This genetic epidemiology study uses mendelian randomization to investigate associations between maternal body mass index and glucose and lipid levels and offspring birth weight between 1929 and 2013.
This study uses text mining analysis of MEDLINE and PubMed Central abstracts to characterize trends and patterns of P value and other statistical reporting since 1990.
This randomized clinical trial compares the effect of hypothermia with vs without xenon on magnetic resonance imaging–assessed white matter damage in comatose patients who had experienced out-of-hospital cardiac arrest in Finland.
This study examines the association between implementation of a Centers for Medicare & Medicaid Services policy mandating suppression of substance abuse–related claims in Medicare and Medicaid Research Identifiable Files and rates of diagnoses for non–substance abuse conditions in those data.
This Viewpoint discusses the need to examine how perceptions of the country of origin may of health care innovations proposed for US settings may influence diffusion of these innovations.
This Viewpoint discusses the benefits and challenges of implementing the US Department of Housing and Urban Development’s proposed rule to ensure smoke-free environments for residents of federally assisted public housing.
This Viewpoint describes the rationale behind an FDA and NIH effort to develop a glossary of common terms and definitions for biomarkers and surrogate endpoints.
This Viewpoint discusses the use of bundled payment programs organized around procedures or diseases as a means of addressing the challenges of implementing integrated models of health care delivery.
This evidence review summarizes published reports of measles and pertussis outbreaks to characterize associations with vaccine delay, vaccine refusal, and waning immunity.
A 61-year-old man with hypertension, type 2 diabetes, and hypothyroidism presented with neck pain and stiffness and woody induration extending from the nape of his neck. Examination of his heart, lungs, abdomen, and lower extremities was normal, as was serum albumin level. What would you do next?
This Medical Letter review summarizes information about liraglutide, a GLP-1 receptor agonist approved for long-term weight weight management in adults with a body mass index (BMI) of 30 or greater, or in those with a BMI of 27 or greater plus weight-related comorbidity such as hypertension, dyslipidemia, or diabetes.
This Medical News & Perspectives article explores current and planned research into the once-obscure Zika virus, which has swept into more than 20 countries and is associated with a steep increase in cases of microcephaly.