This randomized clinical trial compares the effects of a below-knee cast vs surgery on ankle symptoms and functional outcomes at 6 months among older adults with an unstable ankle fracture.
This pharmacoepidemiology study uses NHANES data to report trends in dietary supplement use among US adults (between 1999 and 2012).
This study compares before-after changes in Medicaid revenues and uncompensated care at hospitals in states with vs without expansion of Medicaid.
This case series describes the diagnostic yield of whole-exome sequencing (molecular autopsy) performed postmortem on patients younger than 45 years who died unexpectedly.
This Viewpoint discusses whether hospital-affiliated outpatient birth centers might improve birth outcomes and patient experience and safely reduce annual US health care spending for women at low risk of obstetric and perinatal complications.
In this Viewpoint, CDC Director Thomas Frieden and colleagues provide a mid-2016 update on Zika virus infection, including advances in understanding the epidemiology, clinical manifestations, diagnosis, prevention, and public health control of the infection.
This Viewpoint reviews the events leading to the UK junior doctors’ strike and discusses the potential long-term harm to medicine in the United Kingdom if a contract is not negotiated.
This Viewpoint discusses the value judgments that are always incorporated into payers’ and health systems’ assessments of the clinical- and cost-effectiveness of interventions and into their discussions whether to adopt them.
This Clinical Evidence Synopsis summarizes a Cochrane review of clinical trials comparing the effects of probiotics vs placebo, no treatment, or active treatment on antibiotic-associated diarrhea in children given antibiotics.
This JAMA Clinical Guidelines Synopsis summarizes the Society for Vascular Surgery’s 2015 guideline on screening, evaluation, and treatment of peripheral arterial disease.
A 47-year-old man with severe Crohn disease developed nystagmus and lower extremity hyperalgesia after elective colectomy and follow-up surgery for an enterocutaneous fistula. MRI of the brain showed hyperintensity in both medial thalami. What would you do next?
This Medical News article discusses a push to reduce pregnancy and childhood exposures to neurodevelopmental toxins.
Review of The Effect, a play that features characters in a clinical trial.
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