This noninferiority trial compares the effects on 28-day neurological outcomes of bag-mask vs mechanical ventilation after endotracheal intubation during cardiopulmonary resuscitation for out-of-hospital cardiac arrest (OHCA).
This noninferiority randomized trial compares the efficacy and safety of meropenem-vaborbactam vs piperacillin-tazobactam for treatment of adults with complicated urinary tract infection.
This cohort study examines the association between career participation in professional American football and mortality risk in retirement, and it compares causes of death among career vs replacement players.
This cohort study uses claims data from Taiwan’s National Health Insurance program to investigate associations between varicose veins and risk of deep venous thrombosis (DVT), pulmonary embolism (PE), and peripheral artery disease (PAD).
This study uses National Inpatient Sample survey data to characterize trends in red blood cell, plasma, and platelet transfusions in the United States between 1993 and 2014, a period of time during which trials were demonstrating the safety of restrictive red blood cell transfusion strategies.
This Viewpoint discusses the legality of waivers created by US states that allow work requirements to be enforced for nondisabled Medicaid beneficiaries.
This Viewpoint discusses international medical graduates practicing in the United States and Canada—benefits and drawbacks to remaining in North America or returning to their country of origin to practice.
This Viewpoint describes reforms to the ways the National Health Service (NHS) appraises cost-effectiveness and coverage of cancer drugs in England and Wales, the role of the National Institute for Health and Care Excellence (NICE) in the process, and changes in drug approval rates and access to new drugs as a result.
In this essay, the author struggles how to respond to a dying patient’s implicit request for the ultimate pain relief.
This Clinical Evidence Synopsis summarizes a 2017 Cochrane review on pain relief associated with use of gabapentin for patients with chronic neuropathic pain.
This JAMA Clinical Guidelines Synopsis summarizes the 2016 American Heart Association/American Stroke Association guideline on adult stroke rehabilitation and recovery.
This Medical Letter review compares a newly approved 2-dose hepatitis B virus vaccine that uses a synthetic oligonucleotide immunostimulatory adjuvant, and is licensed for use in adults, with other commercially available 3-dose vaccines.
This Medical News article discusses applications of augmented and virtual reality in medical education.
This JAMA Patient Page describes the evaluation and management of sport-related concussion.
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