This randomized clinical trial explores the use of aspirin vs placebo as an early intervention for preventing acute respiratory distress syndrome (ARDS) in at-risk patients presenting to the emergency department.
This retrospective study compared risk of death among Medicaid patients in Tennessee initiating long-acting opioid therapy for chronic noncancer pain with patients taking anticonvulsants or cyclic antidepressants.
This network meta-analysis compares weight loss and adverse events with available drug treatments for obesity, including liraglutide, naltrexone-bupropion, and lorcaserin.
This clinical trial tested whether noninvasive ventilation delivered via helmet reduced intubation rates among intensive care adult patients with acute respiration distress syndrome compared with ventilation delivered via face mask.
This study uses trauma center registry data to describe the severity and mortality of gunshot wounds seen at a Colorado trauma center and its catchment area between 2000 and 2013.
This Viewpoint discusses ways to improve the physical examination using principles of measurement science and technology development.
This Viewpoint describes the efforts of social enterpreneurs, individuals and organizations who develop self-sustaining business models to deliver cost-effective health care and social services to poor and underserved communities around the world.
This Viewpoint discusses how prepared the United States is to handle a Zika virus outbreak and highlights areas of concern in the current health system.
This Viewpoint discusses the Medicare Access and CHIP Reauthorization Act and the key features of the law and the opportunities it presents to shape the future of payment and medical practice.
Notice of Retraction
This narrative review summarizes current evidence about the diagnosis and treatment of polymyalgia rheumatica and giant cell arteritis.
This commentary discusses a meta-analysis published in JAMA Internal Medicine that evaluated the efficacy of opioids as treatment for back pain.
This Medical Letter review summarizes antibiotic regimens to treat the dermatological, neurological, cardiac, and rheumatological manifestations of Lyme disease.
This Medical News feature examines mindfulness meditation as a nonpharmacologic approach to managing chronic pain.