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May 2023 - July 1883




August 25, 2015, Vol 314, No. 8, Pages 747-850

In This Issue of JAMA


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JAMA. 2015;314(8):747-749. doi:10.1001/jama.2014.11935
Original Investigation

Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial

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JAMA. 2015;314(8):781-790. doi:10.1001/jama.2015.9617

This randomized trial assessed the effects of a 24-month physical activity program on cognitive function, mild cognitive impairment, and dementia compared with a health education program in sedentary adults aged 70 to 89 years.

Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial

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JAMA. 2015;314(8):791-801. doi:10.1001/jama.2015.9677

This randomized trial reports that among older individuals with age-related macular degeneration supplements containing long-chain fatty acids and/or lutein and zeaxanthin had no effect on cognitive function.

Caring for the Critically Ill Patient

Time to Epinephrine and Survival After Pediatric In-Hospital Cardiac Arrest

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JAMA. 2015;314(8):802-810. doi:10.1001/jama.2015.9678

This study uses data for pediatric patients from the Get With the Guidelines–Resuscitation registry to report associations between delay in epinephrine and survival and neurological outcome after pediatric in-hospital cardiac arrest.

Preliminary Communication

Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia

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JAMA. 2015;314(8):811-822. doi:10.1001/jama.2015.9643

This cohort study investigates clearance patterns of somatic mutations in acute myeloid leukemia patients given induction chemotherapy, and associations between those patterns and clinical outcomes.

Research Letter

Military Misconduct and Homelessness Among US Veterans Separated From Active Duty, 2001-2012

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JAMA. 2015;314(8):832-834. doi:10.1001/jama.2015.8207

This study used Veterans Health Administration data to investigate the association between misconduct-related separations and homelessness among recently returned active-duty US military service members.


Sexual Health in America: Improving Patient Care and Public Health

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JAMA. 2015;314(8):765-766. doi:10.1001/jama.2015.6831

This Viewpoint discusses a framework for improving patient care and public sexual health.

Fusing Randomized Trials With Big Data: The Key to Self-learning Health Care Systems?

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JAMA. 2015;314(8):767-768. doi:10.1001/jama.2015.7762

This Viewpoint proposes ways that electronic health records and other “big data” can be integrated with randomized trial designs to leverage the strengths of both for research inferences.

Quality Indicators for Physical and Behavioral Health Care Integration

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JAMA. 2015;314(8):769-770. doi:10.1001/jama.2015.6447

This Viewpoint discusses developing quality metrics in behavioral and general health care to encourage more cost-effective care and improve the status quo.

Middle East Respiratory Syndrome: A Global Health Challenge

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JAMA. 2015;314(8):771-772. doi:10.1001/jama.2015.7646

This Viewpoint discusses the importance of a well-trained and well-prepared health workforce in controlling outbreaks such as Middle East respiratory syndrome.

A Piece of My Mind

The “Good Person” Sign

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JAMA. 2015;314(8):773. doi:10.1001/jama.2015.4890

Lifestyles and Cognitive Health: What Older Individuals Can Do to Optimize Cognitive Outcomes

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JAMA. 2015;314(8):774-775. doi:10.1001/jama.2015.9526

Pediatric Pulseless Arrest With “Nonshockable” Rhythm: Does Faster Time to Epinephrine Improve Outcome?

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JAMA. 2015;314(8):776-777. doi:10.1001/jama.2015.9527

Next-Generation Sequencing and Detection of Minimal Residual Disease in Acute Myeloid Leukemia: Ready for Clinical Practice?

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JAMA. 2015;314(8):778-780. doi:10.1001/jama.2015.9452
From the JAMA Network

Engaging Primary Care Clinicians in Early Obesity Prevention Research

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JAMA. 2015;314(8):823-824. doi:10.1001/jama.2015.6262

This commentary describes a report published in JAMA Pediatrics summarizing a National Institutes of Health workshop about primary care clinician involvement in preventing early childhood obesity.

JAMA Clinical Guidelines Synopsis

Prostate Cancer Screening

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JAMA. 2015;314(8):825-826. doi:10.1001/jama.2015.8033

This JAMA Clinical Guidelines Synopsis summarizes the US Preventive Services Task Force’s (2012) and American Urological Association’s (2013) clinical practice guidelines for prostate cancer screening.

JAMA Diagnostic Test Interpretation

Clinical Significance of a Positive Antinuclear Antibody Test

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JAMA. 2015;314(8):827-828. doi:10.1001/jama.2015.7649

A 30-year-old woman with polyarthralgias responsive to celecoxib has an ANA titer of 1:80. How do you interpret this test result?

Medical News & Perspectives

Questions of Safety and Fairness Raised as Right-to-Try Movement Gains Steam

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JAMA. 2015;314(8):758-760. doi:10.1001/jama.2015.7691

This Medical News and Perspectives article discusses issues surrounding Right-to-Try laws that allow patients with terminal illness to petition for access to investigational drugs and therapies.

News From the Centers for Disease Control and Prevention

Rapid US Response to Ebola Threat

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JAMA. 2015;314(8):763. doi:10.1001/jama.2015.9791

More Health Advice Needed to Cut US Sodium Intake

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JAMA. 2015;314(8):763. doi:10.1001/jama.2015.9917
Clinical Trials Update

Diabetes Remission 3 Years After Bariatric Surgery

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JAMA. 2015;314(8):762. doi:10.1001/jama.2015.9172

Diabetes Drug Helps Promote Weight Loss in Obese Patients

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JAMA. 2015;314(8):762. doi:10.1001/jama.2015.9949

Bridging Anticoagulation Offers No Perioperative Benefit

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JAMA. 2015;314(8):762. doi:10.1001/jama.2015.9951
Health Agencies Update

Recommendations to Improve Cardiac Arrest Survival

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JAMA. 2015;314(8):761. doi:10.1001/jama.2015.9168

CMS Proposes Payment for Advance Care Planning Discussions

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JAMA. 2015;314(8):761. doi:10.1001/jama.2015.9962

HHS Establishes Training and Education Center for Ebola

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JAMA. 2015;314(8):761. doi:10.1001/jama.2015.9966
The Art of JAMA

Mahabalipooram: Edward Lear

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JAMA. 2015;314(8):754-755. doi:10.1001/jama.2014.11937
Poetry and Medicine


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JAMA. 2015;314(8):838. doi:10.1001/jama.2015.6697
JAMA Revisited

The House: Its Unique Problems in Hygiene

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JAMA. 2015;314(8):839. doi:10.1001/jama.2014.11944
JAMA Patient Page

Childhood Obesity

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JAMA. 2015;314(8):850. doi:10.1001/jama.2015.6674
Comment & Response

Opioid Dependence Treatment in the Emergency Department

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JAMA. 2015;314(8):834-835. doi:10.1001/jama.2015.8519

Opioid Dependence Treatment in the Emergency Department—Reply

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JAMA. 2015;314(8):835. doi:10.1001/jama.2015.8527

Etiologies of Tattoo Lesions

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JAMA. 2015;314(8):836. doi:10.1001/jama.2015.8986

Etiologies of Tattoo Lesions—Reply

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JAMA. 2015;314(8):836-837. doi:10.1001/jama.2015.8989

Lines Omitted From Table

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JAMA. 2015;314(8):837. doi:10.1001/jama.2015.10005

Incorrect Values Reported

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JAMA. 2015;314(8):837. doi:10.1001/jama.2015.9010

Incorrect Study Name

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JAMA. 2015;314(8):837. doi:10.1001/jama.2015.9181
JAMA Masthead


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JAMA. 2015;314(8):751-752. doi:10.1001/jama.2014.11936