This prospective study sought to determine the incidence, risk factors, and attributable mortality of ICU-acquired infections in patients admitted with or without sepsis.
This cluster randomized trial investigated the effects of a quality improvement intervention comprising checklists, goal setting, and clinician follow-up vs routine care on mortality among adults in Brazilian intensive care units.
This cohort study tracked children living in Southern California over 16 years to determine whether improvements in air quality were associated with reductions in bronchitic symptoms.
This randomized clinical trial assesses the effectiveness of dexmedetomidine when added to standard care in patients with agitated delirium receiving mechanical ventilation.
This survey study examines how well physicians understand the US Food and Drug Administration’s (FDA’s) statutory definition of a “breakthrough” therapy, and whether the term breakthrough affects their perceptions of a drug’s efficacy.
This Viewpoint uses the Nightscout Project, a patient-developed mobile technology system, to discuss safety, legal, and regulatory challenges to the broader use of mobile health technology.
This Viewpoint discusses the need for examination of long-term patterns across a broad range of risk factors in predicting patients’ lifetime risk of atherosclerotic cardiovascular disease.
This Viewpoint discusses the Global Health Risk Framework Commission’s strategy to safeguard human and economic security from pandemic threats.
This Rational Clinical Examination systematic review summarizes the diagnostic accuracy of physical examination and laboratory findings for diagnosing infectious mononucleosis in adolescent and young adults.
This JAMA Clinical Guidelines Synopsis summarizes the American Academy of Dermatology’s 2014 guideline on management of atopic dermatitis.
This Medical Letter review summarizes the safety of testosterone therapy for the improvement of sexual function, physical function, and vitality in older men with low serum testosterone levels and symptoms suggesting hypoandrogenism.
This Medical News & Perspectives article discusses the recommendations on added sugar intake as part of the recent Dietary Guidelines released by the HHS and USDA.
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