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November 2017 - July 1883

Decade

Year

Issue

February 14, 2017, Vol 317, No. 6, Pages 555-656

In This Issue of JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2017;317(6):555-557. doi:10.1001/jama.2016.12987
Viewpoint

Hypertension in 2017—What Is the Right Target?

Abstract Full Text
JAMA. 2017;317(6):579-580. doi:10.1001/jama.2017.0105

In this Viewpoint, Chobanian proposes blood pressure goals for treatment of hypertension in light of data from the ACCORD, SPRINT, and HOPE-3 trials, which tested differences in patient outcomes by treatment targets.

New “21st Century Cures” LegislationSpeed and Ease vs Science

Abstract Full Text
JAMA. 2017;317(6):581-582. doi:10.1001/jama.2016.20640

This Viewpoint discusses potential threats to public health that arise from provisions of the 2016 21st Century Cures Act that allow drug manufacturers to use surrogate measures of safety and that encourage the US Food and Drug Administration to emphasize speed over science in the drug approval process.

Language for Actionable Recommendations in Clinical GuidelinesAvoiding Hedging and Equivocation

Abstract Full Text
JAMA. 2017;317(6):583-584. doi:10.1001/jama.2016.20670

This Viewpoint discusses examples of intentional equivocation (hedging) in clinical practice guidelines from professional societies and proposes that less certain or actionable recommendations be removed from guidelines and published in other formats.

A Piece of My Mind

Should the Definition of Health Include a Measure of Tolerance?

Abstract Full Text
JAMA. 2017;317(6):585-586. doi:10.1001/jama.2016.14372
Editorial

Scalp Cooling to Prevent Chemotherapy-Induced AlopeciaThe Time Has Come

Abstract Full Text
JAMA. 2017;317(6):587-588. doi:10.1001/jama.2016.21039

When Will Mendelian Randomization Become Relevant for Clinical Practice and Public Health?

Abstract Full Text
JAMA. 2017;317(6):589-591. doi:10.1001/jama.2016.21189

Sublingual Immunotherapy for Allergic RhinitisIs 2-Year Treatment Sufficient for Long-term Benefit?

Abstract Full Text
JAMA. 2017;317(6):591-593. doi:10.1001/jama.2017.0128

Clinical Practice GuidelinesExpanded Use and Misuse

Abstract Full Text
JAMA. 2017;317(6):594-595. doi:10.1001/jama.2016.19969
Original Investigation

Effect of a Scalp Cooling Device on Alopecia in Women Undergoing Chemotherapy for Breast CancerThe SCALP Randomized Clinical Trial

Abstract Full Text
free access has active quiz has audio
JAMA. 2017;317(6):596-605. doi:10.1001/jama.2016.20939

This randomized clinical trial evaluates whether a scalp cooling device is effective compared with no cooling for reducing alopecia in women with breast cancer undergoing chemotherapy.

Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer

Abstract Full Text
free access
JAMA. 2017;317(6):606-614. doi:10.1001/jama.2016.21038

This cohort study evaluates associations between use of a scalp cooling system and self-assessed hair loss and quality of life among women receiving chemotherapy for early-stage breast cancer at US medical centers.

Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic RhinitisThe GRASS Randomized Clinical Trial

Abstract Full Text
free access has active quiz
JAMA. 2017;317(6):615-625. doi:10.1001/jama.2016.21040

This randomized clinical trial compares the effects of 2 years of sublingual grass pollen immunotherapy vs placebo on nasal symptom scores in adults with moderate to severe seasonal allergic rhinitis.

Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease

Abstract Full Text
free access has active quiz
JAMA. 2017;317(6):626-634. doi:10.1001/jama.2016.21042

This genetic epidemiology study investigates associations between a polygenic risk score for waist-to-hip ratio adjusted for body mass index and risk of type 2 diabetes and coronary heart disease.

JAMA Clinical Guidelines Synopsis

Metabolic Surgery in the Treatment Algorithm for Type 2 DiabetesA Joint Statement by International Diabetes Organizations

Abstract Full Text
JAMA. 2017;317(6):635-636. doi:10.1001/jama.2016.20563

This JAMA Clinical Guidelines Synopsis summarizes a 2016 joint statement by international diabetes organizations recommending metabolic surgery for the treatment of type 2 diabetes in patients with a body mass index of 40 or higher.

JAMA Clinical Challenge

Fever and a Pustular Rash

Abstract Full Text
JAMA. 2017;317(6):637-638. doi:10.1001/jama.2016.18020

A man in his 40s presented with fever, a rash, and progressing acneiform papules and pustules that began 3 days after taking ibuprofen for a mild headache. What would you do next?

From The Medical Letter on Drugs and Therapeutics

Sofosbuvir/Velpatasvir (Epclusa) for Hepatitis C

Abstract Full Text
JAMA. 2017;317(6):639-640. doi:10.1001/jama.2016.12279

This Medical Letter review summarizes background and prescribing information about combination sofosbuvir and velpatasvir, a recently approved oral treatment for all hepatitis C virus genotypes.

Research Letter

Two-Year Follow-up of a Randomized Clinical Trial of Mindfulness-Based Stress Reduction vs Cognitive Behavioral Therapy or Usual Care for Chronic Low Back Pain

Abstract Full Text
free access
JAMA. 2017;317(6):642-644. doi:10.1001/jama.2016.17814

This study describes the 2-year outcomes for participants of a randomized trial of mindfulness-based stress reduction vs cognitive behavioral therapy or usual care for adult participants with chronic low back pain.

Comment & Response

Therapeutic Hypothermia After Cardiac Arrest

Abstract Full Text
JAMA. 2017;317(6):644. doi:10.1001/jama.2016.19826

Therapeutic Hypothermia After Cardiac Arrest

Abstract Full Text
JAMA. 2017;317(6):644. doi:10.1001/jama.2016.19829

Therapeutic Hypothermia After Cardiac Arrest—Reply

Abstract Full Text
JAMA. 2017;317(6):645. doi:10.1001/jama.2016.19832

Birth Center Model of Care

Abstract Full Text
JAMA. 2017;317(6):645-646. doi:10.1001/jama.2016.20479

Birth Center Model of Care

Abstract Full Text
JAMA. 2017;317(6):646. doi:10.1001/jama.2016.20482

Oxygen Supplementation Among Patients in the Intensive Care Unit

Abstract Full Text
JAMA. 2017;317(6):646-647. doi:10.1001/jama.2016.20826

Oxygen Supplementation Among Patients in the Intensive Care Unit

Abstract Full Text
JAMA. 2017;317(6):647-648. doi:10.1001/jama.2016.20829
Correction

Incorrect Values and Excluded Units of Measure

Abstract Full Text
free access
JAMA. 2017;317(6):648. doi:10.1001/jama.2017.0013

Omission of Data

Abstract Full Text
free access
JAMA. 2017;317(6):648. doi:10.1001/jama.2017.0040
Medical News & Perspectives

Unveiling the “Magic” of Diabetes Remission After Weight-Loss Surgery

Abstract Full Text
JAMA. 2017;317(6):571-574. doi:10.1001/jama.2017.0020

This Medical News article discusses theories explaining type 2 diabetes remission in patients who have undergone bariatric surgery.

The JAMA Forum

Mitochondrial Replacement Therapy: Unmade in the USA

Abstract Full Text
free access
JAMA. 2017;317(6):574-575. doi:10.1001/jama.2016.20935
Capitol Health Call

Concerns Over Newborn Screening

Abstract Full Text
JAMA. 2017;317(6):576. doi:10.1001/jama.2017.0080

Uncertain Future for Preexisting Conditions

Abstract Full Text
JAMA. 2017;317(6):576. doi:10.1001/jama.2017.0506

Cassidy Rolls Up His Sleeves

Abstract Full Text
JAMA. 2017;317(6):576. doi:10.1001/jama.2017.0508
News From the Centers for Disease Control and Prevention

Help Patients Have Smoke-Free Life

Abstract Full Text
JAMA. 2017;317(6):577. doi:10.1001/jama.2017.0098

Football’s Toll on Student Athletes

Abstract Full Text
JAMA. 2017;317(6):577. doi:10.1001/jama.2017.0100
The Arts and Medicine

The One With FriendsA TV Show Within a Play

Abstract Full Text
JAMA. 2017;317(6):568-569. doi:10.1001/jama.2016.20747

This Arts and Medicine essay reviews The One With Friends, a theatre workshop that addresses mental illness, loneliness, and the importance of human connection for young single adults through an imagined reunion of characters from the TV show Friends 10 years after the show ended.

Poetry and Medicine

Internal Rhythm

Abstract Full Text
JAMA. 2017;317(6):649. doi:10.1001/jama.2016.15751
JAMA Revisited

Philology and Pathology

Abstract Full Text
JAMA. 2017;317(6):650. doi:10.1001/jama.2016.20317
JAMA Patient Page

Chemotherapy and Hair Loss

Abstract Full Text
free access
JAMA. 2017;317(6):656. doi:10.1001/jama.2016.21266
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2017;317(6):559-560. doi:10.1001/jama.2016.12988
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