This randomized clinical trial compares the effects of a technology-enhanced vs a standard behavioral weight loss intervention on achieving weight loss over 24 months among adults.
This pragmatic randomized trial compares the effects of a second anti–tumor necrosis factor (TNF) drug vs non–TNF-targeted biologic therapy among patients with rheumatoid arthritis for whom a first anti-TNF drug had failed.
This meta-analysis summarizes evidence about associations between timing of allergenic food introduction during infancy and risk of allergic or autoimmune disease.
This retrospective cross-sectional analysis of pharmacy data indicates that most buprenorphine prescribers’ patient censuses are considerably below current limits.
In this Special Communication, Anthony Fauci and colleagues review ecological factors contributing to, mechanisms of, and novel strategies to manage antimicrobial resistance.
This Viewpoint proposes that institutional review boards play a larger role in ensuring timely public reporting of clinical trial results, with the goals of promoting medical innovation, reducing publication bias, and maximizing the value of clinical trials.
This Viewpoint proposes that reminders about professional standards might prevent counterproductive responses of physicians to report card comparisons intended to improve health care quality and reduce waste.
This Viewpoint discusses creation of a US evaluation system for health technology that could quickly identify problematic devices, accurately and transparently characterize and disseminate information about device performance in clinical practice, and efficiently generate data to support premarket clearance or approval of new devices and new uses of currently marketed devices.
This Guide to Statistics article compares pragmatic randomized controlled trials, which focus on important challenges that patients, physicians, and policy makers face in day-to-day life with explanatory trials that seek to test a hypothesis.
This JAMA Performance Improvement uses the case of a patient given the wrong catheter to discuss appropriate clinician and health system responses to procedure errors.
This Medical News feature discusses the progress and challenges in HIV/AIDS treatement and research highlighted by the 2016 International AIDS conference in Durban, South Africa.
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