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May 2023 - July 1883




April 3, 2018, Vol 319, No. 13, Pages 1293-1405

In This Issue of JAMA


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JAMA. 2018;319(13):1293-1295. doi:10.1001/jama.2017.12306
Original Investigation

Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention on Major Adverse Cardiovascular Events in Acute Coronary Syndrome: The SECURE-PCI Randomized Clinical Trial

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JAMA. 2018;319(13):1331-1340. doi:10.1001/jama.2018.2444

This randomized trial compares the effects of a periprocedural loading dose of atorvastatin vs placebo on major adverse cardiovascular events (MACE) at 30 days in patients with acute coronary syndrome (ACS) and planned percutaneous coronary intervention (PCI).

Association of a Negative Wealth Shock With All-Cause Mortality in Middle-aged and Older Adults in the United States

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JAMA. 2018;319(13):1341-1350. doi:10.1001/jama.2018.2055

This study investigated mortality of participants in the Heart and Retirement Study who experienced negative wealth shock from 1994 through 2014.

Association of Solid Fuel Use With Risk of Cardiovascular and All-Cause Mortality in Rural China

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JAMA. 2018;319(13):1351-1361. doi:10.1001/jama.2018.2151

This cohort study conducted in 5 rural areas across China examines associations between solid fuel use for cooking and heating and cardiovascular and all-cause mortality.

Research Letter

Mortality From Falls in Dutch Adults 80 Years and Older, 2000-2016

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JAMA. 2018;319(13):1380-1382. doi:10.1001/jama.2018.1444

This study uses national statistics to characterize trends in mortality from falls in persons aged 80 years and older between 2000 and 2016 in the Netherlands.


Institutional Research Misconduct Reports Need More Credibility

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JAMA. 2018;319(13):1315-1316. doi:10.1001/jama.2018.0358

This Viewpoint highlights the inadequacy and lack of transparency of most research institutions’ responses to allegations of research misconduct, and describes development of a proposed checklist to establish definitions and standards for complete research integrity investigations.

Big Data and Machine Learning in Health Care

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JAMA. 2018;319(13):1317-1318. doi:10.1001/jama.2017.18391

This Viewpoint discusses how newer technologies such as machine learning and the compilation of “big data” can be used for research and clinical applications.

Individualizing Blood Pressure Targets for People With Diabetes and Hypertension: Comparing the ADA and the ACC/AHA Recommendations

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JAMA. 2018;319(13):1319-1320. doi:10.1001/jama.2018.0642

This Viewpoint compares and contrasts recommendations from the 2017 ADA and ACC/AHA guidelines for management of high blood pressure and argues for individualization of patient goals and blood pressure targets.

Can Small Physician Practices Survive?Sharing Services as a Path to Viability

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JAMA. 2018;319(13):1321-1322. doi:10.1001/jama.2017.21704

This Viewpoint discusses the use of shared service arrangements as a means for small physician practices to pool and manage resources, stay competitive for value-based contracts, and remain viable in the face of market forces favoring consolidation.

A Piece of My Mind

Sharing Connections

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JAMA. 2018;319(13):1323-1324. doi:10.1001/jama.2018.2717

In this essay, the author uses her experience helping vulnerable patients in Houston, Texas, following Hurricane Harvey in 2017, via a computer screen in San Diego, to argue for the importance of telemedicine as a way to scale up care to manage the acute needs of patients and populations caught in natural disasters.


Lipid Lowering in Acute Coronary Syndrome: Is Treatment Early Enough?

Abstract Full Text
JAMA. 2018;319(13):1325-1326. doi:10.1001/jama.2018.2426

From Misfortune to Mortality: Sudden Loss of Wealth and Increased Risk of Death

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JAMA. 2018;319(13):1327-1328. doi:10.1001/jama.2018.3418

To JAMA Authors, Reviewers, and Readers—Thank You

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JAMA. 2018;319(13):1329-1330. doi:10.1001/jama.2018.3775

Neonatal Abstinence Syndrome: Advances in Diagnosis and Treatment

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JAMA. 2018;319(13):1362-1374. doi:10.1001/jama.2018.2640

This narrative review summarizes advances in diagnosis and in pharmacologic and nonpharmacologic management of neonatal abstinence syndrome.

JAMA Clinical Guidelines Synopsis

Evaluation and Treatment of Male Hypogonadism

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JAMA. 2018;319(13):1375-1376. doi:10.1001/jama.2018.3182

This JAMA Clinical Guidelines Synopsis summarizes the 2018 Endocrine Society guideline on testosterone therapy in men with testosterone deficiency and hypogonadism..

JAMA Diagnostic Test Interpretation

Evaluation of the Direct Antiglobulin Test (DAT) in the Setting of Mycoplasma pneumoniae Infection

Abstract Full Text
JAMA. 2018;319(13):1377-1378. doi:10.1001/jama.2018.1969

A young adult with community-acquired Mycoplasma pneumonia was found to have new-onset anemia, thrombocytosis, positive direct antiglobulin testing for anti-C3, and red blood cell agglutination at 4°C and at room temperature. How would you interpret these results?

Medical News & Perspectives

Chronic Disease Approaches Needed to Curb Gout’s Growing Burden

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JAMA. 2018;319(13):1307-1309. doi:10.1001/jama.2018.0547

This Medical News story discusses clinical approaches in the treatment of gout.

Experimental Device Could Offer Hope for Millions With Tinnitus

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JAMA. 2018;319(13):1309-1310. doi:10.1001/jama.2018.1047

In this Medical News story, researchers discuss an experimental device that uses a novel approach to relieve symptoms of somatic tinnitus.

News From the Food and Drug Administration

Reducing Lung Cancer Progression With Immunotherapy

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JAMA. 2018;319(13):1314. doi:10.1001/jama.2018.2928

New Stent for Small Vessels

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JAMA. 2018;319(13):1314. doi:10.1001/jama.2018.2942

Another Caution for Clarithromycin

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JAMA. 2018;319(13):1314. doi:10.1001/jama.2018.2945
The JAMA Forum

Income, Poverty, and Health Inequality

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JAMA. 2018;319(13):1312-1313. doi:10.1001/jama.2018.2521
Bench to Bedside

Platelets’ Role in Adaptive Immunity May Contribute to Sepsis and Shock

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JAMA. 2018;319(13):1311-1312. doi:10.1001/jama.2017.12859
The Arts and Medicine

Artistic Renaissance in Frontotemporal Dementia

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JAMA. 2018;319(13):1304-1306. doi:10.1001/jama.2017.19501

This Arts and Medicine essay uses case descriptions of 2 patients who experienced a sudden increase in artistic creativity with the onset of frontotemporal dementia to discuss the mechanism of paradoxical functional facilitation, in which loss of activity in one part of the brain leads to release of activity in another.

Poetry and Medicine


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JAMA. 2018;319(13):1387. doi:10.1001/jama.2017.15677
JAMA Revisited

The Ethics of Surgery

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JAMA. 2018;319(13):1388. doi:10.1001/jama.2017.12314
Peer Reviewers List

JAMA Peer Reviewers in 2017

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JAMA. 2018;319(13):1389-1400. doi:10.1001/jama.2018.2441
JAMA Patient Page

Skin Abscess

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JAMA. 2018;319(13):1405. doi:10.1001/jama.2018.1355

This JAMA Patient Page describes skin abscess—its symptoms, treatment, and warning signs.

Comment & Response

Interventions to Prevent Falls in Older Adults

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JAMA. 2018;319(13):1382. doi:10.1001/jama.2018.0204

Interventions to Prevent Falls in Older Adults—Reply

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JAMA. 2018;319(13):1382-1383. doi:10.1001/jama.2018.0224

Continuous Glucose Monitors for Insulin Dosing

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JAMA. 2018;319(13):1383. doi:10.1001/jama.2018.0185

Glyphosate Levels in Older Adults

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JAMA. 2018;319(13):1384-1385. doi:10.1001/jama.2018.0208

Continuous Glucose Monitors for Insulin Dosing—Reply

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JAMA. 2018;319(13):1384. doi:10.1001/jama.2018.0212

Glyphosate Levels in Older Adults—Reply

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JAMA. 2018;319(13):1385. doi:10.1001/jama.2018.0216

Undisclosed Conflicts of Interest

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JAMA. 2018;319(13):1385-1386. doi:10.1001/jama.2018.2950

Undisclosed Conflicts of Interest

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JAMA. 2018;319(13):1386. doi:10.1001/jama.2018.2732

Units of Measure Error

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JAMA. 2018;319(13):1386. doi:10.1001/jama.2018.2977
JAMA Masthead


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JAMA. 2018;319(13):1297-1298. doi:10.1001/jama.2017.12307