This randomized clinical trial compares the effects of 2 vitamin D dosing strategies on recurrent wheezing in black infants at 12months of age who were born preterm.
This randomized controlled trial compares the effects of high- vs low-frequency computed tomographic and carcinoembryonic antigen surveillance on 5-year overall mortality and colorectal cancer–specific mortality rates among patients with stage II and II colorectal cancer after curative resection.
This cohort study uses medical record data to compare disease recurrence among patients with stages I, II, or III colorectal cancer monitored with higher- vs lower-intensity imaging and CEA surveillance testing within 3 years after treatment.
This cohort study uses administrative data from a large US database to evaluate whether surgical occlusion of the left atrial appendage (LAAO) during CABG or valve surgery is associated with risk of stroke, mortality, and atrial fibrillation.
This study characterizes the sources of funding for the research included in systematic reviews that form the basis for US Preventive Services Task Force recommendation statements.
This Viewpoint uses the observation that ondansetron has been found to reduce symptoms of opioid withdrawal to argue for research and public health programs aimed at preventing rather than just managing opioid addiction.
In this Viewpoint, US Surgeon General Jerome Adams summarizes his office’s 2018 Advisory on Naloxone and Opioid Overdose, which provides guidance on the use of naloxone to curb the number of opioid overdose deaths across the country.
This Viewpoint discusses how workplace lifestyle and health monitoring interventions can discourage and disengage employees when health measures fail to show positive change, and proposes that organizations develop coaching and psychological strategies to motivate employees who grow discouraged from an absence of clear change through their sense of failure.
This Viewpoint proposes a system for ranking the quality of risk adjustment methods as a way to more accurately account for health care quality and more transparently link payment incentives to performance and patient outcomes.
In this narrative medicine essay, a medical oncologist shares how little he understood of his patients’ pain and challenges while undergoing cancer treatment until his own diagnosis, which inspired working with administrators to help patients navigate the institutional labyrinth and provide transportation to and from treatment.
This JAMA Clinical Update reviews the evolution of procedures for treating coronary artery stenosis since 1977 and the role of percutaneous coronary intervention (PCI) in the management of acute coronary syndromes (NSTEMI and STEMI), stable and unstable angina, and stable multivessel disease.
A 28-year-old healthy woman had a 2-week history of dyspnea, cough, wheezing, and lithoptysis. She had a borderline elevated Histoplasma antigen level, and a chest computed tomography scan revealed a calcified subcarinal mass compromising the left main-stem bronchus lumen. What would you do next?
This Medical News story discusses the pros and cons of direct primary care, whose practitioners don’t accept insurance and instead charge a membership fee to cover services.
In this Medical News article, experts discuss the benefits and limitations of a blood test recently approved to evaluate patients with mild traumatic brain injury.
This JAMA Patient Page describes small bowel obstruction and its symptoms, diagnosis, and treatment.