This randomized trial compares the effects of ventilator lung recruitment using PEEP titration vs a conventional low-PEEP strategy on 28-day mortality in patients with moderate to severe acute respiratory distress syndrome (ARDS).
This randomized clinical trial compares the effects of an individualized blood pressure management strategy vs standard blood pressure management strategy on postoperative organ dysfunction among high-risk patients undergoing major surgery.
This population-based cohort study compares rates of severe hypoglycemia and diabetic ketoacidosis among children, adolescents, and young adults with type 1 diabetes managed with insulin pump therapy vs insulin injection therapy.
This cohort study investigates associations between biomarkers of ovarian reserve and reproductive potential among women of late reproductive age.
This study examines assesses inappropriate antibiotic prescribing 12 months after stopping a randomized clinical trial of a behavioral intervention intended to reduce the rate of inappropriate antibiotic prescribing for acute respiratory infections.
This Viewpoint urges the use of clinical judgment and evidence-based standards when evaluating or testifying about child abuse injuries in light of a rise in unsubstantiated theories (such as vitamin D deficiency) that discount abuse as a cause of those injuries.
This Viewpoint discusses efforts by the health care industry to safeguard patient information from cyber attacks.
This Viewpoint discusses the risks posed by the merging of academic medical centers (AMCs) with nonacademic hospital networks and health systems to AMC investigators and the research enterprise.
This Viewpoint reviews recent research findings questioning the status of cognitive behavioral therapy as the gold standard for treating mental disorders.
This Users’ Guide to the Medical Literature discusses discrimination and calibration, 2 primary ways to measure and compare the accuracy of clinical risk prediction models.
This JAMA Clinical Guidelines Synopsis summarizes the 2016 practice guideline on management of diabetic foot sponsored by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine.
This Medical News story discusses 2 new toolkits aimed at helping primary care physicians detect, diagnose, and manage dementia in patients.
This Arts and Medicine essay reviews the 2016 independent feature film Black Women in Medicine, which chronicles the experiences of African American US female physicians.
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