This randomized clinical trial evaluates the effects of intensive (<120 mm Hg) systolic blood pressure targets compared with standard (<140 mm Hg) systolic blood pressure targets in patients aged 75 years or older.
This randomized clinical trial compares the effects of escitalopram with placebo on death and hospitalization among patients with chronic systolic heart failure and depression.
This randomized clinical trial compares the effects of physical rehabilitation vs usual care on length of stay of ICU patients with acute respiratory failure.
This randomized clinical trial compares the effect of a primary care–based management intervention vs usual care on mental health–related quality of life among patients surviving sepsis in the critical care setting.
This study describes the proportion of trials registered at ClinicalTrials.gov and sponsored by 4 pharmaceutical companies included on the Clinical Study Data Request website, where researchers can request access to anonymized patient-level data.
This Viewpoint describes the rapid spread of use of high-intensity focused ultrasound ablation as a treatment for prostate cancer and calls for establishment of a registry to better assess the efficacy and safety of this approach.
This Viewpoint discusses the yellow fever epidemic in Angola as well as in China, the Democratic Republic of Congo, and Kenya due to cases arising from infected travelers from Angola.
This Viepoint describes collaborations between health care organizations and public health departments or community agencies described in articles submitted to the National Academy of Medicine for their Collaborative on Bridging Public Health, Health Care, and Community.
This Viewpoint discusses alternative payment models that reward value and quality, focusing on the Centers for Medicare & Medicaid Services’ Comprehensive Primary Care Plus model for advanced primary care medical homes.
This Narrative Review summarizes published evidence about the epidemiology, etiology, diagnosis, and management of persistent diarrhea.
This commentary discusses a survey study published in JAMA Dermatology that described the changes in the prices of commonly prescribed dermatologic drugs at national chain pharmacies over a 6-year period.
A 65-year-old man with hypertension had trace blood on a routinely performed dipstick urinalysis.What would you do next?
This Medical News story discusses research that identifies a positive association between oral microbiome dysbiosis and pancreatic cancer.
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