This randomized trial compares the effects of induction gemcitabine with vs without erlotinib in patients with locally advanced pancreatic cancer and, among those responsive to treatment, compares the effects of chemotherapy with vs without radiation.
This randomized clinical trial compares the effects of a web-based guided self-help intervention vs enhanced usual care for prevention of major depressive disorder among adults with subthreshold depression.
This pharmacoepidemiology study estimates the rate of outpatient, oral antibiotic prescribing by age and diagnosis in the United States and the estimated portion of antibiotic use that may be inappropriate in adults and children.
This study investigated whether an employer-sponsored health care price transparency tool was associated with lower employee outpatient spending.
This population epidemiology study uses regional claims data from Germany to investigate associations between infections in the first 2 years of life and development of type 1 diabetes.
This Viewpoint discusses the National Patient Safety Foundation’s report Free From Harm: Accelerating Patient Safety Improvement 15 Years After “To Err Is Human” and whether the recommendations achieve total systems safety.
This Viewpoint discusses how policy makers might develop and implement standardized, validated metrics to track the progress of patient safety improvements.
This Viewpoint discusses issues related to the use of “provider” to describe primary care health professionals with varying levels of training and certification and the effects of these issues on quality of care.
This narrative review summarizes types of pancreatic cysts and management strategies for each based on a synthesis of the published literature.
This commentary discusses a survey study published in JAMA Dermatology that investigated whether government organizations in Colorado had occupational sun protection policies.
A 79-year-old man with a history of hypertension and stroke presented to the emergency department unresponsive with an undetectable temperature. Blood pressure was 85/55 mm Hg; pulse oximetry was 100% on ambient air. An ECG revealed sinus bradycardia with Osborn waves and attenuated P waves. What would you do next?
This Medical News & Perspectives article discusses the role of folic acid fortification of cereal grain products in reducing the risk of infant neural tube defects, as well as a push to allow voluntary fortification of corn masa flour.