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May 2023 - July 1883




September 1, 2015, Vol 314, No. 9, Pages 853-964

In This Issue of JAMA


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JAMA. 2015;314(9):853-855. doi:10.1001/jama.2014.11949
Original Investigation

Effect of Finerenone on Albuminuria in Patients With Diabetic Nephropathy: A Randomized Clinical Trial

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JAMA. 2015;314(9):884-894. doi:10.1001/jama.2015.10081

This randomized trial compares the safety and effects of finerenone, a nonsteroidal mineralocorticoid receptor antagonist, on albuminuria in patients with diabetic nephropathy already taking renin-angiotensin blockers.

Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder

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JAMA. 2015;314(9):895-903. doi:10.1001/jama.2015.10078

This case series of children with autism spectrum disorder compares the diagnostic yield of chromosomal microarray analysis vs whole-exome sequencing.

Association Between Blood Pressure Control and Risk of Recurrent Intracerebral Hemorrhage

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JAMA. 2015;314(9):904-912. doi:10.1001/jama.2015.10082

This cohort study reports that among patients with a first episode of intracranial hemorrhage (ICH), inadequate blood pressure control was associated with higher risk of recurrence of ICH.

Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth

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JAMA. 2015;314(9):913-925. doi:10.1001/jama.2015.10080

This case series involving children and young adults with cancer whose genomic sequencing results were the basis for clinical case recommendations charaterizes the number of clinically actionable findings and resulting patient outcomes.

Research Letter

Bicycle Trauma Injuries and Hospital Admissions in the United States, 1998-2013

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JAMA. 2015;314(9):947-949. doi:10.1001/jama.2015.8295

This study uses National Electronic Injury Surveillance System data to describe trends in adult cycling injuries and related hospital admissions in the United States.


Evaluation of Flibanserin: Science and Advocacy at the FDA

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JAMA. 2015;314(9):869-870. doi:10.1001/jama.2015.8405

This Viewpoint discusses the history of flibanserin and provides insight about the regulatory process.

Specialty Society Clinical Practice Guidelines: Time for Evolution or Revolution?

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JAMA. 2015;314(9):871-872. doi:10.1001/jama.2015.7462

This Viewpoint discusses challenges of developing and implementing clinical practice guidelines.

Body-Fixed Sensors for Parkinson Disease

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JAMA. 2015;314(9):873-874. doi:10.1001/jama.2015.8530

This Viewpoint discusses the use of body-fixed sensors to accurately track disease status and the effect of treatment in patients with Parkinson disease.

Learning From the Past to Measure the Future

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JAMA. 2015;314(9):875-876. doi:10.1001/jama.2015.9186

This Viewpoint, from the current CEO of the National Quality Forum and the director of AHRQ, discusses the changes in health care quality measurement over the past 15 years and opportunities for future progress.

A Piece of My Mind


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JAMA. 2015;314(9):877-878. doi:10.1001/jama.2015.2146

Complex Autism Spectrum Disorders and Cutting-Edge Molecular Diagnostic Tests

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JAMA. 2015;314(9):879-880. doi:10.1001/jama.2015.9577

Improving Patient Outcomes With Cancer Genomics: Unique Opportunities and Challenges in Pediatric Oncology

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JAMA. 2015;314(9):881-883. doi:10.1001/jama.2015.9794

Medical Therapies for Adult Chronic Sinusitis: A Systematic Review

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JAMA. 2015;314(9):926-939. doi:10.1001/jama.2015.7544

This systematic review summarizes the evidence-based medical treatment of adult chronic sinusitis and propses a treatment algorithm.

JAMA Guide to Statistics and Methods

Missing Data: How to Best Account for What Is Not Known

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JAMA. 2015;314(9):940-941. doi:10.1001/jama.2015.10516

This Guide to Statistics and Methods characterizes the strengths and limitations of different approaches for modeling missing data in clinical research using the example of a trial that applied several of these techniques.

JAMA Clinical Challenge

Diplopia and Ataxia in a Heavy Smoker

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JAMA. 2015;314(9):942-943. doi:10.1001/jama.2015.8617

A 64-year-old man with coronary artery disease and an 80 pack-year smoking habit presented with vertigo, diplopia, ataxia, cranial nerve palsy findings, and pulmonary nodules with mediastinal lymphadenopathy on CT. What would you do next?

Medical News & Perspectives

As New Orleans Looks to the Future, Questions Remain on Hurricane Katrina’s Long-term Mental Health Effects

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JAMA. 2015;314(9):863-865. doi:10.1001/jama.2015.9797

This Medical News & Perspectives article looks at the long-term mental health effects of Hurricane Katrina 10 years after the disaster.

News From the Food and Drug Administration

Nonsurgical Weight Loss Device

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JAMA. 2015;314(9):867. doi:10.1001/jama.2015.10199

New Drug to Lower LDL Cholesterol

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JAMA. 2015;314(9):867. doi:10.1001/jama.2015.10491

Treatment for HCV Genotypes 3 and 4

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JAMA. 2015;314(9):867. doi:10.1001/jama.2015.10492
Lab Reports

Antibody Therapy Blocks Effects of Traumatic Brain Injury

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JAMA. 2015;314(9):866. doi:10.1001/jama.2015.10605

Organoids Help Uncover Possible Mechanisms of Autism

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JAMA. 2015;314(9):866. doi:10.1001/jama.2015.10607

Lipid Molecules May Help Improve Bone Marrow Engraftment

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JAMA. 2015;314(9):866. doi:10.1001/jama.2015.10608

Novel, Long-Acting Drug May Help Prevent and Treat Malaria

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JAMA. 2015;314(9):866. doi:10.1001/jama.2015.9802
The Art of JAMA

Gasometers: Cyril E. Power

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JAMA. 2015;314(9):860-861. doi:10.1001/jama.2014.11951
Poetry and Medicine

In the Meantime, Life

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JAMA. 2015;314(9):953. doi:10.1001/jama.2015.5885
JAMA Revisited

What’s in a Name?

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JAMA. 2015;314(9):954. doi:10.1001/jama.2014.11958
JAMA Patient Page

Adult Chronic Sinusitis

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JAMA. 2015;314(9):964. doi:10.1001/jama.2015.7892
Comment & Response

Assessing Eligibility for Anticoagulation After Diagnosis of Atrial Fibrillation

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JAMA. 2015;314(9):949. doi:10.1001/jama.2015.8992

Assessing Eligibility for Anticoagulation After Diagnosis of Atrial Fibrillation—Reply

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JAMA. 2015;314(9):949-950. doi:10.1001/jama.2015.8995

Trends in Prevalence of the Metabolic Syndrome

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JAMA. 2015;314(9):950. doi:10.1001/jama.2015.8625

Trends in Prevalence of the Metabolic Syndrome—Reply

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JAMA. 2015;314(9):950-951. doi:10.1001/jama.2015.8628

Maintenance of Certification and the Interstate Medical Licensure Compact

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JAMA. 2015;314(9):951-952. doi:10.1001/jama.2015.8906

Maintenance of Certification Programs and the Interstate Medical Licensure Compact—Reply

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JAMA. 2015;314(9):952. doi:10.1001/jama.2015.8912

Clarification About Lower-Cost Drug

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JAMA. 2015;314(9):952. doi:10.1001/jama.2015.9906
JAMA Masthead


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JAMA. 2015;314(9):857-858. doi:10.1001/jama.2014.11950