[Skip to Navigation]
Sign In

May 2023 - July 1883




November 21, 2017, Vol 318, No. 19, Pages 1843-1945

In This Issue of JAMA


Abstract Full Text
free access has audio
JAMA. 2017;318(19):1843-1845. doi:10.1001/jama.2016.13399
Original Investigation

Effect of Sertraline on Depressive Symptoms in Patients With Chronic Kidney Disease Without Dialysis Dependence: The CAST Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2017;318(19):1876-1890. doi:10.1001/jama.2017.17131

This randomized clinical trial compares the effects of sertraline vs placebo on depressive symptoms in patients with stage 3, 4, or 5 non–dialysis-dependent chronic kidney disease and major depressive disorder.

Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2017;318(19):1891-1902. doi:10.1001/jama.2017.17070

This randomized trial tests the effects of oral insulin on time to new-onset type 1 diabetes in relatives of patients with type 1 diabetes with autoantibodies or impaired glucose tolerance..

Effect of an Indwelling Pleural Catheter vs Talc Pleurodesis on Hospitalization Days in Patients With Malignant Pleural Effusion: The AMPLE Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2017;318(19):1903-1912. doi:10.1001/jama.2017.17426

This randomized clinical trial determines whether indwelling pleural catheters are more effective than talc pleurodesis in reducing total hospitalization days in the remaining lifespan of patients with malignant pleural effusion.

Association of High-Sensitivity Cardiac Troponin I Concentration With Cardiac Outcomes in Patients With Suspected Acute Coronary Syndrome

Abstract Full Text
free access
JAMA. 2017;318(19):1913-1924. doi:10.1001/jama.2017.17488

This systematic review evaluates the performance of a cardiac troponin I threshold of 5 ng/L at presentation as a risk stratification tool in patients with suspected acute coronary syndrome.

Research Letter

Trends in Emergency Department Visits for Nonfatal Self-inflicted Injuries Among Youth Aged 10 to 24 Years in the United States, 2001-2015

Abstract Full Text
free access
JAMA. 2017;318(19):1931-1933. doi:10.1001/jama.2017.13317

This health services epidemiology study uses National Electronic Injury Surveillance System database data to characterize trends in hospital emergency department visits for nonfatal self-inflicted injuries among US youth aged 10 to 24 years from 2001 through 2015.


The Evolution of Patient Diagnosis: From Art to Digital Data-Driven Science

Abstract Full Text
JAMA. 2017;318(19):1859-1860. doi:10.1001/jama.2017.15028

This Viewpoint discusses how a clinical information commons, a health care system’s database of all its patient-based data, could make genetically based clinical diagnoses more scientific and potentially improve patient outcomes.

FDA Approval of Tisagenlecleucel: Promise and Complexities of a $475 000 Cancer Drug

Abstract Full Text
JAMA. 2017;318(19):1861-1862. doi:10.1001/jama.2017.15218

This Viewpoint uses FDA approval of tisagenlecleucel, the first chimeric antigen receptor T-cell (CAR-T) agent approved for human use, to discuss escalating drug prices for oncology therapies and the complex considerations of outcomes and value that should justify the pricing.

Measuring the Burden of Health Care Costs on US Families: The Affordability Index

Abstract Full Text
free access
JAMA. 2017;318(19):1863-1864. doi:10.1001/jama.2017.15686

This Viewpoint proposes a new Affordability Index measure, the ratio of the mean cost of an employer-sponsored family health insurance policy divided by median household income, to describe US families’ ability to pay for health care.

Addressing Population Health: Integrators in the Accountable Health Communities Model

Abstract Full Text
JAMA. 2017;318(19):1865-1866. doi:10.1001/jama.2017.15063

This Viewpoint discusses the Centers for Medicare & Medicaid Services’ Accountable Health Communities project to test the role of community integrators—organizations within a community that can represent its needs and engage stakeholders to work toward improvements in health—as a possible mechanism to decrease life expectancy disparities across the United States.

A Piece of My Mind

My Tenuous Relationship With an Octopus

Abstract Full Text
JAMA. 2017;318(19):1867-1868. doi:10.1001/jama.2017.15711

In this essay, the author describes his experience as an amputee to urge physicians to consider the whole patients beyond their disabilities as a way of building confidence that they can contribute and make a difference.


What Level of Health Spending Is “Affordable”?

Abstract Full Text
JAMA. 2017;318(19):1869-1870. doi:10.1001/jama.2017.16187

Challenges in Measuring the Affordability of US Health Care

Abstract Full Text
JAMA. 2017;318(19):1871-1872. doi:10.1001/jama.2017.16188

Treating Depression in Patients With Advanced CKD: Beyond the Generalizability Frontier

Abstract Full Text
JAMA. 2017;318(19):1873-1874. doi:10.1001/jama.2017.17553

Firearm-Related Injury and Death: A US Health Care Crisis in Need of Health Care Professionals

Abstract Full Text
free access
JAMA. 2017;318(19):1875. doi:10.1001/jama.2017.16692
JAMA Guide to Statistics and Methods

Mendelian Randomization

Abstract Full Text
has audio
JAMA. 2017;318(19):1925-1926. doi:10.1001/jama.2017.17219

This JAMA Guide to Statistics and Methods reviews the concepts underlying mendelian randomization and provides examples of its application to clinical trial design.

From the JAMA Network

Advancing High Performance in Veterans Affairs Health Care

Abstract Full Text
JAMA. 2017;318(19):1927-1928. doi:10.1001/jama.2017.17667

This commentary on a research letter published in JAMA Internal Medicine comparing the quality of care at Veterans Affairs (VA) vs non-VA hospitals discusses the systems the VA has in place to improve the health care of patients.

From The Medical Letter on Drugs and Therapeutics

Pancreatic Enzyme Replacement Products

Abstract Full Text
JAMA. 2017;318(19):1929. doi:10.1001/jama.2017.17384

This Medical Letter review summarizes the composition and dosing of commercially available pancreatic enzyme replacement products used to improve digestion in patients with exocrine pancreatic insufficiency.

Medical News & Perspectives

Loneliness Might Be a Killer, but What’s the Best Way to Protect Against It?

Abstract Full Text
has audio
JAMA. 2017;318(19):1853-1855. doi:10.1001/jama.2017.14591

This Medical News article discusses the health implications of loneliness and interventions to build emotional support.

News From the Food and Drug Administration

Relief for Central Sleep Apnea

Abstract Full Text
JAMA. 2017;318(19):1858. doi:10.1001/jama.2017.17118

Twice the Power in New MRI

Abstract Full Text
JAMA. 2017;318(19):1858. doi:10.1001/jama.2017.17120

Eye Tracking in Surgical Robotics

Abstract Full Text
JAMA. 2017;318(19):1858. doi:10.1001/jama.2017.17121
The JAMA Forum

Building Blocks for Addressing Social Determinants of Health

Abstract Full Text
free access
JAMA. 2017;318(19):1855-1856. doi:10.1001/jama.2017.16493
Global Health

Two Southeast Asian Countries Eliminate Trachoma

Abstract Full Text
JAMA. 2017;318(19):1857. doi:10.1001/jama.2017.16426

High Mercury Levels Found in Women Around the World

Abstract Full Text
JAMA. 2017;318(19):1857. doi:10.1001/jama.2017.17516

Child Mortality Rates Decrease in India

Abstract Full Text
JAMA. 2017;318(19):1857. doi:10.1001/jama.2017.17518
Poetry and Medicine

Post Vitreous Detachment

Abstract Full Text
JAMA. 2017;318(19):1938. doi:10.1001/jama.2017.7269
JAMA Revisited

The Soldiers’ and Sailors’ Insurance Law

Abstract Full Text
JAMA. 2017;318(19):1939. doi:10.1001/jama.2017.10495
JAMA Patient Page

Treatments for Food Allergies

Abstract Full Text
free access has multimedia
JAMA. 2017;318(19):1945. doi:10.1001/jama.2017.17306

This JAMA Patient Page summarizes the most common food allergies and the immunotherapy options available for desensitization to food allergens.

Comment & Response

Consequences of Reductions in Hospital Readmissions

Abstract Full Text
JAMA. 2017;318(19):1933-1934. doi:10.1001/jama.2017.14779

Consequences of Reductions in Hospital Readmissions—Reply

Abstract Full Text
JAMA. 2017;318(19):1934. doi:10.1001/jama.2017.14799

Patient-Reported Symptom Monitoring During Chemotherapy

Abstract Full Text
JAMA. 2017;318(19):1935. doi:10.1001/jama.2017.14899

Patient-Reported Symptom Monitoring During Chemotherapy—Reply

Abstract Full Text
JAMA. 2017;318(19):1935-1936. doi:10.1001/jama.2017.14903

Medical Device Identification in Claims Data

Abstract Full Text
JAMA. 2017;318(19):1936-1937. doi:10.1001/jama.2017.15146

Medical Device Identification in Claims Data—Reply

Abstract Full Text
JAMA. 2017;318(19):1937. doi:10.1001/jama.2017.15161

Incorrect Unit of Measure

Abstract Full Text
free access
JAMA. 2017;318(19):1937. doi:10.1001/jama.2017.16959

Data Error, Missing Sentence, and Misnumbered References

Abstract Full Text
free access
JAMA. 2017;318(19):1937. doi:10.1001/jama.2017.17015
JAMA Masthead


Abstract Full Text
free access
JAMA. 2017;318(19):1847-1848. doi:10.1001/jama.2016.13400