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May 2023 - July 1883




March 15, 2016, Vol 315, No. 11, Pages 1077-1196

In This Issue of JAMA


Abstract Full Text
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JAMA. 2016;315(11):1077-1079. doi:10.1001/jama.2015.14162
Original Investigation

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

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JAMA. 2016;315(11):1129-1140. doi:10.1001/jama.2016.1975

This genetic epidemiology study uses mendelian randomization to investigate associations between maternal body mass index and glucose and lipid levels and offspring birth weight between 1929 and 2013.

Evolution of Reporting P Values in the Biomedical Literature, 1990-2015

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JAMA. 2016;315(11):1141-1148. doi:10.1001/jama.2016.1952

This study uses text mining analysis of MEDLINE and PubMed Central abstracts to characterize trends and patterns of P value and other statistical reporting since 1990.

Preliminary Communication

Caring for the Critically Ill Patient

Effect of Inhaled Xenon on Cerebral White Matter Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial

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JAMA. 2016;315(11):1120-1128. doi:10.1001/jama.2016.1933

This randomized clinical trial compares the effect of hypothermia with vs without xenon on magnetic resonance imaging–assessed white matter damage in comatose patients who had experienced out-of-hospital cardiac arrest in Finland.

Research Letter

Suppression of Substance Abuse Claims in Medicaid Data and Rates of Diagnoses for Non–Substance Abuse Conditions

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JAMA. 2016;315(11):1164-1166. doi:10.1001/jama.2015.18417

This study examines the association between implementation of a Centers for Medicare & Medicaid Services policy mandating suppression of substance abuse–related claims in Medicare and Medicaid Research Identifiable Files and rates of diagnoses for non–substance abuse conditions in those data.


Innovations in Health Care Delivery

Does the Country of Origin Matter in Health Care Innovation Diffusion?

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JAMA. 2016;315(11):1103-1104. doi:10.1001/jama.2016.0483

This Viewpoint discusses the need to examine how perceptions of the country of origin may of health care innovations proposed for US settings may influence diffusion of these innovations.

The Proposal for Smoke-Free Public Housing: Benefits, Challenges, and Opportunities for 2 Million Residents

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JAMA. 2016;315(11):1105-1106. doi:10.1001/jama.2016.1380

This Viewpoint discusses the benefits and challenges of implementing the US Department of Housing and Urban Development’s proposed rule to ensure smoke-free environments for residents of federally assisted public housing.

Biomarkers and Surrogate Endpoints: Developing Common Terminology and Definitions

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JAMA. 2016;315(11):1107-1108. doi:10.1001/jama.2016.2240

This Viewpoint describes the rationale behind an FDA and NIH effort to develop a glossary of common terms and definitions for biomarkers and surrogate endpoints.

Health Care Delivery Innovations That Integrate Care? Yes!But Integrating What?

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JAMA. 2016;315(11):1109-1110. doi:10.1001/jama.2016.0505

This Viewpoint discusses the use of bundled payment programs organized around procedures or diseases as a means of addressing the challenges of implementing integrated models of health care delivery.

A Piece of My Mind

Meeting the Organ Donor

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JAMA. 2016;315(11):1111-1112. doi:10.1001/jama.2015.18357

The Enduring Evolution of the P Value

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JAMA. 2016;315(11):1113-1115. doi:10.1001/jama.2016.2152

Toward High-Reliability Vaccination Efforts in the United States

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JAMA. 2016;315(11):1115-1117. doi:10.1001/jama.2016.1529

To JAMA Peer Reviewers, Authors, and Readers—Thank You

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JAMA. 2016;315(11):1118-1119. doi:10.1001/jama.2016.2422

Association Between Vaccine Refusal and Vaccine-Preventable Diseases in the United States: A Review of Measles and Pertussis

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JAMA. 2016;315(11):1149-1158. doi:10.1001/jama.2016.1353

This evidence review summarizes published reports of measles and pertussis outbreaks to characterize associations with vaccine delay, vaccine refusal, and waning immunity.

JAMA Clinical Challenge

Neck Pain, Stiffness, and Periorbital Edema in a Man With Diabetes

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JAMA. 2016;315(11):1159-1160. doi:10.1001/jama.2016.1770

A 61-year-old man with hypertension, type 2 diabetes, and hypothyroidism presented with neck pain and stiffness and woody induration extending from the nape of his neck. Examination of his heart, lungs, abdomen, and lower extremities was normal, as was serum albumin level. What would you do next?

From The Medical Letter on Drugs and Therapeutics

Liraglutide (Saxenda) for Weight Loss

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JAMA. 2016;315(11):1161-1162. doi:10.1001/jama.2016.2083

This Medical Letter review summarizes information about liraglutide, a GLP-1 receptor agonist approved for long-term weight weight management in adults with a body mass index (BMI) of 30 or greater, or in those with a BMI of 27 or greater plus weight-related comorbidity such as hypertension, dyslipidemia, or diabetes.

Medical News & Perspectives

Researchers Focus on Solving the Zika Riddles

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JAMA. 2016;315(11):1097-1099. doi:10.1001/jama.2016.1219

This Medical News & Perspectives article explores current and planned research into the once-obscure Zika virus, which has swept into more than 20 countries and is associated with a steep increase in cases of microcephaly.

News From the Food and Drug Administration

New Attempt to Curb Opioid Abuse

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JAMA. 2016;315(11):1101. doi:10.1001/jama.2016.2034

Combination Treatment for HCV

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JAMA. 2016;315(11):1101. doi:10.1001/jama.2016.2070

Funding the Cancer Moonshot

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JAMA. 2016;315(11):1101. doi:10.1001/jama.2016.2072
Global Health

Deforestation Clears Way for Zoonotic Malaria in Malaysia

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JAMA. 2016;315(11):1100. doi:10.1001/jama.2016.1702

Rates of Youth Obesity Increase Around the World

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JAMA. 2016;315(11):1100. doi:10.1001/jama.2016.2263

Antibiotics of No Benefit in Treating Children With Malnutrition

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JAMA. 2016;315(11):1100. doi:10.1001/jama.2016.2266
The Art of JAMA

The Lost Felice: Marsden Hartley

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JAMA. 2016;315(11):1088-1089. doi:10.1001/jama.2015.14164
Poetry and Medicine


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JAMA. 2016;315(11):1171. doi:10.1001/jama.2015.17373
JAMA Revisited

Reducing Medical Facilities

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JAMA. 2016;315(11):1172. doi:10.1001/jama.2015.17078
Peer Reviewers List

JAMA Peer Reviewers in 2015

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JAMA. 2016;315(11):1175-1189. doi:10.1001/jama.2016.0425
JAMA Patient Page

Dietary Guidelines for Americans—Eat Less Sugar

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JAMA. 2016;315(11):1196. doi:10.1001/jama.2016.0968
Comment & Response

Dextromethorphan-Quinidine for Agitation in Alzheimer Disease

Abstract Full Text
JAMA. 2016;315(11):1166. doi:10.1001/jama.2015.18286

Dextromethorphan-Quinidine for Agitation in Alzheimer Disease—Reply

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JAMA. 2016;315(11):1166. doi:10.1001/jama.2015.18289

Preeclampsia and Congenital Heart Defects

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JAMA. 2016;315(11):1167-1168. doi:10.1001/jama.2015.19075

Preeclampsia and Congenital Heart Defects—Reply

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JAMA. 2016;315(11):1168-1169. doi:10.1001/jama.2015.19084

New Strategies to Treat High Cholesterol

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JAMA. 2016;315(11):1169. doi:10.1001/jama.2015.18029

New Strategies to Treat High Cholesterol—Reply

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JAMA. 2016;315(11):1169-1170. doi:10.1001/jama.2015.18038
JAMA Masthead


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JAMA. 2016;315(11):1081-1082. doi:10.1001/jama.2015.14163