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December 2018 - July 1883

Decade

Year

Issue

October 2, 2018, Vol 320, No. 13, Pages 1297-1396

In This Issue of JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2018;320(13):1297-1299. doi:10.1001/jama.2017.12570
Viewpoint

Addressing the Tuberculosis Epidemic21st Century Research for an Ancient Disease

Abstract Full Text
JAMA. 2018;320(13):1315-1316. doi:10.1001/jama.2018.12852

In this Viewpoint, Anthony Fauci summarizes the National Institute of Allergy and Infectious Diseases’ (NIAID’s) 2018 Strategic Plan for Tuberculosis (TB), which comprises investments in development of point-of-care diagnostics, vaccines, shorter-duration therapeutics, and infrastructure for systems biology and “omics” approaches to the infection.

Crossing the Global Health Care Quality ChasmA Key Component of Universal Health Coverage

Abstract Full Text
JAMA. 2018;320(13):1317-1318. doi:10.1001/jama.2018.13696

In this Viewpoint, Don Berwick and colleagues summarize a 2018 National Academies of Sciences, Engineering, and Medicine (NASEM) report on global health care quality emphasizing that universal access will yield improvements in population health only when paired with quality reforms characterized by systems design, transparency, collaboration, anticipatory care, evidence-based decisions, and continuous feedback and learning.

Scientific Discovery and the Future of Medicine

Aging, Cell Senescence, and Chronic DiseaseEmerging Therapeutic Strategies

Abstract Full Text
JAMA. 2018;320(13):1319-1320. doi:10.1001/jama.2018.12440

This Viewpoint describes the processes by which aging of cells contributes to age-related decline, chronic disease, and multimorbidity, and describes current animal research and clinical trials investigating the effects of senolytic drugs and vaccines that target senescent cell antiapoptotic pathways and remove senescent cells.

Scientific Discovery and the Future of Medicine

Aging as a Biological Target for Prevention and Therapy

Abstract Full Text
JAMA. 2018;320(13):1321-1322. doi:10.1001/jama.2018.9562

This Viewpoint discusses targeting fundamental biological aging processes through nutritional, genetic, and pharmacologic interventions to delay or prevent the onset or progression of multiple chronic diseases and debilities typically observed in older humans to enhance and extend both health and longevity.

Scientific Discovery and the Future of Medicine

From Lifespan to Healthspan

Abstract Full Text
JAMA. 2018;320(13):1323-1324. doi:10.1001/jama.2018.12621

This viewpoint discusses increased life expectancy and the initiatives to address the risks and unintended consequences of living longer.

A Piece of My Mind

Nurturing Medicine

Abstract Full Text
JAMA. 2018;320(13):1325. doi:10.1001/jama.2018.13766

In this narrative medicine essay, a geriatric and palliative care physician shares his understanding that the patience, flexibility, humility, and presence required to grow a garden are entirely appropriate for end-of-life patient care.

Editorial

Physical Therapy or Arthroscopic Surgery for Treatment of Meniscal TearsIs Noninferiority Enough?

Abstract Full Text
JAMA. 2018;320(13):1326-1327. doi:10.1001/jama.2018.13181
Original Investigation

Effect of Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal TearsThe ESCAPE Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA. 2018;320(13):1328-1337. doi:10.1001/jama.2018.13308

This noninferiority trial compares the effects of arthroscopic partial meniscectomy vs physical therapy on patient-reported knee function in patients with meniscal tears.

Association of Clinical and Social Factors With Excess Hypertension Risk in Black Compared With White US Adults

Abstract Full Text
has active quiz
JAMA. 2018;320(13):1338-1348. doi:10.1001/jama.2018.13467

This cohort study of black and white adults investigates demographic, physical, and lifestyle factors that might account for differences in incidence of hypertension in black vs white US adults.

Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical HypothyroidismA Systematic Review and Meta-analysis

Abstract Full Text
JAMA. 2018;320(13):1349-1359. doi:10.1001/jama.2018.13770

This meta-analysis of randomized trials assesses the association of thyroid hormone therapy with quality of life (QOL) and thyroid-related symptoms in nonpregnant adults with subclinical hypothyroidism.

Review

Diagnosis and Management of Rheumatoid ArthritisA Review

Abstract Full Text
JAMA. 2018;320(13):1360-1372. doi:10.1001/jama.2018.13103

This narrative review summarizes current evidence regarding the pathophysiology, diagnosis, and treatment of rheumatoid arthritis.

JAMA Diagnostic Test Interpretation

Diagnostic Testing for Elevated Cortisol in the Setting of an Adrenal Mass

Abstract Full Text
JAMA. 2018;320(13):1373-1374. doi:10.1001/jama.2018.13351

An asymptomatic 66-year-old man had a 3.1-cm left adrenal mass detected on CT scan with normal vital signs, BMI of 37, normal physical examination, and an elevated cortisol level after an overnight 1-mg dexamethasone suppression test. What would you do next?

From The Medical Letter on Drugs and Therapeutics

Ciprofloxacin Otic Suspension (Otiprio) for Acute Otitis Externa

Abstract Full Text
JAMA. 2018;320(13):1375-1376. doi:10.1001/jama.2018.12787

This Medical Letter review summarizes clinical studies, adverse effects, dosage, and administration for a 6% otic suspension formulation of the fluoroquinolone antibiotic ciprofloxacin (Otiprio), approved by the US Food and Drug Administration in 2018 for single-dose treatment of acute otitis externa.

Research Letter

Electronic Cigarette Sales in the United States, 2013-2017

Abstract Full Text
JAMA. 2018;320(13):1379-1380. doi:10.1001/jama.2018.10488

This study uses e-cigarette retail sales data to estimate estimate e-cigarette sales and market share of e-cigarette sales by manufacturer in the United States during 2013-2017.

Presence of High-Intensity Sweeteners in Popular Cigarillos of Varying Flavor Profiles

Abstract Full Text
JAMA. 2018;320(13):1380-1383. doi:10.1001/jama.2018.11187

This Research Letter evaluates the amount of sugars found in cigarillos by brand.

Medical News & Perspectives

Cardiologist Trades Stem Cells for Cell-Based Meat

Abstract Full Text
has audio
JAMA. 2018;320(13):1303-1306. doi:10.1001/jama.2018.11895

Beef and poultry grown from animal cells rather than sourced from whole animals could be the future of meat production, a cardiologist-turned-biotech entrepreneur says in this Medical News article.

News From the Food and Drug Administration

Rare Infection Linked With SGLT-2 Inhibitor Use

Abstract Full Text
JAMA. 2018;320(13):1309. doi:10.1001/jama.2018.14128

Tretinoin in New Lotion Formula

Abstract Full Text
JAMA. 2018;320(13):1309. doi:10.1001/jama.2018.14129

New Drug Treats Rare, Debilitating Neurotrophic Keratitis

Abstract Full Text
JAMA. 2018;320(13):1309. doi:10.1001/jama.2018.14132
The JAMA Forum

Given Their Potential for Harm, It’s Time to Focus on the Safety of Supplements

Abstract Full Text
free access
JAMA. 2018;320(13):1306-1307. doi:10.1001/jama.2018.13147
Bench to Bedside

Gut Microbes May Account for the Anti-Seizure Effects of the Ketogenic Diet

Abstract Full Text
JAMA. 2018;320(13):1307. doi:10.1001/jama.2017.12865
Comment & Response

Glyburide vs Insulin for Gestational Diabetes

Abstract Full Text
JAMA. 2018;320(13):1383-1384. doi:10.1001/jama.2018.10086

Glyburide vs Insulin for Gestational Diabetes—Reply

Abstract Full Text
JAMA. 2018;320(13):1384. doi:10.1001/jama.2018.10090

Acupuncture for Women Undergoing In Vitro Fertilization

Abstract Full Text
JAMA. 2018;320(13):1384-1385. doi:10.1001/jama.2018.10542

Acupuncture for Women Undergoing In Vitro Fertilization

Abstract Full Text
JAMA. 2018;320(13):1385. doi:10.1001/jama.2018.10538

Acupuncture for Women Undergoing In Vitro Fertilization—Reply

Abstract Full Text
JAMA. 2018;320(13):1385-1386. doi:10.1001/jama.2018.10546

Factors Associated With Variation in Outcomes in Bariatric Surgery Centers of Excellence

Abstract Full Text
JAMA. 2018;320(13):1386-1387. doi:10.1001/jama.2018.11194

Factors Associated With Variation in Outcomes in Bariatric Surgery Centers of Excellence—Reply

Abstract Full Text
JAMA. 2018;320(13):1387. doi:10.1001/jama.2018.11206
Correction

Incorrect Information in Patient Page

Abstract Full Text
free access
JAMA. 2018;320(13):1387. doi:10.1001/jama.2018.13459

Incorrect Units

Abstract Full Text
free access
JAMA. 2018;320(13):1387. doi:10.1001/jama.2018.13822

Incorrect Data or Information

Abstract Full Text
free access
JAMA. 2018;320(13):1387. doi:10.1001/jama.2018.12240

Corrected Data for Survey Results in Viewpoint

Abstract Full Text
free access
JAMA. 2018;320(13):1387. doi:10.1001/jama.2018.14161
Poetry and Medicine

Vitreous

Abstract Full Text
JAMA. 2018;320(13):1388. doi:10.1001/jama.2018.8427
JAMA Revisited

The Book Forum

Abstract Full Text
JAMA. 2018;320(13):1389. doi:10.1001/jama.2017.12600
JAMA Patient Page

Tinea Versicolor

Abstract Full Text
free access
JAMA. 2018;320(13):1396. doi:10.1001/jama.2018.12429

This JAMA Patient Page describes tinea versicolor and its symptoms, diagnosis, and treatment.

JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2018;320(13):1301-1302. doi:10.1001/jama.2017.12571
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