This randomized clinical trial compares the effects of cervical HPV vs cytology (Pap smear) screening on the cumulative incidence of high-grade cervical intraepithelial neoplasia (CIN3+) detected at 48 months.
This pharmacoepidemiology study estimates the risk of hypoglycemia-related emergency department visits or hospital admissions associated with initiation of long-acting insulin analogs vs human neutral protamine Hagedorn (NPH) insulin in patients with type 2 diabetes.
This cross-sectional analysis uses data from the National Cardiovascular Data Registry to examine changes in the proportion of initial primary prevention implantable cardioverter-defibrillators placed that did not meet the CMS National Coverage Determination following the announcement of the US Department of Justice investigation at hospitals that did and did not reach settlements.
This cohort study uses electronic health record data to examine associations between maternal diabetes (preexisting type 1, type 2, and gestational) and autism spectrum disorder in children.
In this Viewpoint, Robert Wachter and Michael Howell from Google discuss the prospects that medicine is finally poised to realize improvements in quality, safety, and productivity from investments in health information technology and digitization, and from growing competencies in systems thinking and population health
This Viewpoint describes 4 major barriers to useful risk prediction that may not be easily overcome by new methods in machine learning and, in some instances, may be more difficult to overcome in the era of big data.
This Viewpoint summarizes a 2018 National Academies of Sciences, Engineering, and Medicine (NASEM) report that details challenges to support of biomedical scientists in the United States and proposes solutions, including public-private partnerships and a dedicated line of Congressional funding to support next-generation researchers and innovation.
In this Viewpoint, Insel and colleagues discuss the roles that private sector companies and foundations might play and the advantages of public-private partnerships in nurturing new and early-career physician-investigators given an always-challenging funding environment and ever-increasing hurdles young physicians must overcome to establish a research career.
In this narrative medicine essay, a pediatrician returns to the hospital after riding his bicycle home against a strong headwind to evaluate a neonate with a congenital heart defect and later reflects on whether medical payment for service motivates health care clinicians.
This narrative review article considers the increasing numbers of patients who contract the infection from cardiac surgical implants, increased intravenous drug use, and poor dental hygiene and discusses ways to treat it prophylactically, surgically, and medically.
This JAMA Guide to Statistics and Methods explains the correct usage of odds ratios in the clinical literature to report the strength of the association between binary outcomes.
This JAMA Clinical Guidelines Synopsis summarizes the American College of Gastroenterology’s 2016 guideline on management of patients with acute lower GI tract bleeding.
This Medical News article discusses a video game-based therapy for pediatric attention-deficit/hyperactivity disorder.
This Medical News story discusses the growing incidence of basal cell carcinoma and promising treatments for the disease.
This Arts and Medicine essay describes the use of wheelchair ballroom dance workshops to partner standing abled and seated disabled dancers as a means to equalize the 2 and challenge prevalent attitudes about disability.
This JAMA Patient Page describes the causes, symptoms, diagnosis, and treatment of infective endocarditis.
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