This randomized clinical trial determines whether diet or exercise improves exercise capacity and quality of life among obese older patients with heart failure with preserved ejection fraction (HFPEF).
This prospective cohort study investigates the association of rare, potentially pathogenic variants in 2 cardiac arrhythmia susceptibility genes with arrhythmia and electrocardiographic phenotypes using electronic medical record data.
This nationwide, register-based, matched-cohort study evaluates the potential association between fluconazole exposure during pregnancy and risk of spontaneous abortion and stillbirth among women in Denmark.
This study estimates familial risk and heritability of cancer types in a large twin cohort using data from population-based registers in Denmark, Finland, Norway, and Sweden.
This cohort study uses data from the US National Child Abuse and Neglect Data System to examine the incidence and timing of re-referral of children with disabilities to child protective services after an initial referral for neglect in fiscal years 2008 through 2012.
This Viewpoint proposes requirements for smartphone paging applications that facilitate team-based care and replace conventional pager systems.
This Viewpoint discusses health care delivery models intended to improve the continuity of inpatient and outpatient care for high-risk older patients.
This Viewpoint discusses the importantance of developing effective mechanisms for reconciling differences that emerge when information accrual from genetic animal models outpace the data collection from patients enrolled in clinical trials.
This commentary discusses a cost-effectiveness study published in JAMA Oncology that found CT screening for lung cancer would be cost-effective in a Canadian population.
A 75-year-old woman with rheumatoid arthritis and genital herpes simplex virus 2 presented with painful, pruritic plaques on her buttock. She denied recent trauma to the area, skin exposures, fever, or lymphadenopathy. She takes prednisone, pregabalin, and valacyclovir. What would you do next?
An asymptomatic 23-year-old woman with dental enamel defects and a family history of celiac disease presented for assessment of positive celiac disease serologic testing. How do you interpret the test results?
This Medical News & Perspectives article examines new recommendations on nonhormonal management of vasomotor symptoms associated with menopause.