This randomized trial compares the safety and effects of finerenone, a nonsteroidal mineralocorticoid receptor antagonist, on albuminuria in patients with diabetic nephropathy already taking renin-angiotensin blockers.
This case series of children with autism spectrum disorder compares the diagnostic yield of chromosomal microarray analysis vs whole-exome sequencing.
This cohort study reports that among patients with a first episode of intracranial hemorrhage (ICH), inadequate blood pressure control was associated with higher risk of recurrence of ICH.
This case series involving children and young adults with cancer whose genomic sequencing results were the basis for clinical case recommendations charaterizes the number of clinically actionable findings and resulting patient outcomes.
This study uses National Electronic Injury Surveillance System data to describe trends in adult cycling injuries and related hospital admissions in the United States.
This Viewpoint discusses the history of flibanserin and provides insight about the regulatory process.
This Viewpoint discusses challenges of developing and implementing clinical practice guidelines.
This Viewpoint discusses the use of body-fixed sensors to accurately track disease status and the effect of treatment in patients with Parkinson disease.
This Viewpoint, from the current CEO of the National Quality Forum and the director of AHRQ, discusses the changes in health care quality measurement over the past 15 years and opportunities for future progress.
This systematic review summarizes the evidence-based medical treatment of adult chronic sinusitis and propses a treatment algorithm.
This Guide to Statistics and Methods characterizes the strengths and limitations of different approaches for modeling missing data in clinical research using the example of a trial that applied several of these techniques.
A 64-year-old man with coronary artery disease and an 80 pack-year smoking habit presented with vertigo, diplopia, ataxia, cranial nerve palsy findings, and pulmonary nodules with mediastinal lymphadenopathy on CT. What would you do next?
This Medical News & Perspectives article looks at the long-term mental health effects of Hurricane Katrina 10 years after the disaster.
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