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July 2019 - July 1883

Decade

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Issue

January 9, 2018, Vol 319, No. 2, Pages 103-202

In This Issue of JAMA

Highlights

Abstract Full Text
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JAMA. 2018;319(2):103-105. doi:10.1001/jama.2017.12185
Original Investigation

Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials

Abstract Full Text
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JAMA. 2018;319(2):130-142. doi:10.1001/jama.2017.20373

This report describes findings from 3 randomized trials comparing the cognitive effects of 10, 30, or 60 mg/d of idalopirdine added to stable cholinesterase inhibitor treatment or placebo for symptomatic treatment of mild to moderate Alzheimer disease.

Association Between Handover of Anesthesia Care and Adverse Postoperative Outcomes Among Patients Undergoing Major Surgery

Abstract Full Text
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JAMA. 2018;319(2):143-153. doi:10.1001/jama.2017.20040

This cohort study uses Canadian administrative health care data to investigate associations between handover of intraoperative anesthesia care between one physician and another and risk of adverse postoperative outcomes among patients undergoing major surgery.

Association of Screening and Treatment With Breast Cancer Mortality by Molecular Subtype in US Women, 2000-2012

Abstract Full Text
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JAMA. 2018;319(2):154-164. doi:10.1001/jama.2017.19130

This simulation study estimates reductions in breast cancer mortality associated with screening and treatment by estrogen-receptor and human epidermal growth factor receptor 2 (ERBB2) status.

Research Letter

Participation and Dropout in the Bundled Payments for Care Improvement Initiative

Abstract Full Text
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JAMA. 2018;319(2):191-193. doi:10.1001/jama.2017.14771

This study describes hospital participation and dropout in the Centers for Medicare & Medicaid Innovation’s Bundled Payments for Care Improvement Initiative, which allows hospitals and practices to retain savings if they meet quality targets.

US Preventive Services Task Force

Recommendation Statement

Screening for Adolescent Idiopathic Scoliosis: US Preventive Services Task Force Recommendation Statement

Abstract Full Text
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JAMA. 2018;319(2):165-172. doi:10.1001/jama.2017.19342

This Recommendation Statement from the US Preventive Services Task Force concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for adolescent idiopathic scoliosis in children and adolescents aged 10 to 18 years (I statement).

Evidence Report

Screening for Adolescent Idiopathic Scoliosis: Evidence Report and Systematic Review for the US Preventive Services Task Force

Abstract Full Text
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JAMA. 2018;319(2):173-187. doi:10.1001/jama.2017.11669

This systematic review to support the 2018 update of the US Preventive Services Task Force Recommendation Statement on screening for adolescent idiopathic scoliosis (AIS) summarizes published evidence on the benefits and harms of AIS screening and treatment for children and adolescents aged 10 to 18 years.

Viewpoint

Diagnosis and Treatment of Hypertension in the 2017 ACC/AHA Guidelines and in the Real World

Abstract Full Text
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JAMA. 2018;319(2):115-116. doi:10.1001/jama.2017.19672

In this Viewpoint, John Ioannidis discusses implications of the 2017 hypertension guidelines for real-world management of blood pressure (BP), including labeling healthy people as having disease and possible adverse treatment effects at lower BP treatment targets..

Cardiovascular Guideline Skepticism vs Lifestyle Realism?

Abstract Full Text
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JAMA. 2018;319(2):117-118. doi:10.1001/jama.2017.19675

This Viewpoint discusses practical applications of the recent 2017 ACC?AHA guidelines on hypertension management and the importance of emphasizing healthier lifestyles in the United States.

Funding Innovation in a Learning Health Care System

Abstract Full Text
JAMA. 2018;319(2):119-120. doi:10.1001/jama.2017.18205

This Viewpoint discusses reforms to federal funding strategies and systems that might incentivize health care delivery innovation and create learning health care systems focused on improving health more than financial outcomes.

A Piece of My Mind

She Smiled as She Walked Away

Abstract Full Text
JAMA. 2018;319(2):121-122. doi:10.1001/jama.2017.19760

In this humanities essay, a former combat medic recalls an encounter with a patient whose smile and calm demeanor belied acute physical signs of torture.

Editorial

Lack of Benefit With Idalopirdine for Alzheimer Disease: Another Therapeutic Failure in a Complex Disease Process

Abstract Full Text
JAMA. 2018;319(2):123-125. doi:10.1001/jama.2017.19700

Handovers During Anesthesia Care: Patient Safety Risk or Opportunity for Improvement?

Abstract Full Text
JAMA. 2018;319(2):125-127. doi:10.1001/jama.2017.20602

Evolving Recommendations for Scoliosis Screening: A Compelling Need for Further Research

Abstract Full Text
JAMA. 2018;319(2):127-129. doi:10.1001/jama.2017.20190
From The Medical Letter on Drugs and Therapeutics

Lesinurad/Allopurinol (Duzallo) for Gout-Associated Hyperuricemia

Abstract Full Text
JAMA. 2018;319(2):188-189. doi:10.1001/jama.2017.20189

This Medical Letter review summarizes the mechanism of action and adverse effects of combination lesinurad, an uric acid transporter 1, and allopurinol, a xanthine oxidase inhibitor, for treatment of gout-associated hyperuricemia in patients who have not achieved target serum uric acid levels with allopurinol alone.

Medical News & Perspectives

Why Are American Indians Dying Young?

Abstract Full Text
JAMA. 2018;319(2):109-111. doi:10.1001/jama.2017.10122

This Medical News article discusses data on American Indian and Alaska Native premature mortality and its causes.

News From the Centers for Disease Control and Prevention

Nearly 15% of US HIV Infections Undiagnosed in 2015

Abstract Full Text
JAMA. 2018;319(2):114. doi:10.1001/jama.2017.20149

High Cost of Investigating Measles Cases

Abstract Full Text
JAMA. 2018;319(2):114. doi:10.1001/jama.2017.20423
Biotech Innovations

iPhone–Based Device Helps Treat River Blindness

Abstract Full Text
JAMA. 2018;319(2):113. doi:10.1001/jama.2017.20077

Clinical Advances in Human Gene Therapies

Abstract Full Text
JAMA. 2018;319(2):113. doi:10.1001/jama.2017.20692
JAMA Infographic

Mortality Among American Indians and Alaska Natives

Abstract Full Text
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JAMA. 2018;319(2):112. doi:10.1001/jama.2017.20760
Poetry and Medicine

One Minute

Abstract Full Text
JAMA. 2018;319(2):196. doi:10.1001/jama.2017.13821
JAMA Revisited

Book Notices

Abstract Full Text
JAMA. 2018;319(2):197. doi:10.1001/jama.2017.12193
JAMA Patient Page

Screening for Scoliosis in Adolescents

Abstract Full Text
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JAMA. 2018;319(2):202. doi:10.1001/jama.2017.20372

This JAMA Patient Page discusses the US Preventive Services Task Force’s recommendations on screening for adolescent idiopathic scoliosis.

Comment & Response

Menopausal Estrogen Therapy and Breast Cancer Mortality

Abstract Full Text
JAMA. 2018;319(2):193. doi:10.1001/jama.2017.18308

Menopausal Estrogen Therapy and Breast Cancer Mortality—Reply

Abstract Full Text
JAMA. 2018;319(2):193-194. doi:10.1001/jama.2017.18316

Dermoscopic Patterns of Spitz Nevi

Abstract Full Text
JAMA. 2018;319(2):194. doi:10.1001/jama.2017.18991

Dermoscopic Patterns of Spitz Nevi—Reply

Abstract Full Text
JAMA. 2018;319(2):194. doi:10.1001/jama.2017.18999

Improving Diagnostic Decisions

Abstract Full Text
JAMA. 2018;319(2):195. doi:10.1001/jama.2017.17716

Improving Diagnostic Decisions—Reply

Abstract Full Text
JAMA. 2018;319(2):195. doi:10.1001/jama.2017.17732
Correction

Error in Affiliation

Abstract Full Text
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JAMA. 2018;319(2):195. doi:10.1001/jama.2017.20093

Factual Error

Abstract Full Text
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JAMA. 2018;319(2):195. doi:10.1001/jama.2017.20672
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2018;319(2):107-108. doi:10.1001/jama.2017.12186
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