmacoepidemiology study uses NHANES data to describe trends in prescription drug use among US adults between 1999 and 2012.

Endovascular Thrombectomy for Acute Ischemic Stroke: A Meta-analysis

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JAMA. 2015;314(17):1832-1843. doi:10.1001/jama.2015.13767


Hospital-Diagnosed Pertussis Infection in Children and Long-term Risk of Epilepsy

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JAMA. 2015;314(17):1844-1849. doi:10.1001/jama.2015.13971

This cohort study uses Danish patient registry data to investigate associations between hospital-diagnosed pertussis infections and risk of epilepsy.

Preliminary Communication

Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans

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JAMA. 2015;314(17):1850-1860. doi:10.1001/jama.2015.13134

This article investigates mechanisms for cancer resistance in elephants and compares cellular response to DNA damage among elephants, healthy human controls, and cancer-prone patients with Li-Fraumeni syndrome.

Research Letter

Trends in Neisseria gonorrhoeae Susceptibility to Cephalosporins in the United States, 2006-2014

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JAMA. 2015;314(17):1869-1871. doi:10.1001/jama.2015.10347

This study describes gonococcal cephalosporin susceptibility trends using 2006-2014 data from the US Centers for Disease Control and Prevention (CDC) Gonococcal Isolate Surveillance Project and changes in gonorrhea treatment following publication in 2012 of a CDC treatment guideline update.

Flavored Tobacco Product Use Among US Youth Aged 12-17 Years, 2013-2014

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JAMA. 2015;314(17):1871-1873. doi:10.1001/jama.2015.13802

This national survey study characterizes self-reported use of flavored tobacco products among US youths aged 12 to 17 years in 2013 and 2014.


Confluence, Not Conflict of Interest: Name Change Necessary

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JAMA. 2015;314(17):1791-1792. doi:10.1001/jama.2015.12020

This Viewpoint discusses themes that emerged at the recent Institute for Translational Medicine and Therapeutics international meeting on conflict of interest.

New Opportunities for Integrating Drug Safety Risk Management Programs Into the Health Care System: Bridging the Divide

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JAMA. 2015;314(17):1793-1794. doi:10.1001/jama.2015.11871

This Viewpoint discusses the role of the FDA’s Risk Evaluation and Mitigation Strategies program in monitoring drug safety and proposes ways the program can be redesigned for better integration into the US health care system.

The Promotion of Medical Products in the 21st Century: Off-label Marketing and First Amendment Concerns

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JAMA. 2015;314(17):1795-1796. doi:10.1001/jama.2015.12045

This Viewpoint expresses concern over recent court-established First Amendment rights applications to the US FDA’s drug approval process.

The Undiagnosed Diseases Network of the National Institutes of Health: A National Extension

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JAMA. 2015;314(17):1797-1798. doi:10.1001/jama.2015.12249

This Viewpoint discusses the launch of the Undiagnosed Diseases Network and its features.

A Piece of My Mind

When Minutes Matter

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JAMA. 2015;314(17):1799-1800. doi:10.1001/jama.2015.9204

Antiretroviral Therapy for Nevirapine-Exposed Children With HIV Infection

Abstract Full Text
JAMA. 2015;314(17):1801-1802. doi:10.1001/jama.2015.13763

Thrombectomy for Acute Ischemic Stroke

Abstract Full Text
JAMA. 2015;314(17):1803-1805. doi:10.1001/jama.2015.14674

Evolutionary Adaptations to Risk of Cancer: Evidence From Cancer Resistance in Elephants

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JAMA. 2015;314(17):1806-1807. doi:10.1001/jama.2015.13153
From the JAMA Network

Diabetes Risk Assessment and Glycemic Control

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JAMA. 2015;314(17):1861-1862. doi:10.1001/jama.2015.11518

This commentary discusses a cluster randomized trial published in JAMA Ophthalmology that compared the effects of personalized education and risk assessment vs usual care during retinal ophthalmologic visits on hemoglobin A1c levels among patients with diabetes.

JAMA Clinical Evidence Synopsis

Interventions for Hirsutism

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JAMA. 2015;314(17):1863-1864. doi:10.1001/jama.2015.11743

This Clinical Evidence Synopsis summarizes a Cochrane review on interventions for hirsutism.

JAMA Clinical Guidelines Synopsis

Evaluation of Patients With Asymptomatic Microhematuria

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JAMA. 2015;314(17):1865-1866. doi:10.1001/jama.2015.13711

This JAMA Clinical Guidelines Synopsis summarizes the American Urological Association’s 2012 guideline for evaluating patients with asymptomatic microhematuria.

Medical News & Perspectives

Transgender Care Moves Into the Mainstream

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JAMA. 2015;314(17):1785-1787. doi:10.1001/jama.2015.11043

This Medical News and Perspectives article discusses the barriers that transgender patients encounter in seeking health care and the resources and education available to physicians.

News From the Food and Drug Administration

Expanding the Diabetes Arsenal

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JAMA. 2015;314(17):1789. doi:10.1001/jama.2015.13699

New Atypical Antipsychotic

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JAMA. 2015;314(17):1789. doi:10.1001/jama.2015.14005

Can You Hear Me Now?

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JAMA. 2015;314(17):1789. doi:10.1001/jama.2015.14007

One More Option for Advanced Colorectal Cancer

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JAMA. 2015;314(17):1789. doi:10.1001/jama.2015.14009
Lab Reports

Adipose Tissue: An HIV Reservoir With Inflammatory Potential

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JAMA. 2015;314(17):1788. doi:10.1001/jama.2015.13106

Implantable Device Attracts and Captures Early Metastatic Cells

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JAMA. 2015;314(17):1788. doi:10.1001/jama.2015.13931

Plasma DNA Mapping May Have Broad Clinical Application

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JAMA. 2015;314(17):1788. doi:10.1001/jama.2015.13933

Tackling Breast Cancers Resistant to Hormone Therapy

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JAMA. 2015;314(17):1788. doi:10.1001/jama.2015.13935
The Art of JAMA

Panic: Nikolay Viting

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JAMA. 2015;314(17):1780-1781. doi:10.1001/jama.2014.12063
Poetry and Medicine


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JAMA. 2015;314(17):1877. doi:10.1001/jama.2015.4353
JAMA Revisited

Knowledge and Wisdom in Medicine

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JAMA. 2015;314(17):1878. doi:10.1001/jama.2014.12070
JAMA Patient Page

Bladder Cancer

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JAMA. 2015;314(17):1886. doi:10.1001/jama.2015.13738
Comment & Response

Use of Implantable Cardioverter-Defibrillators Among Medicare Patients

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JAMA. 2015;314(17):1873-1874. doi:10.1001/jama.2015.12212

Use of Implantable Cardioverter-Defibrillators Among Medicare Patients—Reply

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JAMA. 2015;314(17):1874-1875. doi:10.1001/jama.2015.12218

Risk Prediction for Individuals

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JAMA. 2015;314(17):1875. doi:10.1001/jama.2015.12215

Risk Prediction for Individuals—Reply

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JAMA. 2015;314(17):1875-1876. doi:10.1001/jama.2015.12221
JAMA Masthead


Abstract Full Text
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JAMA. 2015;314(17):1775-1776. doi:10.1001/jama.2014.12062