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August 2019 - July 1883




October 4, 2016, Vol 316, No. 13, Pages 1329-1420

In This Issue of JAMA


Abstract Full Text
free access has audio
JAMA. 2016;316(13):1329-1331. doi:10.1001/jama.2015.14510
Original Investigation

OnabotulinumtoxinA vs Sacral Neuromodulation on Refractory Urgency Urinary Incontinence in Women: A Randomized Clinical Trial

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JAMA. 2016;316(13):1366-1374. doi:10.1001/jama.2016.14617

This open-label trial compares onabotulinumtoxinA with sacral neuromodulation to treat older US adult women with refractory urgency urinary incontinence.

Caring for the Critically Ill Patient

Association Between Therapeutic Hypothermia and Survival After In-Hospital Cardiac Arrest

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JAMA. 2016;316(13):1375-1382. doi:10.1001/jama.2016.14380

This cohort study uses Get With the Guidelines–Resuscitation registry data to evaluate the association between use of therapeutic hypothermia and survival after in-hospital cardiac arrest.

Association Between Low-Density Lipoprotein Cholesterol–Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis

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JAMA. 2016;316(13):1383-1391. doi:10.1001/jama.2016.14568

This meta-analysis of genetic association studies summarizes associations between molecular targets of lipid-lowering therapy and risk of type 2 diabetes and coronary artery disease.

Research Letter

Safety of a Hybrid Closed-Loop Insulin Delivery System in Patients With Type 1 Diabetes

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JAMA. 2016;316(13):1407-1408. doi:10.1001/jama.2016.11708

This study describes the safety of a hybrid closed-loop insulin delivery system among patients with type 1 diabetes.


Toward a New Era of Trust and Transparency in Clinical Trials

Abstract Full Text
JAMA. 2016;316(13):1353-1354. doi:10.1001/jama.2016.14668

This Viewpoint from the National Institutes of Health describes a new set of guidelines for the conduct and registration of clinical trials in the United States.

What Happens When Underperforming Big Ideas in Research Become Entrenched?

Abstract Full Text
JAMA. 2016;316(13):1355-1356. doi:10.1001/jama.2016.11076

In this Viewpoint, John Ioannidis and colleagues review how rarely gene therapy and genomic medicine have led to breakthroughs for patients and call on the NIH to defund preclinical research that fails to deliver on its initial promise.

Will Precision Medicine Improve Population Health?

Abstract Full Text
JAMA. 2016;316(13):1357-1358. doi:10.1001/jama.2016.12260

This Viewpoint discusses differing opinions on whether precision medicine can help improve US population health and if so, potential approaches to implementing a coordinated and effective effort between the medical and public health communities.

The Olympic Games and Athletic Sex Assignment

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JAMA. 2016;316(13):1359-1360. doi:10.1001/jama.2016.11850

This Viewpoint discusses difficulties of using testosterone and other physiologic testing to confirm sex and event eligibility in phenotypically female athletes competing in the 2016 Summer Olympic Games in Brazil.

Changing the Language of Addiction

Abstract Full Text
JAMA. 2016;316(13):1361-1362. doi:10.1001/jama.2016.11874

This Viewpoint describes efforts to revise language and policies in ways that frame addiction as a treatable chronic brain disorder rather than as a moral failing of people who use addictive substances.

A Piece of My Mind

The Quick Physical Exam

Abstract Full Text
JAMA. 2016;316(13):1363-1364. doi:10.1001/jama.2016.8182

Introducing The Arts and Medicine: JAMA Turns Another Page

Abstract Full Text
JAMA. 2016;316(13):1365. doi:10.1001/jama.2016.14822

Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review

Abstract Full Text
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JAMA. 2016;316(13):1392-1401. doi:10.1001/jama.2016.14337

This systematic review summarizes current evidence on effective treatments for nausea and vomiting in pregnancy and hyperemesis gravidarum.

JAMA Clinical Guidelines Synopsis

Management of Acne Vulgaris

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JAMA. 2016;316(13):1402-1403. doi:10.1001/jama.2016.11842

This JAMA Clinical Guidelines Synopsis article summarizes the American Academy of Dermatology guidelines on the treatment of acne.

From The Medical Letter on Drugs and Therapeutics

Alternatives to Fluoroquinolones

Abstract Full Text
JAMA. 2016;316(13):1404-1405. doi:10.1001/jama.2016.8383

This Medical Letter review summarizes appropriate alternative antibiotic treatment of sinusitis, bronchitis, and uncomplicated urinary tract infections in the wake of US Food and Drug Administration labeling changes warning of the risks of fluoroquinolones.

Medical News & Perspectives

Surgeon, Scientist, and Entrepreneur: One Man’s Fight Against Cancer

Abstract Full Text
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JAMA. 2016;316(13):1345-1347. doi:10.1001/jama.2016.9304

This Medical News story features a Q&A with physician-scientist and entrepreneur Patrick Soon-Shiong, MD, discussing the ‘cancer moonshot’ and promising approaches in cancer immunotherapy.

News From the Food and Drug Administration

Avoiding Open-Heart Surgery

Abstract Full Text
JAMA. 2016;316(13):1350. doi:10.1001/jama.2016.13788

Evaluating Patients for Concussion

Abstract Full Text
JAMA. 2016;316(13):1350. doi:10.1001/jama.2016.13803

Programmable Syringe Pump Alert

Abstract Full Text
JAMA. 2016;316(13):1350. doi:10.1001/jama.2016.13805
The JAMA Forum

Why Are Private Health Insurers Losing Money on Obamacare?

Abstract Full Text
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JAMA. 2016;316(13):1347-1348. doi:10.1001/jama.2016.13743
Lab Reports

Imaging Epigenetics in the Human Brain

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JAMA. 2016;316(13):1349. doi:10.1001/jama.2016.13667

How Oral Microbes Exacerbate Colorectal Cancer

Abstract Full Text
JAMA. 2016;316(13):1349. doi:10.1001/jama.2016.14157

Reservoir of Genetic Data Related to Cardiovascular Disease

Abstract Full Text
JAMA. 2016;316(13):1349. doi:10.1001/jama.2016.14159
The Arts and Medicine

What’s in Your Library?“The Leaven of the Humanities”

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JAMA. 2016;316(13):1340-1341. doi:10.1001/jama.2016.9536

This The Arts and Medicine article describes the changing contents of physicians’ libraries.

Poetry and Medicine

Post-Op Essay

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JAMA. 2016;316(13):1413. doi:10.1001/jama.2016.7369
JAMA Revisited

The Lower Animals and Human Disease

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JAMA. 2016;316(13):1414. doi:10.1001/jama.2015.17104
JAMA Patient Page

Treatments for Nausea and Vomiting During Pregnancy

Abstract Full Text
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JAMA. 2016;316(13):1420. doi:10.1001/jama.2016.14737
Comment & Response

Radiation Therapy Deviations in Trial of Locally Advanced Pancreatic Cancer

Abstract Full Text
JAMA. 2016;316(13):1409. doi:10.1001/jama.2016.9778

Radiation Therapy Deviations in Trial of Locally Advanced Pancreatic Cancer—Reply

Abstract Full Text
JAMA. 2016;316(13):1409. doi:10.1001/jama.2016.9781

Improving the Physical Examination

Abstract Full Text
JAMA. 2016;316(13):1410. doi:10.1001/jama.2016.12233

Improving the Physical Examination—Reply

Abstract Full Text
JAMA. 2016;316(13):1410-1411. doi:10.1001/jama.2016.12236

Primary Care “Provider” and Professional Identity

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JAMA. 2016;316(13):1411. doi:10.1001/jama.2016.9772

Primary Care “Provider” and Professional Identity

Abstract Full Text
JAMA. 2016;316(13):1411. doi:10.1001/jama.2016.9775

Primary Care “Provider” and Professional Identity—Reply

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JAMA. 2016;316(13):1412. doi:10.1001/jama.2016.9784

Error in Table Row Alignment and No. of Participants

Abstract Full Text
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JAMA. 2016;316(13):1412. doi:10.1001/jama.2016.13819
JAMA Masthead


Abstract Full Text
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JAMA. 2016;316(13):1333-1334. doi:10.1001/jama.2015.14511