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November 2018 - July 1883

Decade

Year

Issue

December 12, 2017, Vol 318, No. 22, Pages 2155-2265

In This Issue of JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2017;318(22):2155-2157. doi:10.1001/jama.2016.13434
Viewpoint

Advance Directives for DementiaMeeting a Unique Challenge

Abstract Full Text
JAMA. 2017;318(22):2175-2176. doi:10.1001/jama.2017.16473

This Viewpoint discusses the unique challenges of crafting meaningful advance directives for patients with dementia and proposes a framework that accounts for changes in goals of care that might occur along the continuum of cognitive decline.

Organ Donor ResearchOvercoming Challenges, Increasing Opportunities

Abstract Full Text
JAMA. 2017;318(22):2177-2178. doi:10.1001/jama.2017.16442

This Viewpoint discusses a 2017 National Academies of Sciences, Engineering, and Medicine report about ways to support research on pretransplantation organs to reduce organ waste, upgrade the quality and quantity of transplants, and improve patient outcomes.

Contraceptive Coverage and the Balance Between Conscience and Access

Abstract Full Text
JAMA. 2017;318(22):2179-2180. doi:10.1001/jama.2017.17086

This Viewpoint discusses the Trump administration’s 2017 change to ACA provisions, which exempts employers with religious or moral objections to contraception from including coverage for contraceptives in their insurance plans.

High Costs of FDA Approval for Formerly Unapproved Marketed Drugs

Abstract Full Text
JAMA. 2017;318(22):2181-2182. doi:10.1001/jama.2017.16481

This Viewpoint describes how the US Food and Drug Administration’s 2006 Unapproved Drugs Initiative may have unintentionally made generic drugs more expensive and inaccessible and proposes policy reforms to address the harms of those price increases.

A Piece of My Mind

A Fair Interpretation

Abstract Full Text
JAMA. 2017;318(22):2183. doi:10.1001/jama.2017.17563

In this essay, the author urges precision language when referring to foreign language interpreters as a recognition that words outside of medicine mean something too.

Editorial

Deep Learning Algorithms for Detection of Lymph Node Metastases From Breast CancerHelping Artificial Intelligence Be Seen

Abstract Full Text
has multimedia has audio
JAMA. 2017;318(22):2184-2186. doi:10.1001/jama.2017.14580

Menopausal Hormone Therapy for Primary Prevention of Chronic Disease

Abstract Full Text
JAMA. 2017;318(22):2187-2189. doi:10.1001/jama.2017.16974
Original Investigation

Effect of Levothyroxine on Miscarriage Among Women With Normal Thyroid Function and Thyroid Autoimmunity Undergoing In Vitro Fertilization and Embryo TransferA Randomized Clinical Trial

Abstract Full Text
free access has active quiz
JAMA. 2017;318(22):2190-2198. doi:10.1001/jama.2017.18249

This randomized clinical trial compares the effects of levothyroxine vs placebo on pregnancy outcomes among women with normal thyroid function and positive antithyroperoxidase antibodies undergoing in vitro fertilization and embryo transfer in Beijing, China.

Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer

Abstract Full Text
free access has active quiz
JAMA. 2017;318(22):2199-2210. doi:10.1001/jama.2017.14585

This diagnostic accuracy study compares the ability of machine learning algorithms vs clinical pathologists to detect cancer metastases in whole-slide images of axillary lymph nodes dissected from women with breast cancer.

Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes

Abstract Full Text
free access
JAMA. 2017;318(22):2211-2223. doi:10.1001/jama.2017.18152

This diagnostic accuracy study compares the performance of deep learning systems vs eye professionals for detecting referable and vision-threatening diabetic retinopathy, glaucoma, and other eye diseases in retinal images from Chinese, Indian, and Malaysian patients.

US Preventive Services Task Force

Recommendation Statement

Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal WomenUS Preventive Services Task Force Recommendation Statement

Abstract Full Text
free access has active quiz has audio
JAMA. 2017;318(22):2224-2233. doi:10.1001/jama.2017.18261

This Recommendation Statement from the US Preventive Services Task Force recommends against use of hormone therapy for primary prevention of chronic conditions in postmenopausal women (D recommendation).

Evidence Report

Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal WomenEvidence Report and Systematic Review for the US Preventive Services Task Force

Abstract Full Text
free access
JAMA. 2017;318(22):2234-2249. doi:10.1001/jama.2017.16952

This systematic review to support the 2017 update of the US Preventive Services Task Force Recommendation Statement on use of hormone therapy summarizes published evidence on the benefits and harms of hormone therapy for primary prevention of chronic conditions in postmenopausal women.

JAMA Guide to Statistics and Methods

Using Free-Response Receiver Operating Characteristic Curves to Assess the Accuracy of Machine Diagnosis of Cancer

Abstract Full Text
JAMA. 2017;318(22):2250-2251. doi:10.1001/jama.2017.18686

This JAMA Guide to Statistics and Methods discusses the use of free-response receiver operating characteristic curves to test the accuracy of computer algorithms to detect the localization of disease on pathology slide images.

Research Letter

Availability of Pharmacist-Prescribed Contraception in California, 2017

Abstract Full Text
free access
JAMA. 2017;318(22):2253-2254. doi:10.1001/jama.2017.15674

This survey study estimates the extent to which pharmacies in California are making pharmacist-prescribed contraception available since it was permitted, but not required, in April 2016.

Medical News & Perspectives

The Promise and Challenges of CAR-T Gene Therapy

Abstract Full Text
JAMA. 2017;318(22):2167-2169. doi:10.1001/jama.2017.15605

This Medical News article discusses the promise and challenges of CAR-T therapies.

Can Exercise Prevent Knee Osteoarthritis?

Abstract Full Text
JAMA. 2017;318(22):2169-2171. doi:10.1001/jama.2017.16144

This Medical News article discusses whether sedentary lifestyles contribute to this increasingly prevalent degenerative joint disease.

The JAMA Forum

Five Ethical Values to Guide Health System Reform

Abstract Full Text
free access
JAMA. 2017;318(22):2171-2172. doi:10.1001/jama.2017.18804
News From the Centers for Disease Control and Prevention

Illicit Fentanyl Driving Opioid Overdose Deaths

Abstract Full Text
JAMA. 2017;318(22):2174. doi:10.1001/jama.2017.18602

More Than 1 in 5 Working Adults Use Some Form of Tobacco

Abstract Full Text
JAMA. 2017;318(22):2174. doi:10.1001/jama.2017.18931
Biotech Innovations

Point-of-Use Food Allergen Detector on the Horizon

Abstract Full Text
JAMA. 2017;318(22):2173. doi:10.1001/jama.2017.18651

DNA Base Editing Could Reverse Most Disease-Causing Point Mutations

Abstract Full Text
JAMA. 2017;318(22):2173. doi:10.1001/jama.2017.19063

First Phase 1 Trial of a Prophylactic mRNA Vaccine Reported

Abstract Full Text
JAMA. 2017;318(22):2173. doi:10.1001/jama.2017.19065
Comment & Response

Radiofrequency Denervation for Chronic Low Back Pain

Abstract Full Text
JAMA. 2017;318(22):2254-2255. doi:10.1001/jama.2017.16386

Radiofrequency Denervation for Chronic Low Back Pain

Abstract Full Text
JAMA. 2017;318(22):2255-2256. doi:10.1001/jama.2017.16378

Radiofrequency Denervation for Chronic Low Back Pain

Abstract Full Text
JAMA. 2017;318(22):2256. doi:10.1001/jama.2017.16382

Radiofrequency Denervation for Chronic Low Back Pain—Reply

Abstract Full Text
JAMA. 2017;318(22):2256-2257. doi:10.1001/jama.2017.16390

Contact Precautions for Multidrug-Resistant Organisms

Abstract Full Text
JAMA. 2017;318(22):2257. doi:10.1001/jama.2017.16671

Humane Language for People in the Criminal Justice System

Abstract Full Text
JAMA. 2017;318(22):2258-2259. doi:10.1001/jama.2017.16563

Contact Precautions for Multidrug-Resistant Organisms—Reply

Abstract Full Text
JAMA. 2017;318(22):2258. doi:10.1001/jama.2017.16679

Humane Language for People in the Criminal Justice System—Reply

Abstract Full Text
JAMA. 2017;318(22):2259. doi:10.1001/jama.2017.16567
The Arts and Medicine

From Sgt. Pepper to Dreamachines: My Scientific Odyssey With William S. Burroughs

Abstract Full Text
has multimedia
JAMA. 2017;318(22):2164-2166. doi:10.1001/jama.2017.17914

This Arts and Medicine essay explores the relevance of writer and artist William S. Burroughs to clinical medicine, and his importance to the author’s career as a Parkinson disease researcher.

Poetry and Medicine

Old Veins

Abstract Full Text
JAMA. 2017;318(22):2260. doi:10.1001/jama.2017.4226
JAMA Revisited

The Banana Again

Abstract Full Text
JAMA. 2017;318(22):2261. doi:10.1001/jama.2017.10498
JAMA Patient Page

Hormone Therapy for Primary Prevention of Chronic Conditions in Postmenopausal Women

Abstract Full Text
free access
JAMA. 2017;318(22):2265. doi:10.1001/jama.2017.18440

This JAMA Patient Page describes the US Preventive Services Task Force’s recommendations on use of hormone therapy for primary prevention of chronic conditions in postmenopausal women.

JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2017;318(22):2159-2160. doi:10.1001/jama.2016.13435
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