This Viewpoint discusses prospects for developing new and effective therapeutic strategies for the treatment of critically ill patients.
This Viewpoint discusses the importance of preserving cerebral function in critical care settings and the challenges of providing care that promotes recovery of brain function and improved functional outcomes.
This Viewpoint proposes improvements in the organizational delivery of critical care services and in quality improvement strategies to ensure high-value care even in settings with intensivist shortages.
This Viewpoint discusses the challenges of providing intensive care in settings and countries with limited resources.
This cohort study uses health system and research cohort data to compare the ability of existing vs new clinical criteria for sepsis to identify intensive care unit patients with suspected infection at higher mortality risk.
This article describes the results of a meta-analysis of criteria used to identify adults with septic shock and the processes by which a critical care task force used the results to revise current septic shock definitions.
This cohort study reports the incidence of and outcomes for patients with acute respiratory distress syndrome treated in intensive care units in 50 countries in 2014.
This article presents updated definitions of and clinical criteria for diagnosing sepsis and septic shock based on recommendations from an expert task force.
This commentary discusses a cohort study published in JAMA Surgery that investigated the role of shared decision making in nonsurgical vs surgical management of uncomplicated acute appendicitis in children.
This Clinical Evidence Synopsis summarizes a Cochrane review on the efficacy of topical nonsteroidal anti-inflammatory drugs to treat musculoskeletal conditions, such as sprains, strains, and contusions.
This case-control study explores the association between circulating histones and thrombocytopenia in patients in the intensive care unit.
This Medical News & Perspectives article discusses new sepsis diagnostic guidelines developed by a joint task force of the Society of Critical Care Medicine and European Society of Intensive Care Medicine.
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