This randomized clinical trial compares the effects of short-term high-dose perioperative atorvastatin vs placebo on acute kidney injury following cardiac surgery.
This cohort study examines the association between red blood cell transfusion, severe neonatal anemia, and necrotizing enterocolitis among very low-birth-weight infants during the first 90 days of life.
This noninferiority trial compares the effects of a fixed ratio of insulin degludec/liraglutide vs up-titration of insulin glargine on glycated hemoglobin levels among patients with uncontrolled type 2 diabetes treated with glargine and metformin.
This study uses US census and national survey data to investigate the proportion of married physicians who have highly educated spouses, and the odds of the couple living and working in rural underserved areas.
This Recommendation Statement from the US Preventive Services Task Force concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for impaired visual acuity among adults 65 years or older who do not present to their primary care clinician with vision problems.
This Viewpoint discusses the use of loyalty programs within accountable care organizations as a means of achieving patient-centric care and enhancing the health system business model.
This Viewpoint discusses Zika virus infection and health system preparedness and urges the World Health Organization to proactively respond to the growing global threat of infection.
This Viewpoint urges greater involvement of primary care physicians in screening patients for risky sexual behaviors and prescribing preexposure prophylactic antiviral medication to those at risk of HIV infection.
This Viewpoint describes steps taken by Oregon to change its Medicaid program to improve health care access and population health and slow increases in spending.
This systematic review to support the 2016 update of the US Preventive Services Task Force Recommendation Statement on screening for impaired visual acuity in older adults summarizes trial evidence about screening and treatment and evidence about the diagnostic accuracy of screening instruments.
On day 3 after birth, a full-term neonate developed a pustular rash over the face and trunk that progressed to a “flea-bitten” pattern on the limbs. Wright staining showed eosinophils, Tzanck smear and bacterial and fungal cultures were negative, and WBC count and ESR were normal. What would you do next?
A 25-year-old man with interest in future fertility presented to the urology clinic with concerns of low energy but no symptoms of low libido, erectile dysfunction, or ejaculatory dysfunction (his FSH level was in the high-normal reference range, luteinizing hormone was elevated, and he had bilateral testicular atrophy and azoospermia). How do you interpret the test results?
In this Medical News & Perspectives piece, Robert O Bonow, MD, the editor-in-chief of JAMA Cardiology, discusses his editorial vision for the new journal.
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