This randomized clinical trial evaluated the effectiveness and safety of oral methylprednisolone vs placebo in patients with IgA nephropathy and proteinuria.
This randomized trial compares the effects of thrombectomy with a contact aspiration vs a stent retriever technique on successful endovascular revascularization in patients with acute ischemic stroke.
This cross-sectional study assesses whether physician practices serving more socially high-risk and medically high-risk patients are associated with performance in the Medicare Physician Value-Based Payment Modifier Program.
This study investigates fees charged to physicians for certification examinations and finances of the American Board of Medical Specialties member boards.
This Viewpoint clarifies 3 treatment options for treating patients with elevated cholesterol levels by discussing patient goals, encouraging lifestyle changes, and using lipid-lowering medication.
This Viewpoint discusses variances in cardiovascular prevention guidelines from the United States, Europe, and Canada and the debate surrounding low-density lipoprotein levels as the primary focus.
In this Viewpoint, FDA Commissioner Scott Gottlieb and CDER Director Janet Woodcock discuss how the FDA weighs the risks and benefits of opioids and integrates public health and clinical perspectives into decisions about opioid approval, marketing, restrictions, and labeling.
This Viewpoint describes the National Academies of Sciences, Engineering, and Medicine’s new report on the harms associated with opioid misuse and the effects of strategies to reduce those harms, and discusses the importance of balancing patients’ pain management and addressing the current opioid epidemic.
This Viewpoint from the acting director of the CDC and coauthors reports data on opioid prescribing and related misuse and overdose-related deaths for the period 2006-2015 in the United States.
This systematic review analyzes 23 cohort studies to assess the accuracy of individual symptoms and physical examination findings for the diagnosis of radiographic pneumonia in children.
This commentary discusses a narrative review published in JAMA Pediatrics that summarized the rationale historically used to support respiratory viral testing in children and the potential considerations and limitations of the various types of tests.
A 29-year-old man presented with recurrent nephrolithiasis with 95% calcium oxalate and 5% calcium phosphate. His maternal family history was significant for nephrolithiasis, but his laboratory studies showed normal results. How would you proceed?
This Medical News article discusses recent programs and initiatives aimed at better integrating genomic data into clinical practice.