This randomized clinical trial compares the effects on symptom remission of switching to bupropion, adding bupropion, or adding aripiprazole to baseline treatment among Veterans Affairs patients with antidepressant-resistant major depressive disorder.
This Swedish cohort study investigates whether treatment with alendronate is associated with reduced risk of hip fracture among older patients using oral glucocorticoids.
This systematic review analyzes 10 randomized clinical trials comparing the effects of positive airway pressure (PAP) vs sham PAP in reducing cardiovascular outcomes or death among patients with sleep apnea.
This study assesses overall survival associated with electronic patient-reported symptom monitoring vs usual care during routine cancer treatment.
This Recommendation Statement from the US Preventive Services Task Force recommends that primary care professionals individualize the decision to refer adults without obesity and cardiovascular risk factors to behavioral counseling to promote healthful diet and physical activity (C recommendation).
This Evidence Report and systematic review to support a 2017 US Preventive Services Task Force Recommendation Statement summarizes current evidence on benefits and harms of behavioral counseling for primary prevention of cardiovascular disease (CVD) in adults without known CVD risk factors.
This Viewpoint describes the structure and outcomes of a national initiative of the Centers for Medicare & Medicaid Services to reduce the use of antipsychotics in nursing homes.
This Viewpoint discusses the management of antiplatelet therapy in patients with coronary stents undergoing elective noncardiac surgery.
This Viewpoint urges all medical and health professional training programs to make social mission a central curricular focus to help evenly distribute health care and to eliminate health disparities among patients who have little means and access to health care.
This commentary discusses a study published in JAMA Cardiology that assessed the prognosis of cardiovascular and bleeding events associated with dual antiplatelet therapy continued beyond a year after coronary stenting.
This Medical News article discusses research exploring the clinical potential of a chemically modified dietary starch to protect against type 1 diabetes and other diseases.