This randomized trial compares the effects of adding dupilumab, an IL-4 and IL-13 signalling inhibitor, to mometasone furoate nasal spray vs mometasone alone in adults with chronic sinusitis and nasal polyposis refractory to intranasal corticosteroids.
This randomized controlled trial assesses whether acetazolamide reduces mechanical ventilation duration among critically ill patients with chronic obstructive pulmonary disease and metabolic alkalosis.
This cohort study describes correlations and associations between premortem seafood intake, postmortem brain mercury levels, and postmortem Alzheimer disease neuropathology in older adults.
This cohort study uses paired inspiratory-expiratory computed tomography images to determine the prevalence and clinical significance of expiratory central airway collapse among current and former smokers.
This study uses employer-sponsored private insurance claims data to determine the proportion of colonoscopies for colon cancer screening and polyp surveillance that were preceded by office visits and the associated insurance payments for those visits between 2010 and 2013.
This Viewpoint summarizes the updated recommendations of the US Department of Health and Human Services’ recently released 2015-2020 Dietary Guidelines for Americans.
This Viewpoint discusses opportunities and challenges facing academic health systems as they move beyond providing individual-patient care and population-specific management to providing health improvement at the population level.
This Viewpoint maintains that the US Food and Drug Administration (FDA) should have a more active role in the approval and marketing of off-patent pharmaceutical products.
This Editorial expresses the potential benefits of fatty fish consumption in helping protect older adults from developing Alzheimer disease and other forms of dementia.
This commentary discusses a study published in JAMA Otolaryngology–Head & Neck Surgery that evaluated transcranial magnetic stimulation for the treatment of chronic tinnitus.
A 46-year-old woman presented with well-demarcated erythematous scaly plaques, with central clearing, on her chest, back, flanks, and groin. She reported that the eruption worsens with warmer weather but reported no other pain or rash. What would you do next?
This Medical Letter review summarizes what is known about the safety of use of drugs past their expiration date in the United States.
This Medical News & Perspectives article explores reasons for the decrease in the infant mortality rate in the United States, as well as reasons why it is still higher than that of other industrialized countries.
Create a personal account or sign in to: