This randomized clinical trial evaluates the effects of ovarian suppression using the luteinizing hormone–releasing hormone analogue triptorelin on long-term ovarian function, pregnancies, and disease-free survival among premenopausal women receiving adjuvant breast cancer chemotherapy.
This 2×2 factorial randomized trial compares the effects of larger vs smaller chest tube size and nonsteroidal anti-inflammatory drugs vs opiates on pain and efficacy of pleurodesis in patients with malignant pleural effusion.
This study uses national United Kingdom in vitro fertilization (IVF) data to investigate the live-birth rate per IVF cycle and cumulative live-birth rate across all cycles by women’s age and treatment type between 2003 and 2010.
This case series describes the clinical characteristics and natural course of patients with acute flaccid paralysis reported to the California Department of Public Health between June 2012 and July 2015, and compares case incidence during a US enterovirus D68 outbreak with other monitoring periods.
This study uses data from the Surveillance, Epidemiology, and End Results database to examine the association between access to paid sick leave and job retention and personal financial burden among patients with colorectal cancer.
This Viewpoint discusses the importance of including physical activity counseling in patient encounters and provides tools for efficiently integrating this activity into busy clinical settings.
This Viewpoint discusses aspects of the one-child policy in China and speculates on the future of the population with the newly announced two-child policy.
This Viewpoint discusses financial, political, and practical challenges to realizing the United Nations’ 2015 Sustainable Development Goals.
This Rational Clinical Examination systematic review summarizes the accuracy of symptoms and signs for revealing severe intracranial injury in adults with minor head trauma.
This commentary discusses a study published in JAMA Ophthalmology that describes the accuracy of a smartphone-based visual acuity test for detecting visual impairment in rural Kenya.
This JAMA Clinical Guidelines Synopsis summarizes the American Gastroenterological Association’s 2014 guideline on pharmacologic management of irritable bowel syndrome.
This Medical News and Perspectives piece recounts the 30-year history of the AIDS Clinical Trials Group, detailing the many challenges and obstacles along the road to developing an effective treatment against HIV.