This randomized clinical trial compares the effects of hydrocortisone vs placebo on development of septic shock among intensive care patients with severe sepsis who were not in septic shock.
This cohort study using data from the Get With The Guidelines–Resuscitation quality improvement registry to investigate the association between intubation during in-hospital pediatric cardiac arrest and survival to hospital discharge.
This cohort study evaluates whether prescription of psychotropic medications was associated with rates of violent reoffending in Swedish adults released from prison.
This phase 1 trial evaluates safety and wound outcomes after transplant of genetically corrected autologous epidermal grafts onto wounds of patients with recessive dystrophic epidermolysis bullosa.
This cohort study uses Vaccine Safety Datalink data to examine associations between maternal Tdap vaccination and structural birth defects in offspring.
This Viewpoint proposes 8 factors to consider before adopting a peer-comparison model designed to guide physicians toward improving the value of care.
This Viewpoint discusses hospital rating systems and ways to improve them to drive quality improvement efforts and provide patients with relevant, accessible composite information.
This Viewpoint discusses challenge of determining appropriate therapies for chronic pain as federal guidelines emphasize efforts to decrease opioid abuse while some US states initiate legalized medical use of cannabis.
This Viewpoint calls for improved surveillance of the use and of health effects of marijuana in the wake of evolving state policies that increase legal access to the drug.
This JAMA Guide to Statistics and Methods reviews the use of methods to control for confounding by indication in clinical research.
This Medical Letter review summarizes what is known about Probuphine, a newly approved subdermal implant form of buprenorphine that provides continuous low levels of drug to prevent opioid use in patients with dependence to opioids.
This medical news feature discusses the recent row between Nobel laureates and Greepeace over genetically modified foods.
Where medicine leaves off, poetry provides companionship in the presence of loss.
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