This randomized controlled trial compared the effects of a single dose of dexamethasone vs placebo on sore throat symptoms among adults with acute sore throat not requiring immediate antibiotics.
This cohort study uses health administrative data from Ontario, Canada, to compare development of autism spectrum disorder in children exposed vs not exposed to serotonergic antidepressants in utero.
This cohort study of 1 580 629 offspring born to mothers exposed vs nonexposed to first-trimester antidepressant use compared outcome rates of preterm birth, small for gestational age, autism, and attention-deficit/hyperactivity disorder.
This study uses NHANES data to compare the numbers of US adults eligible for primary prevention statin treatment under USPSTF vs ACC/AHA guideline criteria.
This study compares the diagnostic accuracy of a 2-transcript vs 66-transcript host RNA disease risk score for distinguishing bacterial from viral infection in febrile infants ≤60 days old presenting to the emergency department.
This study compares trends in Medicare payment adjustments to safety-net vs non–safety-net hospitals under Hospital Readmission Reduction Program (HRRP) and Value-Based Purchasing programs, intended to incentivize higher-quality health care.
In this Viewpoint, Hodge and Gostin summarize the most important 2017 updates to the US Federal Policy for the Protection of Human Subjects.
This Viewpoint discusses the evolution of the Hyde Amendment, which in 1976 prohibited use of medical funds to pay for abortion except when the mother’s life is endangered, and efforts since then to nullify the amendment or codify it as a federal statute.
This Viewpoint discusses the rationale for partnerships between law enforcement and public health agencies and suggests strategies to form such partnerships to prevent and respond to violence.
This Viewpoint proposes that standards for interpretation of genetic variants be expanded to include protective as well as pathogenic variants and stresses the importance of considering protective variants for assessing disease risk and guiding clinical decision making.
This Viewpoint discusses ways to improve adherence to the Dietary Approaches to Stop Hypertension (DASH) diet, which comprises foods rich in protein and fiber, limits foods high in saturated fat and sugar, and was shown in 1997 to lower blood pressure in patients with hypertension and prehypertension.
This commentary discusses a study published in JAMA Pediatrics that reported an association between use of antidepressants, specifically selective serotonin reuptake inhibitors (SSRIs) during the second and/or third trimesters and autism spectrum disorder in children.
This JAMA Professionalism article uses the example of a 70-year-old physician who has concerns about his performance to discuss physician aging and its relationship to competency in clinical medical practice.
This JAMA Clinical Guidelines Synopsis summarizes the 2016 Maastricht V/Florence Consensus Report on management of Helicobacter pylori infection.
A woman presented with 6 months of yellowing skin on her palms and soles 6 months after beginning to take beta carotene supplements. She had no scleral icterus; liver enzyme and bilirubin values were normal, as were results of thyroid function tests. What would you do next?
This Medical News article discusses how physicians can become educated and involved in strategies to combat climate-related health challenges.
This Arts and Medicine essay discusses the parallels between the encounter of truth and beauty in art and the clinical relationship between physicians and patients.
Notice of Retraction and Replacement: Oostdijk et al. Effects of Decontamination of the Oropharynx and Intestinal Tract on Antibiotic Resistance in ICUs: A Randomized Clinical Trial. JAMA. 2014;312(14):1429-1437.