This randomized clinical trial compares the effects of sedation with vs without dexmedetomidine on mortality and ventilator-free days in patients with sepsis.
This secondary analysis of outcomes from the PREMILOC (Early Low-Dose Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia in Extremely Preterm Infants) trial compares neurodevelopmental impairment in neonates given hydrocortisone vs placebo.
This study uses SEER database data to compare thyroid cancer incidence and mortality rates in the United States by cancer type and stage between 1974 and 2013.
This randomized clinical trial assesses whether moderate-intensity exercise training, compared with usual activity, improves exercise capacity in adults with hypertrophic cardiomyopathy.
This cohort study compares cortical volume change over 18 months among adults 80 years and older with memory at least as good as middle-aged adults (SuperAgers) vs cognitively average elderly peers.
This Viewpoint proposes steps that policy makers and health systems can take to make high-quality shared decision making more routine in clinical practice.
This Viewpoint proposes newly conceivable federal policy options under a Republican president and Congress that may offer a more bipartisan and comprehensive approach to medical liability reform.
With increasing consolidation of US physician practices and hospitals into health care systems, this Viewpoint discusses the negative effects on quality of patient care and health care costs, and it proposes potential solutions.
This narrative review summarizes screening, diagnosis, and treatment options for patients with obsessive-compulsive disorder.
This commentary discusses a case series of infants with congenital Zika virus infection published in JAMA Neurology that described developmental abnormalities more severe than had been previously reported.
A 35-year- old man had 4 days of fever, confusion, and jaundice after travel to Sierra Leone, where he did not take malaria prophylaxis or use insect repellent. His blood smear showed Plasmodium falciparum ring forms. What would you do next?
This Medical News feature discusses the role of circadian clock in regulating metabolism.
This Arts and Medicine essay reviews David Frances’s book, How to Survive a Plague, an extensive account of the AIDS activists in the 1980s and 1990s who effectively mobilized to provide medical treatment and support for those suffering from the disease.