This View Point presents the practice of concurrent surgeries, calls for 3 steps to regulate the practice, and advocates more direct communication with patients about the practice.
This Viewpoint attempts to explain flaws in bills from both houses of Congress to update the Toxic Substances Control Act for the first time in 40 years.
This Viewpoint discusses new laws that improve women’s access to contraceptives and the ways that critics say the laws fall short.
This Editorial discusses the use of PD-1 blockade in treating patients with metastatic melanoma in the KEYNOTE-1 trial.
This 2-stage randomized clinical trial compared lipid-lowering efficacy of 2 nonstatin therapies, ezetimibe and evolocumab, among patients with uncontrolled low-density lipoprotein cholesterol levels and intolerance to 2 or more statins.
This randomized trial evaluates the efficacy and safety of losmapimod vs placebo on cardiovascular outcomes in patients hospitalized with an acute myocardial infarction (MI).
This study pools patient cohorts from randomized and nonrandomized studies to investigate associations between pembrolizumab therapy and tumor response among patients with advanced melanoma with and without prior ipilimumab therapy.
This phase 1 randomized clinical trial investigated the safety and tolerability of 2 vaccines against Ebola virus: an adenovirus type 26 vector vaccine encoding Ebola glycoprotein (Ad26.ZEBOV) and a modified vaccinia Ankara vector vaccine encoding glycoproteins from Ebola virus, Sudan virus, Marburg virus, and Tai Forest virus nucleoprotein (MVA-BN-Filo).
This guideline from the Centers for Disease Control and Prevention makes 12 recommendations to improve communication about opioids for chronic pain, to improve the safety and effectiveness of pain treatment, and to reduce risks associated with long-term opioid therapy.
This JAMA Guide to Statistics and Methods discusses how to interpret the results of clinical trials that are stopped early based on formal, prespecified stopping rules.
A 25-year-old woman with hypothyroidism presented with recent fatigue and weight loss. A peripheral blood smear and bone marrow biopsy showed megaloblastic changes; laboratory analysis showed pancytopenia and elevated levels of lactate dehydrogenase and vitamin B12. What would you do next?
This study examines the frequency of opioid prescriptions filled within 7 days of extraction among Medicaid patients.
This study assesses trends in the amount of hydrocodone/acetaminophen and oxycodone/acetaminophen prescribed for postoperative pain management.
This Medical News & Perspectives article explores how the study of naturally occurring cancers in pet dogs is helping advance cancer research for humans.
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