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January 2022 - July 1883




June 6, 2017, Vol 317, No. 21, Pages 2145-2248

In This Issue of JAMA


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JAMA. 2017;317(21):2145-2147. doi:10.1001/jama.2016.13152
Original Investigation

Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation: A Randomized Clinical Trial

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JAMA. 2017;317(21):2177-2186. doi:10.1001/jama.2017.4451

This randomized clinical trial compares the effects of home oxygen therapy with vs without home noninvasive ventilation (NIV) on time to readmission or death in patients with persistent hypercapnia after an acute chronic obstructive pulmonary disease (COPD) exacerbation.

Caring for the Critically Ill Patient

Discriminative Accuracy of Physician and Nurse Predictions for Survival and Functional Outcomes 6 Months After an ICU Admission

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JAMA. 2017;317(21):2187-2195. doi:10.1001/jama.2017.4078

This study assesses the 6-month discriminative accuracy of patient mortality and functional outcome predictions made by intensive care unit (ICU) physicians and nurses at the time of ICU admission.

Association of Implementation of a Universal Testing and Treatment Intervention With HIV Diagnosis, Receipt of Antiretroviral Therapy, and Viral Suppression in East Africa

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JAMA. 2017;317(21):2196-2206. doi:10.1001/jama.2017.5705

This analysis examines intervention communities in rural Uganda and Kenya in an ongoing cluster randomized trial to assess the change in the proportions of HIV-positive residents diagnosed with HIV, treated with ART, and achieving HIV viral suppression.

Association of Gestational Weight Gain With Maternal and Infant Outcomes: A Systematic Review and Meta-analysis

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JAMA. 2017;317(21):2207-2225. doi:10.1001/jama.2017.3635

This meta-analysis evaluates associations between gestational weight gain above or below the Institute of Medicine guidelines and maternal and infant outcomes including size for gestational age, preterm birth, cesarean delivery, and gestational diabetes mellitus.

Research Letter

Trends in Use of the US Medicare Annual Wellness Visit, 2011-2014

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JAMA. 2017;317(21):2233-2235. doi:10.1001/jama.2017.4342

This study uses Medicare claims data to describe the use of annual wellness visits among Medicare beneficiaries in the United States from 2011 through 2014.

Distribution of Physicians With H-1B Visas By State and Sponsoring Employer

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JAMA. 2017;317(21):2235-2237. doi:10.1001/jama.2017.4877

This study describes the number of H-1B visa physician applications and active care H-1B visa applications physicians by state and employer in 2016.


Breaking the Rules for Better Care

Abstract Full Text
JAMA. 2017;317(21):2161-2162. doi:10.1001/jama.2017.4703

This Viewpoint summarizes rules in health care organizations that their own leaders identified as ones that contribute little or no value to care, impede the work of clinicians, frustrate patients and families, and waste time and resources.

Obstacles to the Adoption of Biosimilars for Chronic Diseases

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JAMA. 2017;317(21):2163-2164. doi:10.1001/jama.2017.5202

This Viewpoint explores why biosimilars for chronic diseases, the largest category of biological therapies, are unlikely to yield cost savings.

A Piece of My Mind

It’s a Beautiful Thing

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JAMA. 2017;317(21):2165-2166. doi:10.1001/jama.2017.3102

Home Noninvasive Ventilation to Reduce Readmissions for Chronic Obstructive Pulmonary Disease

Abstract Full Text
JAMA. 2017;317(21):2167-2169. doi:10.1001/jama.2017.5226

Making Recommendations for Limiting Care in the ICU Based on Sound Prognosis

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JAMA. 2017;317(21):2170-2171. doi:10.1001/jama.2017.4327

Progress Toward Achieving UNAIDS 90-90-90 in Rural Communities in East Africa

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JAMA. 2017;317(21):2172-2174. doi:10.1001/jama.2017.5704

Gestational Weight Gain and Outcomes for Mothers and Infants

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JAMA. 2017;317(21):2175-2176. doi:10.1001/jama.2017.6265
From the JAMA Network

Dietary Intake of Omega-3 Fatty Acids From Fish and Risk of Diabetic Retinopathy

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JAMA. 2017;317(21):2226-2227. doi:10.1001/jama.2017.1926

This commentary discusses an observational study within a randomized clinical trial published in JAMA Ophthalmology that found intake of at least 500 mg/d of dietary long-chain ω-3 polyunsaturated fatty acids (2 weekly servings of oily fish) is associated with a decreased risk of sight-threatening diabetic retinopathy among middle-aged and older individuals with type 2 diabetes.

JAMA Diagnostic Test Interpretation

JAK2 V617F Mutation Testing in Patients Presenting With Hepatic and Portal Vein Thrombosis

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JAMA. 2017;317(21):2228-2229. doi:10.1001/jama.2017.2329

A 27-year-old woman with pain in the right upper quadrant underwent a laparoscopic cholecystectomy. Lab tests were positive for JAK2 V617F, confirming the presence of clonal hematopoiesis. How would you proceed?

From The Medical Letter on Drugs and Therapeutics

Prevention of Migraine

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JAMA. 2017;317(21):2230-2231. doi:10.1001/jama.2017.1680

This Medical Letter review summarizes classes of drugs and other treatments approved by the US Food and Drug Administration for the prevention of migraine.

Medical News & Perspectives

Fogarty International Center, a Linchpin of Global Health Research

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JAMA. 2017;317(21):2152-2153. doi:10.1001/jama.2017.6076

This Medical News article discusses the Fogarty International Center’s contributions to global health research.

News From the Food and Drug Administration

New AML Therapy and Diagnostic

Abstract Full Text
JAMA. 2017;317(21):2157. doi:10.1001/jama.2017.6304

Therapy for Rare Nerve Cell Disease

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JAMA. 2017;317(21):2157. doi:10.1001/jama.2017.6334

Liver Cancer Treatment Approved

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JAMA. 2017;317(21):2157. doi:10.1001/jama.2017.6339
The JAMA Forum

The Fogarty International Center, a National Treasure for Global Health

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JAMA. 2017;317(21):2155-2156. doi:10.1001/jama.2017.6198
Bench to Bedside

Unfolding the Clinical Potential of DNA and Protein Origami

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JAMA. 2017;317(21):2154-2155. doi:10.1001/jama.2017.6288
Poetry and Medicine


Abstract Full Text
JAMA. 2017;317(21):2240. doi:10.1001/jama.2017.0524
JAMA Revisited

The Duty of the Medical Profession in This War

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JAMA. 2017;317(21):2241. doi:10.1001/jama.2017.4823
JAMA Patient Page

Umbilical Hernia

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JAMA. 2017;317(21):2248. doi:10.1001/jama.2017.3982
Comment & Response

Measurement of Hemoglobin A1c in Patients With Sickle Cell Trait

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JAMA. 2017;317(21):2237. doi:10.1001/jama.2017.4643

Measurement of Hemoglobin A1c in Patients With Sickle Cell Trait—Reply

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JAMA. 2017;317(21):2237-2238. doi:10.1001/jama.2017.4646

Adjustment Strategies in Studies of Therapy

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JAMA. 2017;317(21):2238-2239. doi:10.1001/jama.2017.4880

Adjustment Strategies in Studies of Therapy—Reply

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JAMA. 2017;317(21):2238-2239. doi:10.1001/jama.2017.4887

Error in 2 Figures

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JAMA. 2017;317(21):2239. doi:10.1001/jama.2017.5715

Incorrect Data in Abstract, Text, and Figure

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JAMA. 2017;317(21):2239. doi:10.1001/jama.2017.5918
JAMA Masthead


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JAMA. 2017;317(21):2149-2150. doi:10.1001/jama.2016.13153