This randomized clinical trial compares the effects of locking plate vs intramedullary nail fixation on disability, symptoms, and quality of life among patients with an acute displaced extra-articular distal tibia fracture.
This population-based epidemiology study uses Washington State birth and hospitalization data to assess the association between prepregnancy body mass index and severe morbidity or mortality during pregnancy.
This study uses data from Canadian administrative and clinical ambulatory databases to derive and validate risk prediction models for advanced chronic kidney disease in patients hosptialized with acute kidney injury.
This phase 2b randomized trial compares adverse events and efficacy of 3 doses of a peanut protein patch for the treatment of peanut sensitivity in patients aged 6 to 55 years.
This cross-sectional study uses NHANES survey data to examine trends in glycemic control and patient awareness of HbA1c test results and targets between 2007 and 2014.
This Viewpoint uses the October 2017 mass shooting in Las Vegas to discuss public health imperatives in the US firearm violence epidemic, including long-term treatment of nonfatally injured survivors, management of mental health sequelae for noninjured participants and their communities, and effective responses to commercial stakeholders who benefit from firearm sales at the expense of the public’s health.
This Viewpoint discusses a new FDA regulatory plan to reduce the burden of smoking-related disease by requiring reduction of nicotine in combustible tobacco products beneath addicting levels and by encouraging innovations in novel reduced-risk nicotine products.
In this Viewpoint, Anthony Fauci and colleagues review rapid research responses to recent infectious disease outbreaks as a way of emphasizing the strategies and collaborations necessary to prepare for a next unknown pandemic.
This Viewpoint discusses steps necessary to develop an all-payer hospital global budgeting system as one means to incentivize health systems to emphasize preventive care that reduces health service utilization and costs.
This Rational Clinical Examination systematic review summarizes the accuracy of available scoring instruments for diagnosing acute mountain sickness.
This JAMA Guide to Statistics and Methods reviews the use of composite outcome measures in clinical trials and discusses how their use should influence interpretations of trial results.
A 66-year-old man developed noninfectious fever and rash after autologous HSCT. Chest computed tomography showed ground-glass and consolidative lung opacities; skin punch biopsy showed vacuolar change and superficial perivascular mononuclear cell infiltrate. What would you do next?
The following Medical News story describes how bacteriophage therapy might help fight antibiotic resistant infections.
This Arts and Medicine essay discusses Heart Narratives, an art installation in the Great Ormond Street Hospital and Institute of Child Health in London that visualizes the illness narratives of children with congenital heart disease.
This JAMA Patient Page explains the symptoms, diagnosis, treatment, and prevention of acute mountain sickness.
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