This randomized trial compares the effects of tumor-treating fields plus temozolomide vs temozolomide alone on progression-free and overall survival in patients with glioblastoma who had undergone resection or biopsy and radiochemotherapy.
This randomized clinical trial compares the effect of use of a cervival pessary vs usual care on risk of spontaneous preterm birth among women with singleton pregnancies without prior spontaneous preterm birth but with short cervical length.
This cohort study compares the effects of broad- vs narrow-spectrum antibiotics on clinical and patient-centered outcomes among children treated for acute respiratory tract infection in primary care pediatric practices.
This survey study estimates suicide risk behaviors of sexual minority adolescents using National Youth Risk Behavior Survey data from 2015.
This reporting guideline recommends a minimum set of 55 items that should be addressed and included in statistical analysis plans for clinical trials.
This Viewpoint explains the rationale behind the contractual agreement that residency applicants sign when they participate in the National Resident Matching Program and describes processes the program follows when applicants do not or cannot honor the agreement.
This Viewpoint reviews the contribution of housing instability to health care outcomes and costs and proposes ways hospitals and health systems could address homelessness to prevent the health problems that result from it.
This Viewpoint reviews the causes of homelessness and models and programs that have been effective at housing homeless people and families, and proposes roles hospitals and health systems might play in addressing the problem.
In this Viewpoint, authors from the US CDC’s National Center for Injury Prevention and Control discuss infrastructure investments, legal changes, and clinical and public health strategies for reducing overdose deaths among opioid users.
This essay relies on the metaphor of the erosion of shorelines to guide medical students, residents, and physicians to understand the reshaping through the erosive forces inherent with the professional formation of a medical career.
This commentary discusses a review published in JAMA Otolaryngology–Head & Neck Surgery that used a Canadian population-based health care administrative database to characterize rates of use of topical intranasal steroid therapy for chronic rhinosinusitis.
This JAMA Clinical Guidelines Synopsis summarizes the 2016 US Multi-Society Task Force on Colorectal Cancer’s guideline on colonoscopy surveillance after colorectal cancer resection.
This Medical News article discusses the ongoing efforts to assess and mitigate chemical toxin exposure in the wake of Hurricane Harvey.
This Medical News article examines a proposal to create a nonpartisan panel that would evaluate US presidents’ mental and physical fitness to serve.
This Art and Medicine essay reviews the 2 best graphic medicine novels of 2017: Last Things by Marissa Moss, about her husband’s decline from ALS; and Taking Turns by MK Czerwiec, about a Chicago inpatient AIDS unit.
This JAMA Patient Page explains the prevention, transmission, symptoms, and treatment of hepatitis A.
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