This open-label trial compares onabotulinumtoxinA with sacral neuromodulation to treat older US adult women with refractory urgency urinary incontinence.
This cohort study uses Get With the Guidelines–Resuscitation registry data to evaluate the association between use of therapeutic hypothermia and survival after in-hospital cardiac arrest.
This meta-analysis of genetic association studies summarizes associations between molecular targets of lipid-lowering therapy and risk of type 2 diabetes and coronary artery disease.
This study describes the safety of a hybrid closed-loop insulin delivery system among patients with type 1 diabetes.
This Viewpoint from the National Institutes of Health describes a new set of guidelines for the conduct and registration of clinical trials in the United States.
In this Viewpoint, John Ioannidis and colleagues review how rarely gene therapy and genomic medicine have led to breakthroughs for patients and call on the NIH to defund preclinical research that fails to deliver on its initial promise.
This Viewpoint discusses differing opinions on whether precision medicine can help improve US population health and if so, potential approaches to implementing a coordinated and effective effort between the medical and public health communities.
This Viewpoint discusses difficulties of using testosterone and other physiologic testing to confirm sex and event eligibility in phenotypically female athletes competing in the 2016 Summer Olympic Games in Brazil.
This Viewpoint describes efforts to revise language and policies in ways that frame addiction as a treatable chronic brain disorder rather than as a moral failing of people who use addictive substances.
This systematic review summarizes current evidence on effective treatments for nausea and vomiting in pregnancy and hyperemesis gravidarum.
This JAMA Clinical Guidelines Synopsis article summarizes the American Academy of Dermatology guidelines on the treatment of acne.
This Medical Letter review summarizes appropriate alternative antibiotic treatment of sinusitis, bronchitis, and uncomplicated urinary tract infections in the wake of US Food and Drug Administration labeling changes warning of the risks of fluoroquinolones.
This Medical News story features a Q&A with physician-scientist and entrepreneur Patrick Soon-Shiong, MD, discussing the ‘cancer moonshot’ and promising approaches in cancer immunotherapy.
This The Arts and Medicine article describes the changing contents of physicians’ libraries.
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