This randomized clinical trial compares the effect on first-attempt success of intubation using a tracheal tube bougie introducer vs endotracheal tube with stylet in patients with difficult airway characteristics requiring emergency intubation.
This meta-analysis uses individual participant data from 5 randomized clinical trials to compare the effects of lower vs higher oxygen saturation target ranges on death or major morbidity among infants born before 28 weeks’ gestation.
This pooled cohort analysis assesses the association of quick Sequential (Sepsis-Related Organ Failure Assessment (qSOFA) score with excess hospital death among patients with suspected infection in low- to middle-income countries and compares the mortality association using qSOFA vs systemic inflammatory response syndrome (SIRS) criteria.
This case series describes 90-day mortality of patients who required tracheal, bronchial, or carinal reconstruction using stented aortic allografts supported by muscle flaps for treatment of inoperable airway disease including lung cancer, tracheal stenosis, or tracheomalacia.
This study uses US Department of Veterans Affairs (VA) data to characterize trends in the use of watchful waiting and active surveillance as strategies for managing low-risk prostate cancer in US veterans from 2005 through 2015.
In this Viewpoint, Peter Bach and colleagues distinguish 5 pricing reform proposals implied by the concept of value-based drug pricing and discuss the potential of each to ensure value in response to unsustainable drug price increases.
This Viewpoint proposes policy reforms to prioritize use and development of new cancer drugs that yield meaningful clinical benefit at sustainable prices.
This Viewpoint discusses the challenges of high prices for payers and high access barriers for patients for specialty drugs and how these can be addressed by value-based pricing and value-based patient access.
In this narrative medicine essay, a palliative care physician realizes that her inability to tolerate discomfort felt by her preschool-aged daughter is a survival technique in reaction to her experience of grief for her dying patients and comes to an understanding that the 2 roles complement each other.
This JAMA Guide to Statistics and Methods explains the rationale for permuted block randomization and for stratifying randomization in clinical trials.
This Clinical Evidence Synopsis summarizes a Cochrane review of randomized trials comparing the effects of hearing aids vs control interventions on health-related quality of life among adults with hearing loss.
This Clinical Guidelines Synopsis summarizes the 2017 American College of Cardiology (ACC)/American Heart Association (AHA)/Heart Rhythm Society (HRS) guideline for the evaluation and management of patients with syncope.
This Medical News story describes the growing trend of emergency departments initiating medication-assisted treatment with buprenorphine to patients with opioid use disorder.
In this medical news article, the author of a JAMA study reporting outcomes of tracheal or bronchial replacement surgery explains how he and his colleagues developed their techniques.
This Arts and Medicine essay reviews Botched, a reality television show featuring patients seeking revision plastic surgery, praising it for its realistic depiction of complications and bad outcomes against the trend of unrealistic representations of plastic surgery online and in social media.
This JAMA Patient Page describes common causes of eye injury and recommended treatment.